Skip to main content

Table 1 Clinical data of the diabetic patients differentiated according to level of albuminuria

From: Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy

 

N

MIC

DMN

p value

n, total

42

40

41

 

Gender, Male (female)

19 (23)

18 (22)

22 (19)

0.25

Age (years)

56 (11)

55 (11)

49 (10)*

0.01

DM duration (years)

36 (11)

36 (11)

34 (10)

0.58

BMI (kg/m2)

24.5 (2.8)

25.2 (3.7)

25.3 (4.5)

0.62

HbA1c (%)

8.2 (1)

8.8 (1.2)

8.9 (1.1)*

0.02

Creatinine (μmol/l)◆

91 (82-96)

90 (81-102)

124 (99-172)* ,§

<0.0001

U-albumin (mg/g)◆¶

6 (4-8)

23 (9-59)

453 (195-936) * ,§

<0.0001

eGFR(ml/min/1.73 m2)

70.1 (10.7)

68.6 (11.4)

49.5 (18.5) * ,§

<0.0001

Cholesterol (mmol/l)

4.8 (0.8)

5 (1)

4.9 (1)

0.55

Systolic BP (mmHg)

138 (23)

140 (23)

144 (19)

0.42

Diastolic BP (mmHg)

74 (10)

73 (12)

78 (10)

0.09

  1. Numbers are presented as mean (SD). ◆ Numbers are presented as median (IQR). ¶ Some patients had U-albumin levels reduced by antihypertensive medication which was not stopped when spot urine samples were collected for the study.
  2. * Indicates that means differed significantly between DMN group and N group.
  3. § Indicates that means differed significantly between DMN group and MIC group.
  4. # Indicates that means differed significantly between MIC group and N group.
  5. n, numbers; DM, diabetes mellitus; HbA1c, hemoglobin A1c; U-albumin, urinary albumin levels normalized to creatinine levels; eGFR, estimated glomerular filtration rate; BP, blood pressure