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Table 2 Identification of VL associated differentially expressed glycoprotein spots

From: Comparative proteomics and glycoproteomics of plasma proteins in Indian visceral leishmaniasis

Spot no.

Protein name

Accession no

pI

MW in KDa

score

% of SCa

VL/ECb

VL/NECb

Expression

1

μ1-B glycoprotein

OMHU1B

5.65

52.48

112

34

2.24

2.01

↑

2

a1-B glycoprotein

OMHU1B

5.65

52.48

123

38

2.06

2.00

↑

4

Unidentified

—

~6.1

~38

—

—

2.01

1.92

↑

5

Haptoglobin precursor, allele-1

HPHU1

6.13

38.94

105

34

2.18

2.30

↑

6

Haptoglobin precursor, allele-1

HPHU1

6.13

38.94

157

34

2.39

2.49

↑

7

Haptoglobin precursor, allele-1

HPHU1

6.13

38.94

152

34

2.76

2.02

↑

8

Haptoglobin precursor, allele-2

HPHU2

6.13

45.86

68

24

3.68

3.69

↑

9

Haptoglobin precursor, allele-2

HPHU2

6.13

45.86

98

21

3.13

2.79

↑

10

Haptoglobin precursor, allele-2

HPHU2

6.13

45.86

117

28

3.81

2.67

↑

11

Unidentified

—

~5.5

~53

—

—

2.24

2.00

↑

12

Unidentified

—

~6.1

~38

—

—

2.87

2.65

↑

13

Haptoglobin precursor, allele-1

HPHU1

6.13

38.94

138

37

3.43

2.57

↑

14

Unidentified

—

~6.1

~45

—

—

3.60

2.97

↑

15

Unidentified

—

~6.2

~25

—

—

-3.12

-2.78

↓

  1. Differentially expressed glycoprotein spots were identified by MALDI-TOF/TOF mass spectrometry. Combined MS and MS/MS results were analyzed by MASCOT and fold of up/down regulation were determined from DIA analysis.
  2. aSC- Sequence-coverage.
  3. bFold of increase and decrease ratio of the differentially expressed proteins from DIA analysis using DeCyder software from three different 2D-DIGE experiments with significant p< 0.05 were reported.
  4. EC- endemic control.
  5. NEC- non-endemic control.
  6. ↑- Up-regulation.
  7. ↓- Down-regulation.