Table 1 Protein classes significantly altered during aging of A.BY/SnJ mice*
From: Proteomic analyses of age related changes in A.BY/SnJ mouse hearts
Functional class | Acc. No | Protein name | 2D-DIGE | LC-MS/MS |
|---|---|---|---|---|
Protein transport | Q8VBT1 | Beta-taxilin | 3.67 | n.d. |
Q8VCM7 | Fibrinogen gamma chain | 3.63 | n.d. | |
Q91YP2 | Neurolysin, mitochondrial | 1.85 | n.d. | |
Q1XH17 | Tripartite motif-containing protein 72 | 1.68 | 0.91 | |
O89053 | Coronin-1A | 1.60 | n.d. | |
P61979 | Heterogeneous nuclear ribonucleoprotein K | 0.06 | 0.39 | |
Q01853 | Transitional endoplasmic reticulum ATPase | 1.41 | ||
Q541Z9 | Rab GDP dissociation inhibitor beta | 3.86 | ||
Q8BGK2 | [Protein ADP-ribosylarginine] hydrolase-like protein 1 | 3.54 | ||
Lipid metabolism | Q80XN0 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial | 12.20 | |
Q924X2 | Carnitine O-palmitoyltransferase 1, muscle isoform | 1.87 | ||
Q99NB1 | Acetyl-coenzyme A synthetase 2-like, mitochondrial | 1.64 | ||
P52825 | Carnitine O-palmitoyltransferase 2, mitochondrial | 1.58 | ||
P47934 | Carnitine O-acetyltransferase | 1.48 | ||
Respiratory ETC./Energy metabolism | Q9CQJ8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 | 2.35 | |
Q9DC69 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | 2.05 | ||
Q9DCS9 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 | 1.56 | ||
Q61941 | NAD(P) transhydrogenase, mitochondrial | 1.43 | ||
Q03265 | ATP synthase subunit alpha, mitochondrial | 0.83 | ||
Q9D3D9 | ATP synthase subunit delta, mitochondrial | 0.82 | ||
P62897 | Cytochrome c, somatic | 0.64 | ||
P56392 | Cytochrome c oxidase polypeptide 7A1, mitochondrial | 0.41 | ||
Q9CQC7 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 | 0.36 | ||
Q8K2B3 | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | 2.93 | 1.11 | |
Q60597 | 2-oxoglutarate dehydrogenase E1 component, mitochondrial | 1.82/1.51 | 1.39 |