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Table 7 Comparison serum profiles NSCLC vs. cancer-free controls

From: Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling

m/z

p-value

peptide ID

1777.966

2.18E-06

C3f

1877.9926

9.96E-06

 

1545.616

2.49E-05

 

1690.9254

2.83E-05

C3f

1865.0022

2.83E-05

C3f

1039.6249

4.67E-05

 

1361.7417

5.97E-05

 

880.4127

7.62E-05

 

1041.6349

0.00010908

 

1955.9949

0.00013801

 

1015.6267

0.00017407

 

1087.5722

0.00017407

 

1063.6231

0.00034269

 

1092.5826

0.00034269

 

2318.2202

0.00034269

 

2536.2991

0.00034269

 

2105.4972

0.00047573

 

1396.5679

0.0005897

 

2112.022

0.00072868

 

987.5905

0.0013492

 

1616.6366

0.0016465

P-FPA

2324.1475

0.0018167

C3 beta

2104.998

0.0022066

 

2153.0655

0.0024291

 

1450.4893

0.0026719

 

2193.1036

0.0032253

C3 beta

898.4169

0.0035395

 

3427.8221

0.0035395

 

2163.9817

0.0046562

 

1670.5947

0.0050941

 

2099.1139

0.0072417

 

1456.5093

0.0078632

 

1418.539

0.0078923

 

1630.6679

0.0078923

 

2228.0362

0.0078923

 

2209.0934

0.0085948

**

3326.6863

0.0085948

Hb alpha

1434.5136

0.01017

 

3473.7545

0.01017

Hb alpha

1432.644

0.014108

 

1292.4157

0.01933

 

1440.5407

0.024299

 

2246.1744

0.030331

 

2789.0914

0.032609

 

3156.6207

0.035032

ITIH4

1276.456

0.037607

 

1458.4946

0.040342

 
  1. 47 peaks were significantly differential comparing NSCLC patients and healthy volunteers. Ordered by p-value. ** identified by Tempst et al. as high-molecular-weight kininogen [19]. Abbreviations: P-FPA: phospho-fibrinopetide A; C3 beta/f: complement C3 beta/f; Hb alpha: hemoglobin alpha; seAlb: serum albumen; ITIH4: inter-alpha-trypsin inhibitor heavy chain H4