Table 3 Differentially regulated proteins in the SM7 tumour

777

40 kDa peptidyl-prolyl cis-trans isomerase PPID_MOUSE

TLENVEVNGEKPAK (160–173)

2

66

39,459

5.23

Up

ILLISEDLK (218–226)

2

EYDQALADLK (321–330)

3

1124

Acyl-protein thioesterase 1 LYPA1-MOUSE

ASFQGPINSANR (150–162)

2

54

25,565

5.88

Up

1400

NudC domain- containing protein 2 NUDC2_MOUSE

AQDIQCGLQSR (40–50)

2

57

16,128

4.76

Up

1470

40S ribosomal protein S12 RS12_MOUSE/Galectin-7LEG7_MOUSE

AEEGIAAGGVMDVNTALQEVLK (1–22) (Acetyl N-term)

2

125

14,314

7.83

Up

LGEWVGLCK (84–92)/

2

LTDSEVVFNTK (54–64)

2

81

467

Coronin-1A COR1A_MOUSE

VSQTTWDSGFCAVNPK (30–45)

2

267

54,369

6.95

Down

DGALICTSCR (187–196)

2

ILTTGFSR (234–241)

2

QVALWDTK (246–253)

2

DAGPLLISLK (384–393)

2

ATPEPSGTPSSDTVSR (417–432)

2

453

Coronin-1A COR1A_MOUSE

ADQCYEDVR (21–29)

2

123

54,503

6.59

Down

VSQTTWDSGFCAVNPK (30–45)

2

DAGPLLISLK (384–393)

2

460

Coronin-1A COR1A_MOUSE

VSQTTWDSGFCAVNPK (30–45)

2

185

54,503

6.74

Down

ILTTGFSR (234–241)

2

DAGPLLISLK (384–393)

2

ATPEPSGTPSSDTVSR (417–432)

2

700

Adenosine deaminase ADA_MOUSE

AQTPAFNKPK (1–10) (Acetyl N-term)

2

130/188

41,426

5.83

Down

GIALPADTVEELR (34–46)

2

IAYEFVEMK (81–89)

2

EGVVYVEVR (93–101)

2

ANYSLNTDDPLIFK (288–301)

2

727

Heterogeneous nuclear ribonucleoprotein A/B ROAA_MOUSE

IFVGGLNPEATEEK (161–174)

2

15**

40,430

6.69

Down

823

4-hydroxyphenyl puruvate dioxygenase HPPD_MOUSE

TEDIITAIR (270–278)

2

28*

36,980

6.66

Down

835

Eukaryotic translation initiation factor 3 subunit 2 IF32_MOUSE

SYSSGGEDGYVR (299–310)

2

56/51

36,622

5.89

Down

1216

Ras-related protein Rab-11B RB11B_MOUSE/ATP-dependent RNA helicase DDX39 DDX39_MOUSE

GAVGALLVYDIAK (82–94)

2

65

22,463

5.87

Down

NILTEIYR (166–173)/

2

ILVATNLFGR (338–348)

2

90

1243

Peroxiredoxin-2 PRDX2_MOUSE

GLFIIDAK (128–135)

2

106

21,457

4.76

Down

QITVNDLPVGR (140–150)

2

1364

ADP-ribosylation factor 1 ARFX_MOUSE^b

ILMVGLDAAGK (19–29)

2

50

17,059

6.80

Down

1430

Ubiquitin-conjugating enzyme E2 N UBE2N_MOUSE

LLAEPVPGIK (15–24)

2

107/128

15,088

6.53

Down

TNEAQAIETAR (131–141)

2

599

Actin-like protein 3 ARP3_MOUSE

YSYVCPDLVK (231–240)

2

97

46,669

6.25

Down

NIVLSGGSTMFR (318–329)

2

LSEELSGGR (349–357)

2

DYEEIGPSICR (399–409)

2

740

Heterogeneous nuclear ribonucleoprotein A/B ROAA_MOUSE

IFVGGLNPEATEEK (161–174)

2

113

40,104

7.11

Down

EVYQQQQYGSGGR (238–250)

2

1184

Transforming protein RhoA RHOA_MOUSE

LVIVGDGACGK (8–18)

2

79

23,410

6.82

Down

IGAFGYMECSAK (151–162)

2