Skip to main content

Table 3 Proteins found in both the LDL fraction and the HDL fraction.

From: Quantitative comparison of lipoprotein fractions derived from human plasma and serum by liquid chromatography-tandem mass spectrometry

 

LDL Fractions

HDL Fractions

Protein Description

Plasma Avg. Scan Count ± SEM

Serum Avg. Scan Count ± SEM

Plasma Avg. Scan Count ± SEM

Serum Avg. Scan Count ± SEM

Alpha-1 -antitrypsin

2 ± 0.97

0.4 ± 0.52

39.8 ± 33.3

41 ± 43.8

Alpha-2-macroglobulin

475 ± 166

753 ± 171

11.1 ± 7.7

37.6 ± 38†

Serum Albumin

5.8 ± 5

7 ± 5.4

324.5 ± 243.4

306.1 ± 221.1

Alpha-1-microglobulin

0

0.4 ± 0.9

2.3 ± 1.1

2.3 ± 1.1

Apolipoprotein A-I

9 ± 2.2

11 ± 2.3

123.1 ± 30

107.2 ± 42

Apolipoprotein A-II

2.5 ± 1

3.2 ± 1

24.2 ± 6.5

26.7 ± 11.1

Apolipoprotein B-100

98 ± 19

167 ± 94†

0.44 ± 0.42

0.56 ± 0.30

Apolipoprotein C-III

5.7 ± 3.4

11.2 ± 8.8

1.9 ± 0.61

1.7 ± 0.58

Apolipoprotein E

4.8 ± 2.5

7.4 ± 2.7

1.8 ± 0.81

1.2 ± 1

Apolipoprotein-L1

2.3 ± 0.94

3 ± 1

0.78 ± 0.38

0.33 ± 0.29

Complement C1 s subcomponent

0.33 ± 0.3

0.8 ± 0.48

0.56 ± 0.3

0.78 ± 0.75

C4b-binding protein

17.5 ± 6.1

36 ± 28†

0

0.33 ± 0.41

Complement factor H

3. 5 ± 2.9

6.8 ± 6.1

5.7 ± 5.4

6.6 ± 4.7

Apolipoprotein J (Clusterin)

2.3 ± 0.79

2.8 ± 2.1

2.6 ± 0.65

2.9 ± 1.3

Complement C4-A

1.7 ± 1

0.2 ± 0.25

38.8 ± 14.7

34.2 ± 16

Coagulation factor XIII B chain

0.67 ± 0.47

0

0

0.44 ± 0.42

Fibrinogen alpha chain

133.7 ± 35.3 *

0

1.1 ± 1.1

0

Fibrinogen beta chain

149.2 ± 21 *

0

2 ± 1.7 *

0

Fibrinogen gamma chain

143 ± 28 *

0

0.78 ± 0.9

0

Fibronectin

57.2 ± 24

98.8 ± 38†

0.89 ± 0.79

0.44 ± 0.58

Haptoglobin

5.5 ± 4

19.2 ± 15.3†

11.3 ± 9.3

7 ± 4.1

Haptoglobin-related protein

19 ± 14

47.6 ± 33†

40.1 ± 28.8

29.4 ± 18

Inter-alpha-trypsin inhibitor heavy chain H2

0.5 ± 0.48

1.8 ± 1.25

7.6 ± 4.4

10.3 ± 6.8

Paraoxonase-1

0.5 ± 0.32

0.8 ± 1

2.7 ± 0.96

2.9 ± 1.1

Prothrombin

0

10.4 ± 2.1†

6.6 ± 4

4 ± 2.8

Vitronectin

0.5 ± 0.3

1.8 ± 1.1

4.1 ± 2.6

3.4 ± 1.7

  1. The average scan count ± SEM is provided for each protein identified in both the LDL and HDL fractions derived from plasma and serum. (P < 0.001; * significantly greater in plasma; †significantly greater in serum)