Proteome Science

Table 4 CESSM results of semantic similarities in MF ontology with IEA annotations.

From: M-Finder: Uncovering functionally associated proteins from interactome data integrated with GO annotations

Similarity	Resnik	Lin	Jiang	simUI	simGIC	G-SESAME	simICNP	simICND
Sequence	0.668	0.606	0.546	0.592	0.717	0.398	0.674	0.710
Pfam	0.572	0.564	0.491	0.618	0.638	0.498	0.660	0.673
ECC	0.603	0.642	0.561	0.637	0.622	0.714	0.752	0.744
Resolution	0.958	0.571	0.241	0.967	0.956	0.334	0.931	0.963

The semantic similarities in MF ontology from eight different methods were compared in terms of correlations with the similarities of other functional features. To measure semantic similarity, IEA annotations were included.

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ISSN: 1477-5956

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