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Figure 4 | Proteome Science

Figure 4

From: Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

Figure 4

Concordance of CEER with IHC in primary breast tumors. The distribution of HER2 expression based on CEER in each IHC sub-group are shown in (a). The quantitative distribution within each sub-group is shown in (c). There were 17% (38/227) discordant calls between IHC and CEER HER2 status (C - concordance, D - discordance). The outcome of IP-W analysis of 100 samples (including all with discordant calls) are summarized in (e). The concordance between CEER and IP-W adjusted HER status are shown in (b) and (d). Representative IP-W images for each sub-group are shown in (e).

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