Table 3 Enriched gene ontology (GO) terms for molecular function and KEGG pathway of identified proteins

Molecular Function

GO:0051287~NAD binding

35.91

6.00E-07

1.09E-04

1.09E-04

7.41E-04

GO:0016491~oxidoreductase activity

6.54

1.30E-06

2.36E-04

1.18E-04

1.60E-03

GO:0016616~oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

41.15

1.17E-04

0.02

0.01

0.14

GO:0008137~NADH dehydrogenase (ubiquinone) activity

37.62

1.53E-04

0.03

0.01

0.19

GO:0051539~4 iron, 4 sulfur cluster binding

32.92

2.28E-04

0.04

0.01

0.28

GO:0003954~NADH dehydrogenase activity

75.96

6.66E-04

0.11

0.02

0.82

GO:0051536~iron-sulfur cluster binding

20.57

9.15E-04

0.15

0.02

1.12

GO:0008092~cytoskeletal protein binding

19.36

0.001

0.18

0.02

1.34

GO:0000287~magnesium ion binding

8.15

0.003

0.43

0.05

3.71

GO:0050839~cell adhesion molecule binding

13.91

0.02

0.97

0.21

21.07

GO:0019899~enzyme binding

4.29

0.03

0.99

0.26

28.94

KEGG Pathway

mmu01100:Metabolic pathways

3.46

8.21E-09

4.93E-07

4.93E-07

8.23E-06

mmu01130:Biosynthesis of antibiotics

10.27

9.09E-09

5.46E-07

2.73E-07

9.11E-06

mmu05012:Parkinson's disease

11.06

9.14E-07

5.49E-05

1.83E-05

9.16E-04

mmu00190:Oxidative phosphorylation

10.54

7.29E-06

4.37E-04

1.09E-04

7.30E-03

mmu05010:Alzheimer's disease

8.28

3.52E-05

2.11E-03

4.23E-04

3.53E-02

mmu05016:Huntington's disease

7.43

7.04E-05

0.004

0.001

0.07

mmu01200:Carbon metabolism

9.51

3.42E-04

0.02

0.00

0.34

mmu00020:Citrate cycle (TCA cycle)

22.98

6.20E-04

0.04

0.00

0.62

mmu04932:Non-alcoholic fatty liver disease (NAFLD)

7.02

0.001

0.08

0.01

1.35

mmu01210:2-Oxocarboxylic acid metabolism

29.02

0.004

0.23

0.03

4.37

mmu04610:Complement and coagulation cascades

9.67

0.01

0.36

0.04

7.24

mmu04260:Cardiac muscle contraction

9.55

0.01

0.37

0.04

7.50

mmu01230:Biosynthesis of amino acids

9.43

0.01

0.38

0.04

7.76