Dynamic changes of urinary proteins in a focal segmental glomerulosclerosis rat model

Table 1 Comparison of human orthologs of changed proteins with urine, plasma and kidney origin proteome

Corresponding human protein ID	Protein name	Plasma proteome	Urine proteome	Kidney origin proteome	Stable protein	Candidate biomarkers of diseases
P01009	Alpha-1-antiproteinase	Yes	Yes	Yes	Yes	FSGS [22]
P43652	Afamin	Yes	Yes	Yes	Yes	Diabetic nephropathy [23]
P02768	Serum albumin	Yes	Yes	Yes	Yes	Adriamycin nephropathy mice model [24]
P00450	Ceruloplasmin	Yes	Yes	Yes	Yes	Diabetic nephropathy [25]
P01042	Kininogen-1	Yes	Yes	Yes	Yes	Adriamycin nephropathy rat model [26]
P02787	Serotransferrin	Yes	Yes	Yes	Yes	Adriamycin nephropathy mice model [24]
P23141	Carboxylesterase 1	Yes	Yes	No	No	None
P01861	Ig gamma-4 chain C region	Yes	Yes	No	No	Kidney calculi [27]
P00747	Plasminogen	Yes	Yes	No	Yes	Acute appendicitis [28]
P02765	Alpha-2-HS-glycoprotein	Yes	Yes	Yes	Yes	Diabetic nephropathy [23]
P02760	Protein AMBP	Yes	Yes	Yes	Yes	FSGS [22]
Q96D42	T-cell immunoglobulin and mucin domain-containing protein 1	No	No	No	No	Renal cell carcinoma [29], acute renal failure [30]
P19022	Cadherin-2	Yes	Yes	No	Yes	Ureteropelvic junction obstruction [31]
Q6PID9	Aggrecan core protein	No	Yes	No	No	None
P00746	Complement factor D	Yes	Yes	No	No	Dents disease [32]
P02749	Beta-2-glycoprotein 1	Yes	Yes	No	Yes	Dents disease [32]
Q13740	CD166 antigen	Yes	No	No	No	None
P06870	Kallikrein-1	No	Yes	No	Yes	None
P61769	Beta-2-microglobulin	Yes	Yes	Yes	Yes	Renal Interstitial Inflammation [33]
Q9UGM5	Fetuin-B	Yes	Yes	Yes	No	None

ISSN: 1477-5956