Statistical analysis of 2D DIGE results. The figure illustrates the heat map (a) and the score plot (b) obtained upon comparison of the serum protein profiles of sea breams at T12A (pink) and T12B (green). In the heat map (a), each cell represents the differential protein expression trend, indicating increased expression in green and decreased expression in red. Clustering is performed according to the proteins (left dendrogram) and the sample (top dendrogram). In the score plot (b), sample clustering according to the principal component analysis is reported.