Fig. 3

Piecewise baseline subtraction of a proteomic MALDI-TOF mass spectrum from the Fiedler dataset using the top-hat operator. An example of piecewise top-hat baseline estimation where the x-axis is shown as a the sequential number of the m/z point of the 42,388 m/z points, and b the m/z location. The window size of the top-hat operator is provided as a number of m/z points. Since the spacing of m/z values increases along the x-axis in (b), the SE size is not constant within sub-intervals of the m/z-axis