Table 1 Differentially expressed proteins at 3 days post-lesioning
Protein name | Average iTRAQ ratio (3 days post-lesion/unlesioned) | p value |
|---|---|---|
Down-regulated | ||
Diacylglycerol kinase beta [9506535] | 0.57 +/− 0.2 [4] | 0.0192 |
Synaptophysin [6981622] | 0.59 +/− 0.18 [5] | 0.0035 |
Synaptic ras GTPase-activating protein p135 SynGAP [2935448] | 0.62 +/− 0.1 [7] | 2.92E-05 |
Ras-related protein Rab-3C [19424194] | 0.67 +/− 0.13 [5] | 0.0029 |
Protein NipSnap homolog 2 [62945328] | 0.67 +/− 0.06 [3] | 0.0066 |
Prohibitin [6679299] | 0.67 +/− 0.26 [6] | 0.0069 |
Succinyl-CoA synthetase alpha subunit [204356] | 0.69 +/− 0.26 [5] | 0.0486 |
RII-B-binding protein [557585] | 0.69 +/− 0.12 [4] | 0.0074 |
Type II cAMP-dependent protein kinase regulatory subunit [206671] | 0.70 +/− 0.14 [16] | 3.45E-08 |
A-kinase anchor protein 5 [19424156] | 0.71 +/− 0.22 [5] | 0.0276 |
RNA binding protein p37 AUF1 [9588102] | 0.71 +/− 0.3 [6] | 0.0325 |
Erythrocyte adducin subunit beta [10720378] | 0.72 +/− 0.12 [6] | 0.0010 |
Septin-5 [90577179] | 0.72 +/− 0.09 [7] | 0.0001 |
Reticulon-3 isoform A [57977297] | 0.72 +/− 0.18 [5] | 0.0151 |
Homer protein homolog 1 [13928988] | 0.73 +/− 0.26 [6] | 0.0484 |
Ras-related protein Rab-3C [13470090] | 0.74 +/− 0.15 [5] | 0.0093 |
V-type proton ATPase 116 kDa subunit a isoform 1 [139352] | 0.75 +/− 0.22 [8] | 0.0107 |
Up-regulated | ||
Tenascin-R precursor [6981668] | 1.25 +/− 0.64 [8] | 0.0545 |
Cytoplasmic dynein 1 light intermediate chain 1 [21955134] | 1.25 +/− 0.12 [3] | 0.0409 |
Rap1b [595280] | 1.25 +/− 0.08 [4] | 0.0048 |
G protein beta 1 subunit [984553] | 1.27 +/− 0.36 [7] | 0.0373 |
6-phosphofructokinase, muscle type [13929002] | 1.27 +/− 0.47 [8] | 0.0482 |
Transketolase [12018252] | 1.27 +/− 0.32 [6] | 0.0429 |
Guanine deaminase [148747414] | 1.30 +/− 0.8 [14] | 0.0453 |
Band 4.1-like protein 3 [16758808] | 1.31 +/− 0.51 [10] | 0.0145 |
Similar to 14-3-3 protein sigma [51260816] | 1.34 +/− 0.3 [5] | 0.0378 |
Eukaryotic initiation factor 4A-I isoform 1 [4503529] | 1.34 +/− 0.25 [4] | 0.0425 |
Reticulon-4 [13929188] | 1.36 +/− 0.26 [6] | 0.0080 |
Dihydropyrimidinase-related protein 4 [3122037] | 1.38 +/− 0.35 [7] | 0.0117 |
cGMP-dependent 3',5'-cyclic phosphodiesterase isoform 2 [13592021] | 1.45 +/− 0.64 [6] | 0.0544 |
Glutathione S-transferase P [25453420] | 1.48 +/− 0.18 [4] | 0.0067 |
Cytosol aminopeptidase [58865398] | 1.53 +/− 0.4 [5] | 0.0166 |
Glycyl-tRNA synthetase; [81889021] | 1.54 +/− 0.24 [3] | 0.0353 |
Chondroitin sulfate proteoglycan core protein 2 [21431624] | 1.61 +/− 0.66 [4] | 0.0585 |
Platelet-activating factor acetylhydrolase IB subunit alpha [7305363] | 1.77 +/− 0.4 [3] | 0.0409 |
NAD-dependent deacetylase sirtuin-2 [56605812] | 1.78 +/− 0.51 [9] | 0.0005 |
Carbonic anhydrase 2 [9506445] | 1.79 +/− 0.54 [6] | 0.0049 |
Myelin-oligodendrocyte glycoprotein precursor [158262022] | 1.85 +/− 0.2 [5] | 0.0005 |
Myelin proteolipid protein [13591880] | 1.85 +/− 0.62 [17] | 5.15E-06 |
Myelin basic protein [4454317] | 1.86 +/− 0.59 [14] | 1.84E-05 |
PMES-2C [55700833] | 1.87 +/− 0.62 [4] | 0.0307 |
Alpha-internexin [9506811] | 1.87 +/− 0.54 [18] | 1.5E-07 |
NF-M protein [205688] | 1.90 +/− 0.53 [19] | 8.36E-09 |
Myelin basic protein isoform 4 [70166270] | 1.92 +/− 0.61 [15] | 4.4E-06 |
Neurofilament light polypeptide [13929098] | 1.92 +/− 0.64 [11] | 4.56E-05 |
2',3'-cyclic-nucleotide 3'-phosphodiesterase [57977323] | 1.92 +/− 0.59 [29] | 5.17E-11 |
High molecular-weight neurofilament [2642598] | 1.98 +/− 0.75 [8] | 0.0006 |
Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic [57527919] | 1.99 +/− 0.32 [3] | 0.0216 |
Glial fibrillary acidic protein [158186732] | 3.44 +/− 2.58 [8] | 0.0118 |