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Figure 5 | Proteome Science

Figure 5

From: Comparative Proteomic Analysis of saccharopolyspora spinosa SP06081 and PR2 strains reveals the differentially expressed proteins correlated with the increase of spinosad yield

Figure 5

Integrated proteome data onto a simplified metabolic network. I: TCA cycle; II: Glycolysis;III: SAM degradation pathway. Pathways and corresponding enzymes were identified from Swiss-Prot and TrEMBL databases, and only major reactions in each pathway are shown. Protein names are provided in Additional file 5: Table S6. Up or down arrows show the up- or down-regulation of proteins in PR2 strain, respectively. Abbreviations: PDGE1β, pyruvate dehydrogenase E1 component beta subunit; PEP, phosphoenolpyruvate; G6P, glucose-6-phosphate; RL5P, ribulose 5-phosphate; SAH, S-adenosyl-homocysteine; PFK, 6-phosphofructokinase; PK, pyruvate kinase; GAPDH, glyceraldehyde 3-phosphate dehydrogenase; MMSAD, methylmalonate semialdehyde dehydrogenase (acylating); GS, glutamine synthetase; CS, citrate synthase; ACAT, acetyl-CoA acetyltransferase; MHM, 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase; SCS, succinyl-CoA synthetase subunit alpha; UPS, uroporphyrinogen III synthetase; SAM, S-adenosylmethionine; PKS, polyketide synthase; L-Met, L-methionine; CoA, coenzyme A; NAD+, nicotinamide adenine dinucleotide; NADH, reduced form of nicotinamide adenine dinucleotide; NADP+, nicotinamide adenine dinucleotide phosphate; NADPH, reduced form of nicotinamide adenine dinucleotide phosphate.

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