Quantitative proteomics by iTRAQ-PRM based reveals the new characterization for gout

Chen, Guangqi; Cheng, Jiafen; Yu, Hanjie; Huang, Xiao; Bao, Hui; Qin, Ling; Wang, Ling; Song, Yaxiang; Liu, Xinying; Peng, Ai

doi:10.1186/s12953-021-00180-0

Proteome Science

Table 3 Selected 40 proteins to be verified by PRM

From: Quantitative proteomics by iTRAQ-PRM based reveals the new characterization for gout

Accession	Coverage	Unique peptide	AG/CTL	P value	HUA/CTL	P value	RG/CTL	P value	AG/HUA	P value
Q14520	38	18	1.17	0.02	1.00	0.94	1.00	0.93	0.86	0.04
O95445	62	10	1.30	<0.01	1.15	0.01	1.29	0.10	0.99	0.91
P0DJI9	50	4	2.61	0.13	1.02	0.91	1.15	0.36	0.44	0.15
P23528	45	8	1.52	<0.01	1.37	0.17	1.42	0.17	0.93	0.70
P14780	23	14	1.50	<0.01	1.04	0.69	1.25	0.02	0.84	<0.01
P55056	30	5	2.17	<0.01	1.76	<0.01	1.90	<0.01	0.88	0.20
P02768	84	61	0.51	<0.01	0.43	<0.01	0.51	<0.01	0.99	0.84
P00734	56	35	1.04	0.13	1.00	0.96	0.97	0.29	0.93	0.02
P43652	45	25	0.90	<0.01	0.98	0.12	1.04	0.08	1.16	<0.01
P05160	49	29	1.15	0.01	1.02	0.49	1.00	0.96	0.87	<0.01
P05546	44	20	0.97	0.49	1.03	0.65	0.84	0.03	0.87	0.01
P06681	38	22	1.17	0.05	0.89	0.12	0.98	0.83	0.84	0.02
P02763	51	11	1.21	0.19	0.76	0.29	0.72	0.22	0.60	0.12
P19652	44	10	0.99	0.88	0.59	0.01	0.51	0.01	0.51	0.01
P05164	34	20	2.15	<0.01	0.95	0.63	1.18	0.30	0.55	0.01
P29401	32	17	0.91	0.10	0.72	0.02	0.96	0.28	1.06	0.34
Q9UHG3	34	14	1.22	0.07	1.08	0.35	1.14	0.42	0.93	0.61
P14625	22	16	1.00	0.98	0.83	0.02	0.79	<0.01	0.79	0.01
P02790	72	33	0.91	<0.01	0.98	0.15	0.92	0.22	1.01	0.92
P08697	49	22	0.93	0.30	0.95	0.33	0.94	0.27	1.01	0.82
Q96PD5	44	17	0.87	0.05	0.90	0.03	0.99	0.93	1.14	0.12
P04278	50	13	0.60	<0.01	0.70	0.01	0.72	0.03	1.20	0.23
P51884	38	10	0.79	<0.01	0.94	0.04	0.87	0.03	1.10	0.14
P35908	42	15	0.76	0.32	0.87	0.58	0.88	0.70	1.17	0.56
Q03591	28	1	0.97	0.73	0.99	0.87	0.99	0.81	1.01	0.86
P22352	29	6	0.83	0.02	0.88	0.02	0.87	0.07	1.05	0.43
Q14624	49	38	1.19	0.22	1.37	0.20	1.15	0.39	0.96	0.80
P05155	31	19	1.01	0.63	1.04	0.60	0.84	0.01	0.83	0.01
P07358	41	18	1.01	0.81	1.00	0.90	1.01	0.78	1.00	0.98
P07996	29	29	1.59	0.03	1.78	0.01	1.52	0.02	0.96	0.76
P02760	42	11	1.06	0.50	1.10	0.24	1.06	0.50	1.00	0.98
P02671	35	21	1.34	0.04	0.81	0.02	0.92	0.16	0.68	0.02
Q92954	20	23	1.33	0.02	1.18	0.01	1.13	0.04	0.85	0.10
O43866	47	17	1.66	0.02	0.92	0.47	1.12	0.09	0.68	0.05
P00915	57	10	1.06	0.63	1.42	0.22	2.19	0.02	2.06	0.03
Q04756	22	12	1.08	0.09	1.03	0.65	1.01	0.78	0.94	0.17
P00558	47	13	1.15	0.33	0.91	0.48	1.09	0.38	0.95	0.67
Q13201	16	14	1.20	0.08	1.10	0.34	1.17	0.19	0.97	0.76
O00187	17	9	1.18	0.06	0.97	0.70	1.09	0.23	0.93	0.01
P02741	23	5	1.73	0.11	0.71	0.32	1.35	0.41	0.78	0.41

The table shows the fold-change and its P-value of 40 selected proteins from iTRAQ data in four comparison groups. Accession refers to protein numbers in the FASTA Database. Coverage refers to the percentage of the protein sequence covered by identified peptides. Unique Peptides refers to the number of peptide sequences unique to a protein group

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