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Table 1 Enriched KEGG pathways analysis

From: Proteomic study of different culture medium serum volume fractions on RANKL-dependent RAW264.7 cells differentiating into osteoclasts

Pathway name

Gene

EntrezGene

Statistics

Huntington's disease

9

12858 11740 22335 66142 67264 14775 17709 22333 20463

C = 197;O = 9;E = 0.27;R = 33.89;rawP = 7.62e-12;adjP = 1.37e-10

Parkinson's disease

8

12858 11740 22335 66142 67264 17709 22333 20463

C = 148;O = 8;E = 0.20;R = 40.10;rawP = 3.05e-11;adjP = 2.75e-10

Metabolic pathways

13

12858 56012 18263 # 14085 # 18770 # 66142 13200 208715 # 67264 27425 20018 # 110196 # 17709

C = 1184;O = 13;E = 1.60;R = 8.14;rawP = 6.66e-09;adjP = 4.00e-08

Oxidative phosphorylation

6

67264 12858 27425 17709 66142 20463

C = 147;O = 6;E = 0.20;R = 30.28;rawP = 5.36e-08;adjP = 2.41e-07

Cardiac muscle contraction

4

12858 17709 66142 20463

C = 81;O = 4;E = 0.11;R = 36.63;rawP = 4.70e-06;adjP = 1.69e-05

Alzheimer's disease

5

67264 12858 17709 66142 20463

C = 188;O = 5;E = 0.25;R = 19.73;rawP = 5.98e-06;adjP = 1.79e-05

  1. •C: the number of reference genes in the category.
  2. •O: the number of genes in the gene set and also in the category.
  3. •E: the expected number in the category.
  4. •R: ratio of enrichment.
  5. •rawP: P-value from hypergeometric test.
  6. •adjP: P-value adjusted by the multiple test adjustment.
  7. •#: the genes upregulated.
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