Table 1 A. Echocardiographic and B. Morphometric analysis of the left ventricle after four weeks on prescribed diet and morphometric measurements
From: Sex impacts cardiac function and the proteome response to thyroid hormone in aged mice
A | Baseline M CON | Final M CON | Baseline M PTU | Final M PTU | Baseline M TH | Final M TH | Baseline F CON | Final F CON | Baseline F PTU | Final F PTU | Baseline F TH | Final F TH |
| Â | N = 6 | N = 7 | N = 6 | N = 8 | N = 6 | N = 8 | ||||||
EDD, mm | 3.9±0.1 | 4.1±0.1 | 4.3±0.07 | 4.1±0.1 | 4.0±0.2 | 4.4±0.09 | 4.0±0.07 | 3.9±0.07 | 3.9±0.09 | 4.0±0.06 | 3.8±0.1 | 4.0±0.08 |
ESD, mm | 2.8±0.2 | 3.1±0.1 | 3.3±0.09 | 3.2±0.1 | 3.0±0.2 | 3.3±0.1 | 3.0±0.1 | 3.0±0.08 | 2.9±0.1 | 3.1±0.07 | 2.8±0.2 | 2.8±0.09 |
EF, % | 50±3.6 | 47±3.4 | 48±2 | 46±2 | 53±3.7 | 48±2.6 | 49±3 | 45±2 | 49±2.4 | 45±2.7 | 54±3.7 | 57±2.1 |
FS, % | 25±2.2 | 24±2.1 | 24±1 | 22±.9 | 27±2.4 | 25±1.5 | 24±2 | 22±1.2 | 25±1.5 | 22±1.6 | 28±2.4 | 30±1.4 |
LVPWd, mm | 0.81±.03 | 0.9±0.05 | 0.86±0.04 | 0.78±0.04 | 0.89±0.03 | 1.3±0.08* | 0.88±0.05 | 0.96±-.04 | 0.93±0.07 | 0.81±0.06 | 0.9±0.07 | 1.2±0.08* |
HR, BPM | 480±18 | 498±23 | 455±17 | 371±17** | 482±21 | 585±21** | 474±18 | 514±11 | 471±15 | 417±17 | 504±17 | 597±12** |
B | Baseline M CON | Final M CON | Baseline M PTU | Final M PTU | Baseline M TH | Final M TH | Baseline F CON | Final F CON | Baseline F PTU | Final F PTU | Baseline F TH | Final F TH |
| Â | N = 8 | N = 8 | N = 8 | N = 9 | N = 9 | N = 9 | ||||||
BW, g | 35±0.7 | 35±0.8 | 35±0.9 | 31±0.6** | 34±0.9 | 33±0.6 | 29±0.6 | 30±1 | 26±0.7 | 25±0.3 | 26±0.7 | 29±1** |
HW, mg | n/a | 169±9 | n/a | 137±6# | n/a | 246±6## | n/a | 146±4 | n/a | 115±3## | n/a | 223±10## |
HW/TL (mg/mm) | n/a | 9.7±0.6 | n/a | 8.0±0.3# | n/a | 14±0.4## | n/a | 8.3±0.2 | n/a | 6.7±.2## | n/a | 13±0.5## |