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Table 3 Proteins identified from FFPE tissues and that correspond to those differentially expressed in the adenoma of the fresh/frozen tissues.

From: Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands

Protein Name

Accession N°

Theoretical Mr/pI

Fold variation adenoma vs

normal in fresh frozen tissue *

LC/MS/MS from gel-based (A),

gel-free (B), or both (C)

Voltage-dependent anion selective channel protein1

P21796

31/8.6

↑ 5.1

B

Cytochrome c oxidase subunit5A, mitochondrial

P20674

17/6.3

↑ 7.8

B

Cytochrome b-cl complex subunit 1

P31930

53/5.9

↓ 2.0

B

Protein S100 - A11

P31949

12/6.6

↑ 2.9

A

Parkinson disease protein 7

B2R4Z1

20/6.3

↑3.4

B

Glyceraldehyde 3-phosphate dehydrogenase

P04406

36/8.6

↑ 2.5

C

Apolipoprotein A-I precursor

P02647

31/5.6

↓ 1.85

B

Ezrin

P15311

69/5.9

↑ 2.3

B

Parvalbumin

P20472

11/4.8

↑ 6.1

A

Serum albumin precursor

P02768

71/5.9

↓ 1.7

B

Serotransferrin precursor

P02787

79/6.8

↑ 2.1

C

Ubiquitin carrier protein (Fragment)

A8MUJ2

16/5.4

↑ 4.8

A

40S ribosomal proteín SA

P08865

33/4.8

↓ 1.7

B

Calmodulin

P62158

17/4.1

↑3.2

B

Annexin A5

P08758

36/4.9

↑ 2.7

B

14-3-3 zeta/delta

P63104

28/4.7

↑ 2.6

C

60 kDa heat shock protein, mitochondrial precursor

P10809

61/5.7

↑ 4.1

B

  1. *See reference 1