Serum peptidome based biomarkers searching for monitoring minimal residual disease in adult acute lymphocytic leukemia

Table 1 Different expressed peptides between newly diagnosed ALL and healthy controls

Index	Mass	Dave	PWKW	Ave1	Ave2	StdDev1	StdDev2	Expression Change
61	9288.31	2.32	< 0.000001	1.31	3.63	0.28	1.87	↓
27	3443.92	1.1	< 0.000001	1.54	2.64	0.66	0.9	↓
41	4249.06	0.76	0.000007	1.7	2.46	0.62	0.49	↓
13	2661.27	20.95	< 0.000001	28.39	7.44	22.56	3.69	↑
43	4645.31	1.74	0.00000373	1.67	3.41	1.09	1.75	↓
7	1945.51	1.06	0.00000114	2.01	3.06	0.39	1.12	↓
8	2093.83	1.15	0.0000791	3.38	2.23	1.38	0.44	↑
33	4072.42	0.4	0.00175	1.59	1.99	0.43	0.4	↓
35	4108.67	0.45	0.00129	1.66	2.1	0.53	0.41	↓
28	3884.26	0.85	0.000281	1.65	2.5	0.82	1.02	↓
4	1546.94	5.98	0.000942	10.48	4.5	8.72	2.57	↑
12	2644.19	0.86	0.001	2.93	2.07	1.23	0.5	↑
36	4123.33	0.42	0.00445	1.7	2.13	0.54	0.43	↓
62	9367.9	1.28	0.0108	0.95	2.23	0.41	1.2	↓
11	2561.9	1.28	0.000009	3.07	1.79	1.97	0.49	↑
21	2991.46	5.28	< 0.000001	17.24	1.96	8.54	0.63	↑
34	4091.61	1.46	0.00622	3.16	4.62	1.55	1.93	↓
58	7764.29	1.3	0.00000217	1.39	2.68	0.7	1.44	↓
10	2545.82	0.92	0.00619	2.98	2.06	1.53	0.47	↑
46	5064.98	0.33	0.0374	1.11	1.44	0.27	0.53	↓
2	1466.84	5.01	0.000639	8.46	3.46	4.84	2.44	↑
1	1450.14	1	0.0163	4.09	3.1	1.72	0.68	↑
57	7025.82	0.69	0.00913	0.83	1.52	0.35	1.23	↓
14	2673.64	1.7	0.00626	4.04	2.34	1.22	0.53	↑
42	4266.78	1	0.0154	2.56	3.57	1.22	1.6	↓
18	2900.77	0.89	0.0288	2.62	1.74	1.71	0.48	↑
5	1618.2	3.56	0.0000421	6.76	3.19	4.43	1.65	↑
3	1526.98	1.92	0.0107	4.29	2.37	2.03	0.61	↑
38	4169.26	0.43	0.0146	2.04	2.46	0.81	0.54	↓
39	4194.35	0.71	0.0173	2.88	3.59	1.35	1.01	↓
29	3891.28	0.44	0.0285	1.83	0.77	0.86	0.17	↓
22	3192.79	0.38	0.00906	2.03	2.4	1.19	0.78	↓
25	3263.65	0.84	0.00446	2.98	3.82	1.7	1.75	↓

Index: Peptide peak index; Mass: Mass to charge ratio value; Dave: Differences of average peak intensity between newly diagnosed ALL group and healthy control group; P value: p value of Wilcoxon test; Ave1: Average peak intensity of newly diagnosed ALL group; Ave2: Average peak intensity of healthy control group; StdDev1: Standard deviation of the peak intensity average of newly diagnosed ALL group; StdDev2: Standard deviation of the peak intensity average of healthy control group.

ISSN: 1477-5956