Azacytidine induces necrosis of multiple myeloma cells through oxidative stress

Tian, Enbing; Tang, Haiping; Xu, Renhua; Liu, Chongdong; Deng, Haiteng; Wang, Qingtao

doi:10.1186/1477-5956-11-24

Proteome Science

Table 2 Down-regulated proteins after treatment with 100 μM azacytidine

From: Azacytidine induces necrosis of multiple myeloma cells through oxidative stress

Down regulated proteins		Fold changes
IPI00003865	Isoform 1 of Heat shock cognate 71 kDa protein	0.5
IPI00414676	Heat shock protein HSP 90-beta	0.7
IPI00784295	Isoform 1 of Heat shock protein HSP 90-alpha	0.6
IPI00220740	Isoform 2 of Nucleophosmin	0.2
IPI00018465	T-complex protein 1 subunit eta	0.7
IPI00179330	Ubiquitin-40S ribosomal protein S27a	0.4
IPI00985384	ATP-dependent RNA helicase DDX3X isoform 3	0.2
IPI00027547	Dermcidin	0.2
IPI00376143	DNA replication licensing factor MCM7 isoform 2	0.3
IPI00786995	DNA-dependent protein kinase catalytic subunit-like	0.2
IPI00002966	Heat shock 70 kDa protein 4	0.4
IPI00027107	elongation factor Tu, mitochondrial precursor	0.4
IPI00026781	Fatty acid synthase	0.4
IPI00015018	Inorganic pyrophosphatase	0.5
IPI00008557	Insulin-like growth factor 2 mRNA-binding protein 1	0.4
IPI00000816	Isoform 1 of 14-3-3 protein epsilon	0.5
IPI00658000	Isoform 1 of Insulin-like growth factor 2 mRNA-binding protein 3	0.1
IPI00455383	Isoform 2 of Clathrin heavy chain 1	0.5
IPI00883762	Isoform 2 of Cytosolic acyl coenzyme A thioester hydrolase	0.1
IPI00025273	Isoform Long of Trifunctional purine biosynthetic protein adenosine-3	0.4
IPI00216230	Lamina-associated polypeptide 2, isoform alpha	0.5
IPI00170935	Leucine-rich repeat-containing protein 47	0.1
IPI00017297	Matrin-3	0.1
IPI00016610	Poly(rC)-binding protein 1	0.5
IPI00017617	Probable ATP-dependent RNA helicase DDX5	0.5
IPI00550451	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit	0.2
IPI00947285	suprabasin isoform 1 precursor	0.3
IPI00216049	Isoform 1 of Heterogeneous nuclear ribonucleoprotein K	0.1
IPI01011912	Phosphoglycerate kinase	0.5
IPI00549725	Phosphoglyceratemutase 1	0.2
IPI00645452	Tubulin, beta	0.3
IPI00179964	Isoform 1 of Polypyrimidine tract-binding protein 1	0.3
IPI00217465	Histone H1.2	0.4
IPI00783271	Leucine-rich PPR motif-containing protein, mitochondrial	0.5
IPI00219365	Moesin	0.6
IPI00396485	Elongation factor 1-alpha 1	0.4
IPI00419258	High mobility group protein B1	0.3
IPI00031812	Nuclease-sensitive element-binding protein 1	0.3
IPI00465439	Fructose-bisphosphatealdolase A	0.5
IPI00217223	Multifunctional protein ADE2	0.4
IPI00550363	Transgelin-2	0.5
IPI00917777	116 kDa U5 small nuclear ribonucleoprotein component isoform b	0.5
IPI00100160	Isoform 1 of Cullin-associated NEDD8-dissociated protein 1	0.5
IPI00793443	Isoform 1 of Importin-5	0.4
IPI00449049	Poly [ADP-ribose] polymerase 1	0.6
IPI00007797	Fatty acid-binding protein, epidermal	0.4
IPI00398625	Hornerin	0.4
IPI00843975	Ezrin	0.6
IPI00465248	Isoform alpha-enolase of Alpha-enolase	0.5
IPI00645078	Ubiquitin-like modifier-activating enzyme 1	0.4

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ISSN: 1477-5956

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