Table 1 List of differentially expressed proteins (foam cell/macrophage) located in the lysosome
From: TMT-based quantitative proteomic profiling of human monocyte-derived macrophages and foam cells
Protein accession | Protein description | Gene name | Fold change |
|---|---|---|---|
P13761 | HLA class II histocompatibility antigen, DRB1-7 beta chain | HLA-DRB1 | 11.602 |
P04114 | Apolipoprotein B-100 | APOB | 7.521 |
Q8N8Y2 | V-type proton ATPase subunit d 2 | ATP6V0D2 | 2.817 |
P13686 | Tartrate-resistant acid phosphatase type 5 | ACP5 | 2.518 |
P04066 | Tissue alpha-L-fucosidase | FUCA1 | 2.247 |
Q95IE3 | HLA class II histocompatibility antigen, DRB1-12 beta chain | HLA-DRB1 | 2.234 |
P20039 | HLA class II histocompatibility antigen, DRB1-11 beta chain | HLA-DRB1 | 2.107 |
Q86WA9 | Sodium-independent sulfate anion transporter | SLC26A11 | 2.067 |
P11279 | Lysosome-associated membrane glycoprotein 1 | LAMP1 | 2.002 |
Q9NX76 | CKLF-like MARVEL transmembrane domain-containing protein 6 | CMTM6 | 1.985 |
P43235 | Cathepsin K | CTSK | 1.884 |
P01909 | HLA class II histocompatibility antigen, DQ alpha 1 chain | HLA-DQA1 | 1.882 |
P27449 | V-type proton ATPase 16 kDa proteolipid subunit | ATP6V0C | 1.87 |
Q14108 | Lysosome membrane protein 2 | SCARB2 | 1.844 |
O15118 | NPC intracellular cholesterol transporter 1 | NPC1 | 1.786 |
P08962 | CD63 antigen | CD63 | 1.76 |
Q8N357 | Solute carrier family 35 member F6 | SLC35F6 | 1.748 |
P11117 | Lysosomal acid phosphatase | ACP2 | 1.705 |
P07339 | Cathepsin D | CTSD | 1.681 |
Q96AH8 | Ras-related protein Rab-7b | RAB7B | 1.677 |
P07686 | Beta-hexosaminidase subunit beta | HEXB | 1.674 |
P28068 | HLA class II histocompatibility antigen, DM beta chain | HLA-DMB | 1.67 |
P17900 | Ganglioside GM2 activator | GM2A | 1.619 |
Q96NW4 | Ankyrin repeat domain-containing protein 27 | ANKRD27 | 1.619 |
P15848 | Arylsulfatase B | ARSB | 1.597 |
Q30154 | HLA class II histocompatibility antigen, DR beta 5 chain | HLA-DRB5 | 1.582 |
P07711 | Cathepsin L1 | CTSL | 1.574 |
Q8IY95 | Transmembrane protein 192 | TMEM192 | 1.566 |
O00115 | Deoxyribonuclease-2-alpha | DNASE2 | 1.564 |
Q9Y2Q0 | Phospholipid-transporting ATPase IA | ATP8A1 | 1.553 |
Q9UHG3 | Prenylcysteine oxidase 1 | PCYOX1 | 1.539 |
Q13510 | Acid ceramidase | ASAH1 | 1.538 |
P06865 | Beta-hexosaminidase subunit alpha | HEXA | 1.518 |
P04440 | HLA class II histocompatibility antigen, DP beta 1 chain | HLA-DPB1 | 1.517 |
O00560 | Syntenin-1 | SDCBP | 1.51 |
P51688 | N-sulphoglucosamine sulphohydrolase | SGSH | 1.505 |
Q9GZY6 | Linker for activation of T-cells family member 2 | LAT2 | 0.572 |
A6NI72 | Putative neutrophil cytosol factor 1B | NCF1B | 0.53 |