Venn diagrams of the protein datasets identified in mouse saliva. Two pools of female mice saliva (Female P1, Female P2) and 2 pools of male saliva (Male P1 and Male P2) were used in generating the Venn Diagram. Following the removal of duplicates, the datasets derived from the Female P1 and Female P2 were then combined, to generate a list of 256 proteins (Additional file 1). Further analysis revealed 154 proteins common to both pools of saliva. Similarly, datasets from the 2 male saliva pools were combined, resulting in a list of 263 proteins (Additional file 2). The compilation of data from Male P1 and Male P2 identified 159 proteins present in both samples. Datasets from the males and females were then combined to identify a total of 345 proteins: 174 proteins confirmed in datasets from both sexes as well as 82 proteins unique to the saliva from females and 89 unique to males (Additional file 3).