Figure 9
From: Exploring the “dark matter” of a mammalian proteome by protein structure and function modeling
Examples of ligands binding to sproteins. Ten top-ranked KEGG compounds selected by virtual screening against sproteins (KEGG-ID and the average Z-score from virtual screening against 1,100 binding sites in sproteins are given in parentheses): (A) O-acetylneuraminic acid (C03525, 1.042), (B) O-D-alanyl-poly(ribitol phosphate) (C04260, 1.014), (C) aconitine (C06091, 0.952), (D) cyclopentolate (C06932, 0.950), (E) candoxatrilat (C11721, 0.944), (F) D-glucosaminate (C03752, 0.902), (G) enicoflavine (C09946, 0.854), (H) 5-O-feruloylquinic acid (C02572, 0.812), (I) serratine (C09901, 0.805), and (J) 3-phosphoglycerol-glutathione (C03928, 0.761).