Table 1 Proteins identified by MALDI-TOF analysis
Accession number | Protein | Function | pI/MW (kDa) | Peptides match/% | Variation |
|---|---|---|---|---|---|
P35213 | 14-3-3 isoform zeta, PKC inhibitor | Signal transduction | 5.5/28 | 9/40 | ↑ I/R, ↑ Atorva |
P35213 | 14-3-3 protein beta/alpha | Signal transduction | 4.8/28 | 7/31 | ↑ Atorva, ↓ Feno |
P45953 | Acyl-CoA dehydrogenase, very long chain specific | Lipid Metabolism, Mito | 9.0/70.8 | 4/16 | ↑ I/R |
P84079 | ADP rybosilation factor 1 | Trafficking | 6.3/20.7 | 4/16 | ↑ I/R |
Q9Z0U5 | Aldehyde oxidase precursor | Redox regulation | 6.5/146.9 | 5/25 | ↑↑ I/R, ↑I/R Atorva, ↑, I/R Feno |
P37840 | Alpha-synuclein | Presynaptic/axon | 4.7/14.5 | 4/11 | ↓ I/R, ↓ Atorva |
P23565 | Alpha-internexin | Intermediate filament | 5.2/56.2 | 5/26 | ↓ I/R |
Q63754 | Beta-synuclein | Neuronal plasticity | 4.5/14.3 | 5/17 | ↑ I/R |
Q05175 | Brain acid soluble membrane protein (NAP 22) | Growth cone/axon | 4.5/21.8 | 4/15 | ↑ I/R |
O88767 | DJ-1 | Pleiotropic | 6.3/20 | 5/31 | ↓ I/R |
P11598 | Glucose related protein 58 kDa/PDIA3/Erp60 | Thioredoxin/protein folding | 5.9/57.6 | 4/17 | ↑ I/R, ↓ Atorva |
O35077 | Glycerol-phosphate-deshydrogenase | Metabolism | 6.3/38 | 2/11 | ↑ I/R |
O35796 | GCQ1QBP Glycoprotein | Complement/Mito | 4.8/30.7 | 4/21 | ↓ I/R |
P63039 | HSP 60 | Protein folding | 8.2/58.08 | 5/14 | ↑ I/R |
Q07439 | HSP 70.1/2 | Protein folding | 5.5/70.3 | 3/14 | ↓ I/R |
P34058 | HSP 90 beta | Protein folding | 5.1/83.4 | 7/38 | ↑ Feno |
Q62689 | Janus Kinase 2 | Tyrosine kinase/inflammation | 7.1/130.5 | 7/30 | ↓ I/R, ↑ Atorva |
P42123 | Lactate dehydrogenase B chain | Metabolism | 5.7/36.6 | 6/25 | ↓ I/R |
P40925 | Malate dehydrogenase | Metabolism | 6.2/36.7 | 3/15 | ↑ I/R |
Q62599 | Metastasis associated protein 1 | Unknown brain function | 9.2/79.4 | 4/26 | ↓ I/R |
P52590 | Nucleoporine 107 | Nuclear pore | 5.3/107.2 | 4/26 | ↓ I/R |
P35704 | Peroxiredoxine 2 | Redox regulation | 5.3/21.8 | 6/42 | ↑ Feno |
P31044 | Phosphatidylethanolamine-binding protein | Serine protease inhibitor | 5.5/20.8 | 6/17 | ↓ I/R |
P35291 | Rab16 | Trafficking | 5.0/22 | 4/25 | ↑ Atorva, ↑ Feno |
P49803 | Regulator of G protein signaling 7 | Signal transduction | 8.3/55.7 | 4/50 | ↑ I/R |
P11507 | Serca 2 | Calcium Homeostasis | 5.2/114.7 | 12/14 | ↓ I/R |
P21707 | Synaptotagmin I | Synapse | 8.8/47.8 | 4/22 | ↑ I/R |
P47942 | TUC-4 / TOAD 64 (DYPL/CRMP) | Axonal guidance/development | 6.0/62.2 | 15/71 | ↑ I/R |