Figure 7

Top50 proteins enriched in Paca44 affinity pure EV samples in comparison to crude samples and secretomes. The groups of proteins were selected by fold change FC affinity pure/crude >1.3 and FC affinity pure/secretome > 3, and measured with the minimal 2 peptides. The number of peptides measured in each sample was corrected and normalized as described in the Materials and Methods. The proteins marked with asterisks were tested by specific antibodies in the immune blots (see Additional file 1: Figure S8).