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  1. Enterococcus faecalis is an opportunistic pathogen and one of the most important causes of hospital infections. Bile acids are a major stress factor bacteria have to cope with in order to colonize and survive in...

    Authors: Liv Anette Bøhle, Ellen M Færgestad, Eva Veiseth-Kent, Hilde Steinmoen, Ingolf F Nes, Vincent GH Eijsink and Geir Mathiesen
    Citation: Proteome Science 2010 8:37
    Content type: Research Published on:

  2. Reverse phase protein arrays (RPPA) emerged as a useful experimental platform to analyze biological samples in a high-throughput format. Different signal detection methods have been described to generate a qua...

    Authors: Jan C Brase, Heiko Mannsperger, Holger Fröhlich, Stephan Gade, Christian Schmidt, Stefan Wiemann, Tim Beissbarth, Thorsten Schlomm, Holger Sültmann and Ulrike Korf
    Citation: Proteome Science 2010 8:36
    Content type: Methodology Published on:

  3. Proteomic analysis of laticifer latex in Hevea brasiliensis has been received more significant attentions. However, the sticky and viscous characteristic of rubber latex as cytoplasm of laticifer cells and the co...

    Authors: Xuchu Wang, Minjing Shi, Xiuli Lu, Ruifeng Ma, Chenggong Wu, Anping Guo, Ming Peng and Weimin Tian
    Citation: Proteome Science 2010 8:35
    Content type: Methodology Published on:

  4. Surfactant protein-A (SP-A) has been shown to play a variety of roles related to lung host defense function. Mice lacking SP-A are more susceptible to infection than wild type C57BL/6 mice. We studied bronchoa...

    Authors: Mehboob Ali, Todd M Umstead, Rizwanul Haque, Anatoly N Mikerov, Willard M Freeman, Joanna Floros and David S Phelps
    Citation: Proteome Science 2010 8:34
    Content type: Research Published on:

  6. Protein-based microarray platforms offer considerable promise as high-throughput technologies in proteomics. Particular advantages are provided by self-assembling protein microarrays and much interest centers ...

    Authors: Xristo Zárate, David C Henderson, Keenan C Phillips, April D Lake and David W Galbraith
    Citation: Proteome Science 2010 8:32
    Content type: Methodology Published on:

  7. Ovarian cancer is the most lethal gynecologic malignancy, with the majority of cases diagnosed at an advanced stage when treatments are less successful. Novel serum protein markers are needed to detect ovarian...

    Authors: Kristin LM Boylan, John D Andersen, Lorraine B Anderson, LeeAnn Higgins and Amy PN Skubitz
    Citation: Proteome Science 2010 8:31
    Content type: Research Published on:

  8. Shigella flexneri is a gram-negative, facultative pathogen that causes the majority of communicable bacterial dysenteries in developing countries. The virulence factors of S. flexneri have been shown to be produ...

    Authors: Ge Zhao, Li Zhu, Erling Feng, Xiaoyu Cao, Na Shang, Xiankai Liu, Xiang Liao, Tianyi Ying, Jie Wang, Huipeng Chen and Hengliang Wang
    Citation: Proteome Science 2010 8:30
    Content type: Research Published on:

  9. Infectious bronchitis virus (IBV) is the coronavirus of domestic chickens causing major economic losses to the poultry industry. Because of the complexity of the IBV life cycle and the small number of viral st...

    Authors: Qingming Kong, Chunyi Xue, Xiangpeng Ren, Chengwen Zhang, Linlin Li, Dingming Shu, Yingzuo Bi and Yongchang Cao
    Citation: Proteome Science 2010 8:29
    Content type: Research Published on:

  10. Hepatitis B virus (HBV) is a major cause of liver infection in human. Because of the lack of an appropriate cell culture system for supporting HBV infection efficiently, the cellular and molecular mechanisms o...

    Authors: Yanfeng Zhao, Haijing Ben, Su Qu, Xinwen Zhou, Liang Yan, Bin Xu, Shuangcheng Zhou, Qiang Lou, Rong Ye, Tianlun Zhou, Pengyuan Yang and Di Qu
    Citation: Proteome Science 2010 8:28
    Content type: Research Published on:

  11. Osteoarthritis (OA) is characterized by degeneration of articular cartilage. Animal models of OA induced are a widely used tool in the study of the pathogenesis of disease. Several proteomic techniques for sel...

    Authors: Elizabeth Pérez, José L Gallegos, Leticia Cortés, Karla G Calderón, José C Luna, Febe E Cázares, María C Velasquillo, Juan B Kouri and Fidel C Hernández
    Citation: Proteome Science 2010 8:27
    Content type: Research Published on:

  12. Flavobacterium columnare causes columnaris disease in cultured and wild fish populations worldwide. Columnaris is the second most prevalent bacterial disease of commercial channel catfish industry in the United ...

    Authors: Pradeep R Dumpala, Nagihan Gülsoy, Mark L Lawrence and Attila Karsi
    Citation: Proteome Science 2010 8:26
    Content type: Research Published on:

  13. Metamorphosis in the bryozoan Bugula neritina (Linne) includes an initial phase of rapid morphological rearrangement followed by a gradual phase of morphogenesis. We hypothesized that the first phase may be indep...

    Authors: Yue Him Wong, Shawn M Arellano, Huoming Zhang, Timothy Ravasi and Pei-Yuan Qian
    Citation: Proteome Science 2010 8:25
    Content type: Research Published on:

  14. Often high-quality MS/MS spectra of tryptic peptides do not match to any database entry because of only partially sequenced genomes and therefore, protein identification requires de novo peptide sequencing. To ac...

    Authors: Stephan Jung, Claudia Fladerer, Frank Braendle, Johannes Madlung, Otmar Spring and Alfred Nordheim
    Citation: Proteome Science 2010 8:24
    Content type: Research Published on:

  15. Gel-based proteomic is the most popular and versatile method of global protein separation and quantification. This is a mature approach to screen the protein expression at the large scale, and a cheaper approa...

    Authors: François Chevalier
    Citation: Proteome Science 2010 8:23
    Content type: Review Published on:

  16. Poly(ADP-ribose) polymerases (PARPs) catalyze the formation of poly(ADP-ribose) (pADPr), a post-translational modification involved in several important biological processes, namely surveillance of genome inte...

    Authors: Maxim Isabelle, Xavier Moreel, Jean-Philippe Gagné, Michèle Rouleau, Chantal Ethier, Pierre Gagné, Michael J Hendzel and Guy G Poirier
    Citation: Proteome Science 2010 8:22
    Content type: Research Published on:

  18. Mulberry dwarf (MD), which is caused by phytoplasma, is one of the most serious infectious diseases of mulberry. Phytoplasmas have been associated with diseases in several hundred plant species. The inability ...

    Authors: Xianling Ji, Yingping Gai, Baoyun Lu, Chengchao Zheng and Zhimei Mu
    Citation: Proteome Science 2010 8:20
    Content type: Research Published on:

  19. Salinity is one of the most widespread agricultural problems in arid and semi-arid regions that makes fields unproductive, and soil salinization is a serious problem in the entire world. To determine the effec...

    Authors: Hamid Sobhanian, Roya Razavizadeh, Yohei Nanjo, Ali Akbar Ehsanpour, Ferdous Rastgar Jazii, Nasrin Motamed and Setsuko Komatsu
    Citation: Proteome Science 2010 8:19
    Content type: Research Published on:

  20. The human umbilical cord contains mucoid connective tissue and fibroblast-like cells. These cells named Wharton's jelly cells, (WJCs) display properties similar to mesenchymal stem cells therefore representing...

    Authors: Stefania Angelucci, Marco Marchisio, Fabrizio Di Giuseppe, Laura Pierdomenico, Marilisa Sulpizio, Enrica Eleuterio, Paola Lanuti, Giuseppe Sabatino, Sebastiano Miscia and Carmine Di Ilio
    Citation: Proteome Science 2010 8:18
    Content type: Research Published on:

  21. Heat shock proteins (HSPs), including mainly HSP110, HSP90, HSP70, HSP60 and small HSP families, are evolutionary conserved proteins involved in various cellular processes. Abnormal expression of HSPs has been...

    Authors: Guobo Shen, Shufang Liang, Zhizhong Xu, Liangxue Zhou, Shiyin Xiao, Xiangying Xia, Ronghui Li, Ying Liao, Chao You and Yuquan Wei
    Citation: Proteome Science 2010 8:17
    Content type: Research Published on:

  22. Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis. The hypersensitive analytical technique of proteomics can detect molecular changes before the tumor is palpable. The ...

    Authors: Ming Liu, Chun-Feng Li, Hong-Sheng Chen, Luo-Qiang Lin, Chun-Peng Zhang, Jin-Lu Zhao, Yan Liu, Shu-Jun Zhang, Jun-Chao Jin, Lei Wang and Jia-Ren Liu
    Citation: Proteome Science 2010 8:16
    Content type: Research Published on:

  23. The use of chromatography coupled with mass spectrometry (MS) analysis is a powerful approach to identify proteins, owing to its capacity to fractionate molecules according to different chemical features. The ...

    Authors: Silvia Rocchiccioli, Lorenzo Citti, Claudia Boccardi, Nadia Ucciferri, Lorena Tedeschi, Caterina Lande, Maria Giovanna Trivella and Antonella Cecchettini
    Citation: Proteome Science 2010 8:15
    Content type: Research Published on:

  24. The fat components of red meat products have been of interest to researchers due to the health aspects of excess fat consumption by humans. We hypothesized that differences in protein expression have an impact...

    Authors: Yong Mei Zhao, Urmila Basu, Michael V Dodson, John A Basarb and Le Luo Guan
    Citation: Proteome Science 2010 8:14
    Content type: Research Published on:

  25. The UVB component of solar ultraviolet irradiation is one of the major risk factors for the development of skin cancer in humans. UVB exposure elicits an increased generation of reactive oxygen species (ROS), ...

    Authors: Marzia Perluigi, Fabio Di Domenico, Carla Blarzino, Cesira Foppoli, Chiara Cini, Alessandra Giorgi, Caterina Grillo, Federico De Marco, David A Butterfield, Maria E Schininà and Raffaella Coccia
    Citation: Proteome Science 2010 8:13
    Content type: Research Published on:

  26. The human immunodeficiency virus type 1 (HIV-1) pandemic has continued unabated for nearly 30 years. To better understand the influence of virus on host cells, we performed the differential proteome research o...

    Authors: Lijun Zhang, Xiaofang Jia, Xiaojun Zhang, Jianjun Sun, Xia Peng, Tangkai Qi, Fang Ma, Lin Yin, Yamin Yao, Chao Qiu and Hongzhou Lu
    Citation: Proteome Science 2010 8:12
    Content type: Research Published on:

  27. Our earlier studies have shown that red blood cell (RBC) morphology in Alzheimer's disease (AD) subjects was altered (> 15% of the RBCs were elongated as compared to 5.9% in normal controls (p < 0.0001)). Thes...

    Authors: Joy G Mohanty, Hem D Shukla, Jefferey D Williamson, Lenore J Launer, Satya Saxena and Joseph M Rifkind
    Citation: Proteome Science 2010 8:11
    Content type: Research Published on:

  28. Proteomics is increasingly becoming an important tool for the study of many different aspects of plant functions, such as investigating the molecular processes underlying in plant physiology, development, diff...

    Authors: Kaimian Li, Wenli Zhu, Kang Zeng, Zhenwen Zhang, Jianqiu Ye, Wenjun Ou, Samrina Rehman, Bruria Heuer and Songbi Chen
    Citation: Proteome Science 2010 8:10
    Content type: Research Published on:

  29. In-depth proteomics analyses of tumors are frequently biased by the presence of blood components and stromal contamination, which leads to large experimental variation and decreases the proteome coverage. We h...

    Authors: Luigi De Petris, Maria Pernemalm, Göran Elmberger, Per Bergman, Lotta Orre, Rolf Lewensohn and Janne Lehtiö
    Citation: Proteome Science 2010 8:9
    Content type: Methodology Published on:

  30. Yeast two-hybrid (Y2H) screens have been among the most powerful methods to detect and analyze protein-protein interactions. However, they suffer from a significant degree of false negatives, i.e. true interac...

    Authors: Thorsten Stellberger, Roman Häuser, Armin Baiker, Venkata R Pothineni, Jürgen Haas and Peter Uetz
    Citation: Proteome Science 2010 8:8
    Content type: Research Published on:

  31. The yeast-like epiphytic fungus Pseudozyma flocculosa is known to antagonize powdery mildew fungi through proliferation on colonies presumably preceded by the release of an antifungal glycolipid (flocculosin). In...

    Authors: Walid Hammami, Florian Chain, Dominique Michaud and Richard R Bélanger
    Citation: Proteome Science 2010 8:7
    Content type: Research Published on:

  32. Sea urchin is a major model organism for developmental biology and biomineralization research. However, identification of proteins involved in larval skeleton formation and mineralization processes in the embr...

    Authors: Karlheinz Mann, Albert J Poustka and Matthias Mann
    Citation: Proteome Science 2010 8:6
    Content type: Research Published on:

  33. Hepatitis C virus (HCV) poses a growing threat to global health as it often leads to serious liver diseases and is one of the primary causes for liver transplantation. Currently, no vaccines are available to p...

    Authors: Ragunath Singaravelu, David R Blais, Craig S McKay and John Paul Pezacki
    Citation: Proteome Science 2010 8:5
    Content type: Research Published on:

  34. As part of a clinical proteomics program focused on diabetes and its complications we are looking for new and better protein biomarkers for diabetic nephropathy. The search for new and better biomarkers for di...

    Authors: Anne Julie Overgaard, Henning Gram Hansen, Maria Lajer, Lykke Pedersen, Lise Tarnow, Peter Rossing, James N McGuire and Flemming Pociot
    Citation: Proteome Science 2010 8:4
    Content type: Research Published on:

  35. Although mechanical ventilation (MV) is a major supportive therapy for patients with acute respiratory distress syndrome, it may result in side effects including lung injury. In this study we hypothesize that ...

    Authors: Adrian Doroszko, Thomas S Hurst, Dorota Polewicz, Jolanta Sawicka, Justyna Fert-Bober, David H Johnson and Grzegorz Sawicki
    Citation: Proteome Science 2010 8:3
    Content type: Research Published on:

  36. Pituitary adenomas, the third most common intracranial tumor, comprise nearly 16.7% of intracranial neoplasm and 25%-44% of pituitary adenomas are prolactinomas. Prolactinoma represents a complex heterogeneous...

    Authors: Yingchao Liu, Jinsong Wu, Guoquan Yan, Ruiping Hou, Dongxiao Zhuang, Luping Chen, Qi Pang and Jianhong Zhu
    Citation: Proteome Science 2010 8:2
    Content type: Research Published on:

  37. Insects have an efficient self-defense system that is based on innate immunity. Recent findings have disclosed many parallels between human and insect innate immunity, and simultaneously fine differences in th...

    Authors: Alice Masova, Miloslav Sanda, Jiri Jiracek and Irena Selicharova
    Citation: Proteome Science 2010 8:1
    Content type: Research Published on:

  38. Although 70% (or 2/3) partial hepatectomy (PH) is the most studied model for liver regeneration, the hepatic protein expression profile associated with lower volume liver resection (such as 50% PH) has not yet...

    Authors: Hongcui Cao, Jiong Yu, Wei Xu, Xiaofei Jia, Jinfeng Yang, Qiaoling Pan, Qiyi Zhang, Guoping Sheng, Jun Li, Xiaoping Pan, Yingjie Wang and Lanjuan Li
    Citation: Proteome Science 2009 7:48
    Content type: Research Published on:

  39. Plant Growth Promoting Rhizobacteria (PGPR), Pseudomonas fluorescens strain KH-1 was found to exhibit plant growth promotional activity in rice under both in-vitro and in-vivo conditions. But the mechanism underl...

    Authors: Saveetha Kandasamy, Karthiba Loganathan, Raveendran Muthuraj, Saravanakumar Duraisamy, Suresh Seetharaman, Raguchander Thiruvengadam, Balasubramanian Ponnusamy and Samiyappan Ramasamy
    Citation: Proteome Science 2009 7:47
    Content type: Research Published on:

  40. Progression through the cell cycle is accompanied by tightly controlled regulation of transcription. On one hand, a subset of genes is expressed in a cell cycle-dependent manner. On the other hand, a general i...

    Authors: WWM Pim Pijnappel, Annemieke Kolkman, Marijke PA Baltissen, Albert JR Heck and HT Marc Timmers
    Citation: Proteome Science 2009 7:46
    Content type: Research Published on:

  41. Mycoplasma hyopneumoniae is a highly infectious swine pathogen and is the causative agent of enzootic pneumonia (EP). Following the previous report of a proteomic survey of the pathogenic 7448 strain of swine pa...

    Authors: Paulo M Pinto, Cátia S Klein, Arnaldo Zaha and Henrique B Ferreira
    Citation: Proteome Science 2009 7:45
    Content type: Research Published on:

  42. While the larval-juvenile transition (metamorphosis) in the spionid polychaete Pseudopolydora vexillosa involves gradual morphological changes and does not require substantial development of juvenile organs, the ...

    Authors: Flora SY Mok, Vengatesen Thiyagarajan and Pei-Yuan Qian
    Citation: Proteome Science 2009 7:44
    Content type: Research Published on:

  43. B-cell lymphomas are thought to reflect different stages of B-cell maturation. Based on cytogenetics and molecular markers, mantle cell lymphoma (MCL) is presumed to derive predominantly from naïve, pre-germin...

    Authors: Henrik Stranneheim, Lukas M Orre, Janne Lehtiö and Jenny Flygare
    Citation: Proteome Science 2009 7:43
    Content type: Research Published on:

  44. Under conditions of salt stress, plants respond by initiating phosphorylation cascades. Many key phosphorylation events occur at the membrane. However, to date only limited sites have been identified that are ...

    Authors: Jue-Liang Hsu, Lan-Yu Wang, Shu-Ying Wang, Ching-Huang Lin, Kuo-Chieh Ho, Fong-Ku Shi and Ing-Feng Chang
    Citation: Proteome Science 2009 7:42
    Content type: Research Published on:

  45. Dorsal root ganglion (DRG) neurons are primary sensory neurons that conduct neuronal impulses related to pain, touch and temperature senses. Plasma membrane (PM) of DRG cells plays important roles in their fun...

    Authors: Xia Xiong, Sha Huang, Hai Zhang, Jianjun Li, Jianying Shen, Jixian Xiong, Yong Lin, Liping Jiang, Xianchun Wang and Sonping Liang
    Citation: Proteome Science 2009 7:41
    Content type: Research Published on:

  46. The broad range in growth observed in response to growth hormone (GH) treatment is mainly caused by individual variations in both GH secretion and GH sensitivity. Individual GH responsiveness can be estimated ...

    Authors: Björn Andersson, Gunnel Hellgren, Andreas FM Nierop, Ze'ev Hochberg and Kerstin Albertsson-Wikland
    Citation: Proteome Science 2009 7:40
    Content type: Research Published on:

  47. Hepatitis E, caused by the hepatitis E virus (HEV), is endemic to developing countries where it manifests as waterborne outbreaks and sporadic cases. Though generally self-limited with a low mortality rate, so...

    Authors: Shikha Taneja, Somdutta Sen, Vijay K Gupta, Rakesh Aggarwal and Shahid Jameel
    Citation: Proteome Science 2009 7:39
    Content type: Research Published on:

  48. Two-dimensional gel electrophoresis (2-DE) is a powerful method to study protein expression and function in living organisms and diseases. This technique, however, has not been applied to avian bursa of Fabric...

    Authors: Yongping Wu, Jiyong Zhou, Xin Zhang, Xiaojuan Zheng, Xuetao Jiang, Lixue Shi, Wei Yin and Junhua Wang
    Citation: Proteome Science 2009 7:38
    Content type: Methodology Published on:

  49. Acinetobacter baumannii is a nosocomial pathogen that has been associated with outbreak infections in hospitals. Despite increasing awareness about this bacterium, its proteome remains poorly characterised, howe...

    Authors: Nelson C Soares, Maria P Cabral, José R Parreira, Carmen Gayoso, Maria J Barba and Germán Bou
    Citation: Proteome Science 2009 7:37
    Content type: Research Published on:
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