Figure 6
Comparison of found protein accessions across the Paca44 samples with the ToppGene Suite functional analyses. The enrichment of the CD molecules, small GTP binding proteins as well as annexins were overrepresented in the affinity pure samples, and the released proteins derived from the ribosomes, proteasomes and tubulins were reduced. *1#899 Paca44 proteins were enriched in the secretome, calculated by filtering with fold change (FC) crude EV/secretome < 0.7; *2#183 Paca44 proteins were enriched in exosome crude samples filtered by FC crude EV/secretome >4.3; *3#342 Paca44 proteins were enriched in affinity purified exosomes filtered by FC affinity pure/crude >1.5 and FC affi pure/secretome > 3; the criteria for analyses are given in Additional file 1: Figure S6.