Table 1 Identification of differentially expressed protein spots in VL
From: Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis
Spot no. | Protein name | Accession no | pI | MW in KDa | score | % of SCa | VL/ECb | VL/NECb | Expression |
|---|---|---|---|---|---|---|---|---|---|
pI range 4-7 | |||||||||
1 | Unidentified | — | ~6.5 | ~15 | — | — | 7.51 | 4.32 | ↑ |
2 | Unidentified | — | ~6.0 | ~15 | — | — | 27.08 | 18.31 | ↑ |
3 | Unidentified | — | ~5.5 | ~15 | — | — | 26.57 | 17.32 | ↑ |
4 | Unidentified | — | ~5.0 | ~15 | — | — | 18.82 | 15.39 | ↑ |
5 | Amyloid A1 precursor | YLHUS | 6.28 | 13.58 | 80 | 52 | 9.14 | 7.21 | ↑ |
6 | Amyloid A1 precursor | YLHUS | 6.28 | 13.58 | 89 | 53 | 8.04 | 6.10 | ↑ |
7 | Unidentified | — | — | — | — | — | 2.66 | 2.01 | ↑ |
pI range 4.7-5.9 | |||||||||
1 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 230 | 36 | 2.63 | 2.12 | ↑ |
2 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 240 | 49 | 7.49 | 6.32 | ↑ |
3 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 230 | 36 | 11.29 | 9.21 | ↑ |
4 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 250 | 54 | 7.41 | 6.37 | ↑ |
5 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 230 | 36 | 5.58 | 5.60 | ↑ |
6 | a-1-antitrypsin precursor | ITHU | 5.37 | 46.88 | 392 | 55 | 4.30 | 4.50 | ↑ |
8 | Vitamin-D binding protein | VYHUD | 5.40 | 54.53 | 243 | 45 | -3.94 | -3.21 | ↓ |
9 | Fibrinogen gamma-B chain precursor | FGHUGB | 5.37 | 52.11 | 149 | 53 | 2.73 | 1.89 | ↑ |
10 | Fibrinogen gamma-B chain precursor | FGHUGB | 5.37 | 52.11 | 148 | 53 | 2.68 | 1.93 | ↑ |
11 | APO A-I protein (frag.) | CAA00975 | 5.27 | 28.06 | 390 | 56 | -3.31 | -2.93 | ↓ |
12 | Transthyretin | 2ROYA | 5.35 | 13.24 | 272 | 85 | -3.96 | -3.53 | ↓ |
13 | Unidentified | — | ~5.30 | ~30-45 | — | — | 4.93 | 3.97 | ↑ |
14 | Unidentified | — | ~5.30 | ~30-45 | — | — | 6.30 | 5.32 | ↑ |
15 | Unidentified | — | ~5.30 | ~30-45 | — | — | 5.60 | 4.73 | ↑ |
16 | Unidentified | — | ~5.30 | ~30-45 | — | — | 5.83 | 4.98 | ↑ |
17 | Unidentified | — | ~5.30 | ~30-45 | — | — | 4.88 | 4.54 | ↑ |
18 | APO A-IV protein | LPHUA4 | 5.23 | 45.30 | 280 | 54 | -4.82 | -4.00 | ↓ |
19 | APO A-I protein | CAA975 | 5.27 | 28.06 | 242 | 62 | -2.68 | -2.71 | ↓ |