Skip to main content

Table 1 Defense and immunity proteins

From: The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome

   Normalized Volumes Mean (SD) WTFA vs WTO3
p ≤ 0.05
Normalized Volumes Mean (SD) KOFA vs KOO3
p ≤ 0.05
WTFA vs KOFA
p ≤ 0.05
WTO3 vs KOO3
p ≤ 0.05
   WTFA WTO3   KOFA KOO3    
Adipsin (complement factor D) 2.05
(0.337)
2.43
(0.610)
  2.13
(0.742)
2.34
(0.655)
   
Alpha-1-antitrypsin 1-1 1.18
(0.191)
1.04
(0.102)
  1.35
(0.369)
0.94
(0.210)
   
Alpha 1-antitrypsin 1-6 2.15
(.230)
2.94
(0.353)
* 2.85
(0.484)
3.47
(0.712)
  *  
Annexin A1 3.05
(0.168)
2.57
(0.381)
.058 2.73
(0.409)
2.38
(0.517)
   
Annexin A5 1.10
(0.155)
1.30
(0.251)
  0.58
(0.078)
1.04
(0.171)
* *  
Antithrombin-III 3.08
(0.589)
4.54
(0.659)
* 3.53
(0.342)
4.78
(0.454)
*   
Apolipoprotein A-I 1.59
(0.300)
2.18
(0.350)
* 2.24
(0.668)
4.41
(1.038)
*   *
Chain A, Mammalian
Lectin Ym1
3.78
(1.000)
2.76
(0.290)
  3.03
(0.053)
1.97
(0.903)
.058   
Chia protein 1.20
(0.244)
0.88
(0.172)
.075 1.49
(0.367)
0.82
(0.354)
*   
Chitinase-3-like protein 1 precursor (GP-39) 11.19
(1.860)
7.35
(1.959)
* 9.26
(2.089)
4.46
(1.843)
*   
Complement
component C3
0.65
(0.142)
1.04
(0.212)
* 0.74
(0.248)
1.24
(0.261)
*   
Complement
component C5
7.26
(0.617)
6.88
(0.999)
  7.32
(0.692)
6.08
(0.766)
.053   
Esterase 1 2.73
(0.187)
3.85
(0.960)
* 3.31
(0.220)
4.44
(0.687)
* *  
Ferritin (light chain) 1.43
(0.325)
1.21
(0.180)
  1.34
(0.382)
1.13
(0.380)
   
Gluthathione S-transferase A4 (GST A4-4) 1.41
(0.153)
0.80
(0.445)
* 1.32
(0.148)
0.65
(0.146)
*   
Glutathione S-transferase omega 1 3.52
(0.140)
2.78
(0.416)
* 2.94
(0.422)
2.77
(0.986)
  * *
Haptoglobin 12.71
(2.040)
11.21
(0.835)
  11.47
(0.326)
7.61
(0.764)
*   
Heat shock protein 1, alpha 0.75
(0.092)
0.95
(0.114)
* 0.70
(0.164)
0.95
(0.076)
*   
Heat shock protein 70 3.93
(0.807)
5.82
(1.173)
* 4.64
(0.556)
7.79
(1.026)
*   
Kininogen 1 5.36
(1.723)
6.99
(0.703)
  5.89
(0.514)
7.65
(0.456)
*   
Lactate dehydrogenase 2, B chain 1.26
(0.417)
1.03
(0.520)
  1.05
(0.179)
0.84
(0.062)
.072   
Murinoglobulin-1 precursor (MuG1) 0.77
(0.166)
1.07
(0.136)
* 0.88
(0.073)
1.26
(0.131)
*   
Peroxiredoxin 6 (Antioxidant protein 2) 5.60
(0.884)
3.35
(1.694)
.057 5.39
(0.486)
3.11
(0.667)
*   
Plasminogen 8.39
(1.194)
7.35
(0.653)
  8.82
(0.775)
7.70
(2.054)
   
Pregnancy zone protein 0.76
(0.166)
0.83
(0.059)
  0.94
(0.343)
1.05
(0.080)
   
Prothrombin precursor
(EC 3.4.21.5)
1.42
(0.171)
2.01
(0.423)
* 1.56
(0.167)
2.15
(0.301)
*   
Pulmonary surfactant-assoc. protein A (SP-A) 36.21
(7.512)
29.07
(6.055)
  - '-   *  
Selenium binding protein 1 1.42
(0.177)
0.83
(0.402)
* 1.39
(0.212)
0.68
(0.105)
*   
Selenium binding protein 2 5.61
(0.794)
3.53
(1.407)
* 5.33
(0.742)
3.00
(0.472)
*   
Similar to Glutathione S-transferase Ya chain 1.53
(0.166)
0.94
(0.443)
* 1.43
(0.174)
0.83
(0.216)
*   
  1. The proteins assigned to the defense and immunity category (DEF) are listed (n = 30). An arrow indicates whether levels of expression are increased (↑) or decreased (↓) in response to ozone. The mean values for the normalized volumes and standard deviations for each named protein are given for WTFA, WTO3, KOFA, and KOO3. The asterisk indicates whether the p-value for the comparisons of WTFA vs. WTO3; KOFA vs. KOO3; WTFA vs. KOFA; and WTO3 vs. KOO3 was ≤ 0.05. Values that were slightly above 0.05 are also given.