Table 2 Functional classification of differentially expressed platelet proteins between healthy control and patients with major depression by using BiNGO 2.44 software
From: 2D-DIGE proteome analysis on the platelet proteins of patients with major depression
Component | Protein symbols* |
|---|---|
Cytoplasm | FIBB, FIBG, TCPB, GPX1, FIBG, RARB, GPX1, PDIA3 |
Membrane-bound vesicle | FIBG, PDIA3, FIBB |
Stored secretory granule | FIBG, FIBB |
Nucleus | SH319, RARB |
Chaperone-containing T-complex | TCPB |
Molecular function | |
Protein binding | FIBB, FIBG, TCPB, GPX1, FIBG, RARB, GPX1, PDIA3 |
Cell surface binding | FIBG, FIBB |
Retinoic acid receptor activity | RARB |
Proline-rich region binding | SH319 |
Intramolecular oxidoreductase activity | PDIA3 |
Glutathione peroxidase activity | GPX1 |
Biological process | |
Wound healing, response to metal ion | FIBG, FIBB, GPX1 |
Positive regulation of cell death | PDIA3, RARB, GPX1 |
Protein polymerization | FIBG, FIBB |
Muscle cell differentiation | RARB, GPX1 |
Cell redox homeostasis | PDIA3, GPX1 |