Figure 4
From: Ranking and compacting binding segments of protein families using aligned pattern clusters
One three-dimensional structure from the cytochrome c protein family, PDB ID 1F1F, is displayed. The top-two statistically significant APCs from the cytochrome c protein are the proximal binding segment (in pink) and the distal binding segment (in blue) that bind the heme from above and below the horizontal plane, respectively. More specifically, one specific amino acid from each of the two segments binds the iron molecule from the centre of the heme: the "H" (Histidine) residue at position 18 of the proximal segment and the "M" (Methionine) residue at position 62 of the distal segment.