Table 1 List of identified proteins in the 2D-DIGE analysis of NSTEACS patients vs healthy controls
From: The plasma proteomic signature as a strategic tool for early diagnosis of acute coronary syndrome
Spot | Protein | Accession number | Mascot score | Ratio P/C | Theoretical MW (Da) | Theoretical PI | Exp MW (Da) | Exp PI | Biological function |
|---|---|---|---|---|---|---|---|---|---|
1 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4_HUMAN | 143 | 1.68 | 103357.43 | 6.51 | 65501 | 4.98 | Inflammation |
2 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4_HUMAN | 91 | 1.76 | 103357.43 | 6.51 | 65295 | 5.01 | Inflammation |
3 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4_HUMAN | 81 | 1.51 | 103357.43 | 6.51 | 65226 | 5.03 | Inflammation |
4 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4_HUMAN | 169 | 1.71 | 103357.43 | 6.51 | 65158 | 5.12 | Inflammation |
5 | Ceruloplasmin | CERU_HUMAN | 100 | 1.52 | 122205.19 | 5.44 | 64849 | 5.18 | Transport |
6 | Ceruloplasmin | CERU_HUMAN | 163 | 1.56 | 122205.19 | 5.44 | 67216 | 5.34 | Transport |
7 | Complement factor H | CFAH_HUMAN | 102 | -1.69 | 137052.59 | 6.12 | 66942 | 5.45 | Immunity |
8 | Complement factor H | CFAH_HUMAN | 171 | -1.53 | 137052.59 | 6.12 | 67045 | 5.47 | Immunity |
9 | Complement factor H | CFAH_HUMAN | 242 | -1.63 | 137052.59 | 6.12 | 67113 | 5.49 | Immunity |
10 | Complement C1r subcomponent | C1R_HUMAN | 225 | 1.59 | 78213.16 | 5.76 | 60663 | 5.38 | Inflammation |
11 | Alpha-1-antichymotrypsin | AACT_HUMAN | 104 | 3.16 | 47650.87 | 5.33 | 55105 | 4.94 | Inflammation |
11 | Kininogen-1 | KNG1_HUMAN | 450 | 3.16 | 69896.70 | 6.23 | 55105 | 4.94 | Inflammation |
12 | Antithrombin-III | ANT3_PONAB | 150 | 2.86 | 49039.14 | 5.95 | 54556 | 5.27 | Coagulation |
13 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4_HUMAN | 165 | -1.81 | 103357.43 | 6.51 | 51674 | 5.50 | Inflammation |
14 | Beta-Ala-His dispeptidase | CNDP1_HUMAN | 431 | 1.53 | 56692.06 | 5.14 | 56477 | 4.68 | Proteolysis |
14 | Vitronectin | VTNC_HUMAN | 221 | 1.53 | 54305.59 | 5.55 | 56477 | 4.68 | Inflammation |
14 | Alpha-1-antichymotrypsin | AACT_HUMAN | 131 | 1.53 | 47650.87 | 5.33 | 56477 | 4.68 | Inflammation |
15 | Gamma fibrinogen | FIBG_HUMAN | 182 | -2.21 | 48483.03 | 5.24 | 49821 | 5.07 | Coagulation |
16 | Ceruloplasmin | CERU_HUMAN | 173 | -2.63 | 122205.19 | 5.44 | 45841 | 5.09 | Transport |
16 | Apolipoprotein A-IV | APOA4_HUMAN | 121 | -2.63 | 45399.06 | 5.28 | 45841 | 5.09 | Transport |
17 | Vitamin D binding protein | VTDB_HUMAN | 163 | -1.88 | 52963.65 | 5.40 | 47522 | 5.17 | Transport |
18 | Hemopexin | HEMO_HUMAN | 140 | -2.37 | 51676.37 | 6.55 | 44297 | 5.42 | Transport |
19 | Complement factor H related protein-1 | FHR1_HUMAN | 188 | -3.19 | 35738.20 | 7.10 | 44400 | 5.56 | Inflammation |
20 | Catalytic chain carboxypeptidase N | CBPN_HUMAN | 228 | -1.58 | 50034.39 | 6.88 | 44743 | 6.19 | Peptidase |
21 | Leucin rich alpha-2-glicoprotein | A2GL_HUMAN | 143 | -2.01 | 34346.41 | 5.66 | 45326 | 4.47 | Unknown |
22 | Kininogen-1 | KNG1_HUMAN | 79 | -1.71 | 69896.70 | 6.23 | 40969 | 4.53 | Inflammation |
23 | Heparin cofactor 2 | HEP2_HUMAN | 103 | -1.51 | 54960.02 | 6.26 | 36234 | 4.64 | Coagulation |
24 | Complement C1r subcomponent | C1R_HUMAN | 105 | -1.75 | 78213.16 | 5.76 | 35445 | 5.13 | Inflammation |
25 | Apolipoprotein E | APOE_HUMAN | 87 | -1.80 | 34236.68 | 5.52 | 35960 | 5.38 | Transport |
26 | Ficolin-3 | FCN3_HUMAN | 127 | -1.83 | 32902.98 | 6.22 | 36612 | 5.68 | Inflammation |
27 | Complement factor H | CFAH_HUMAN | 199 | -1.93 | 137052.59 | 6.12 | 36509 | 5.83 | Inflammation |
28 | Complement factor H | CFAH_HUMAN | 169 | -1.78 | 137052.59 | 6.12 | 36268 | 5.99 | Inflammation |
29 | Antithrombin-III | ANT3_HUMAN | 138 | -2.08 | 49039.14 | 5.95 | 21652 | 5.18 | Coagulation |
30 | Apolipoprotein A-I | APOA1_HUMAN | 101 | -2.68 | 28078.62 | 5.27 | 23333 | 5.48 | Transport |
31 | Retinol binding protein 4 | RET4_HUMAN | 80 | -1.52 | 21071.60 | 5.27 | 17844 | 5.61 | Transport |
32 | Kininogen-1 | KNG1_HUMAN | 142 | -2.37 | 69896.70 | 6.23 | 13452 | 4.68- | Inflammation |
33 | Kininogen-1 | KNG1_HUMAN | 143 | -2.37 | 69896.70 | 6.23 | 11016 | 4.82 | Inflammation |
34 | Apolipoprotein A-IV | APOA4_HUMAN | 204 | -2.97 | 45399.06 | 5.28 | 7173 | 4.74 | Transport |
35 | Fibronectin | FINC_HUMAN | 185 | 1.66 | 259562.86 | 5.40 | 55654 | 5.98 | Inflammation |
35 | Alpha-2-macroglobulin | A2MG_HUMAN | 174 | 1.66 | 160809.88 | 5.98 | 55654 | 5.98 | Coagulation |