Table 1 Protein expression changes induced by TGF-β (24 hour treatment) in BRI-JM01 cells, identified by WGA affinity workflow.
BR1 | BR2 | BR3 | ||||
|---|---|---|---|---|---|---|
Swiss-Prot | # pept | ratio 1 ± SD | # pept | ratio ± SD | # pept | ratio ± SD |
UP-REGULATED | ||||||
Q06890 |CLUS_MOUSE Clusterin precursor | ||||||
9 | 4.21 ± 0.51 | 7 | 4.26 ± 0.17 | 3 | 4.25 ± 0.45 | |
P11276 |FINC_MOUSE Fibronectin precursor (FN) | ||||||
7 | 1.85 ± 0.37 | 8 | 1.63 ± 0.69 | 3 | 1.92 ± 0.57 | |
P11688 |ITA5_MOUSE Integrin alpha-5 | ||||||
2 | 1.41 ± 0.21 | 2 | 1.97 ± 0.16 | 1 | 9.93 ± 1.33 | |
NP_997551.1 | Acid phosphatase, prostate isoform 1 [NP_062781.2] | ||||||
1 | 1.40 ± 0.17 | 1 | 1.49 ± 0.21 | 0 | -- | |
O70309 |ITB5_MOUSE Integrin beta-5 | ||||||
2 | 1.39 ± 0.14 | 2 | 0.99 ± 0.16 | 2 | 1.55 ± 0.10 | |
NP_058085.1 | Heterogeneous nuclear ribonucleoprotein U | ||||||
2 | 1.36 ± 0.6 | 2 | 1.37 ± 0.27 | 0 | -- | |
P63260 |ACTG_MOUSE Actin, cytoplasmic 2 [P60710] | ||||||
8 | 1.34 ± 0.21 | 10 | 1.13 ± 0.08 | 6 | 1.62 ± 0.08 | |
DOWN-REGULATED | ||||||
Q9QZM0 |UBQL2_MOUSE Ubiquilin-2 | ||||||
1 | 0.91 ± 0.71 | 3 | 0.69 ± 0.08 | 1 | 0.64 ± 0.16 | |
Q8R143 |PTTG_MOUSE Pituitary tumor-transforming gene 1 | ||||||
2 | 0.80 ± 0.05 | 2 | 0.70 ± 0.04 | 0 | -- | |
P35951 |LDLR_MOUSE Low-density lipoprotein receptor precursor | ||||||
1 | 0.62 ± 0.11 | 1 | 0.71 ± 0.06 | 0 | -- | |
Q61739 |ITA6_MOUSE Integrin alpha-6 | ||||||
13 | 0.57 ± 0.08 | 13 | 0.79 ± 0.04 | 4 | 0.87 ± 0.03 | |
NP_598424.2 | Integrin beta 4 | ||||||
15 | 0.56 ± 0.08 | 15 | 0.84 ± 0.05 | 3 | 0.98 ± 0.22 | |
NP_064431.2 | tumor-associated calcium signal transducer 2 | ||||||
2 | 0.51 ± 0.12 | 2 | 0.57 ± 0.05 | 0 | -- | |