Identification of stromal proteins overexpressed in nodular sclerosis Hodgkin lymphoma

Table 2 Clinico-pathological characteristics of the nodular sclerosis Hodgkin Lymphoma (HL) analysed in the study

								*Intensity of immunostaining*
n°	age	sex	size (cm)	nature of lymph node	CD30	CD15	EBV	Versican	Fibulin-1	Periostin
HL1	19	M	1,3	cervical	+	+	-	+++	+++	++*
HL2	45	M	1,7	cervical	+	+	+	++*	+	+++*
HL3	21	F	2,6	axillary	+	+	-	-/+	++*	++*
HL4	27	M	2,2	cervical	+	+/-	-	++*	++*	+++*
HL5	17	F	2,4	cervical	+	+	-	+++	+	++
HL6	16	F	1,6	jugular	+	-	-	+++	+++	+++
HL7	21	M	1,5	supraclavicular	+	-	-	+++	+++	+++
HL8	27	M	3,8	axillary	+/-	+/-	-	+++	+++	+++
HL9	29	M	1	cervical	+	+	-	+++	+++	+++
HL10	31	M	1,5	mediastinal	+	+	-	++	++	+++
HL11	19	F	2,5	cervical	+	+/-	-	++	++	+++
HL12	33	M	2,1	cervical	+	+/-	+	+++	+++	+++
HL13	37	F	2,5	supraclavicular	+	+/-	-	++	++	+++
HL14	22	F	0,8	cervical	+	+/-	-	+	-/+	+++
HL15	20	M	3,1	cervical	+	+/-	+	+	-	++
HL16	54	M	1	cervical	+	+	+	-/+	-	++
HL17	33	F	1	supraclavicular	+	+	-	+++	++	++

Scoring of the intensity of the staining for fibulin-1, periostin and versican was performed as described in the "Methods" section. Cases in bold were analysed by mass spectrometry (see Additional File 2). The asterisk indicates that the protein was also detected by mass spectrometry in the same sample.

ISSN: 1477-5956