Fig. 2
From: Profiles of transcriptome and metabolic pathways after hypobaric hypoxia exposure
Differentially expressed genes after Hypobaric Hypoxia treatment in HL-7702. A and B Relative mRNA and protein expression levels of PPARA and ANGPTL4 after hypobaric hypoxia treatment. PPARA was down-regulated after hypobaric hypoxia treatment and inhibited mostly at 24 h. ANGPTL was up-regulated after hypobaric hypoxia treatment and expressed at the highest level at 8 h. C Heatmap of differentially expressed genes after hypobaric hypoxia treatment. We obtained 528 and 765 significantly down- and up-regulated genes, respectively, in the hypobaric hypoxia treated samples. The heatmap results demonstrated our data has high reproducibility. The red frame represents the genes up-regulated by ANGPTL4