Proteome Science

Table 5 CESSM results of semantic similarities in MF ontology without IEA annotations.

From: M-Finder: Uncovering functionally associated proteins from interactome data integrated with GO annotations

Similarity	Resnik	Lin	Jiang	simUI	simGIC	G-SESAME	simICNP	simICND
Sequence	0.651	0.598	0.522	0.591	0.666	0.439	0.679	0.708
Pfam	0.522	0.515	0.450	0.550	0.582	0.416	0.605	0.587
ECC	0.484	0.516	0.519	0.578	0.587	0.564	0.598	0.567
Resolution	0.934	0.938	0.364	0.930	0.936	0.595	0.830	0.982

The semantic similarities in MF ontology from eight different methods were compared in terms of correlations with the similarities of other functional features. To measure semantic similarity, IEA annotations were excluded.

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ISSN: 1477-5956

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