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Table 5 Clinical features of patients in different AML groups before chemotherapy

From: Potential biomarkers for adult acute myeloid leukemia minimal residual disease assessment searched by serum peptidome profiling

Clinical features

 

AML

  

Newly diagnosed

CR

Refractory & relapsed

Sex

male

38

19

13

female

34

18

17

Age(year)

 

46(18–79)

48(18–69)

47(19–77)

WBC(×109/L)

 

23.5(0.25-143)

11.83(2.96-101.69)

23.58(0.94-123.6)

Hb(g/L)

 

73(28–128)

111.5(69–135)

69(55–152)

PLT(×109/L)

 

26(12–287)

74(48–174)

31(9–172)

Subtype

 

M0

0

M0

0

M0

0

M1

6

M1

2

M1

3

M2

8

M2

5

M2

2

M3

6

M3

5

M3

0

M4

24

M4

11

M4

13

M5

28

M5

14

M5

12

M6

0

M6

0

M6

0

M7

0

M7

0

M7

0

Chromosome Abnormality

 

t(15;17)

6

t(15;17)

5

t(8;21)

1

t(8;21)

4

t(8;21);

2

t(3;12)

2

t(3;12)

2

11q23

2

11q23

4

11q23

6

  

+8

3

+8

4

  

−7

2

−7

2

    

Molecular Genetics Abnormality

 

PML-RARa

6

PML-RARa

5

AML-ETO

1

AML-ETO

4

AML-ETO

2

MLL

3

MLL

6

  

FLT3-ITD

5

FLT3-ITD

6

  

C-kit Mut

2

C-kit

3

  

NPM1 Mut

3

NPM1 Mut

3

    

Sternal tenderness

 

57/72

 

25/37

 

26/30

 

Lymphadenectasis

 

39/72

 

14/37

 

21/30

 

Splenohepatomegalia

 

36/72

 

16/37

 

14/30

 

Curative effect

 

32/72

 

37/37

 

17/30

 
  1. This table showed clinical features of AML patients in different groups at the time of diagnosis. MLL refers to MLL rearrangement. Mut is the abbreviation of mutation. Curative effect refers to achieved complete remission after 2 courses of standard chemotherapy.