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Figure 3 | Proteome Science

Figure 3

From: Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling

Figure 3

Comparison serum profiles PR vs. no PR. A, five differential peaks in the comparison between PR (red) versus PD+SD (blue) using pre-treatment samples. Five randomly selected in the same comparison. Each overlay contains spectra with normalized intensities. B, Kaplan-Meier (1) time to progression and (2) overall survival curve in NSCLC patients, by prediction of PR or no PR, using the 5-peptide signature (intent-to-treat population, n = 27). C, median of the five differential peaks in the comparison between PR (red) versus PD+SD (blue) using three time points: pre-treatment (PreTx), after two cycles of treatment (Post-2), and at end of treatment (EOT). D, Kaplan-Meier (1) time to progression and (2) overall survival curve in NSCLC patients, by prediction of PR or no PR, using the 10-peptide signature (intent-to-treat population, n = 27).

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Proteome Science

ISSN: 1477-5956