Figure 7From: Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix Proteomic and Phenotypic profiles of A9 and WA17 cell lines. (A) WA17 and A9 cell lines were grown in presence (n = 14 experiments for each cell line) or absence (n = 4 experiments for each cell line) of Col VI or FN and protein profiles were generated by SELDI-TOF MS using the Q10 array. A correlation biplot of PCA components 1 and 2 is shown (CiphergenExpress software). (B) Plates were coated or not coated with FN or Col VI. Cell adhesion was analyzed on the X axis (n = 12 experiments for each data point) and cell proliferation on the Y axis (n = 12 experiments for each data point). Adhesion and proliferation assays were performed in the same conditions as for the data in figure 3.Back to article page