Research
Epidermal growth factor receptor (EGFR) mutation-induced drug resistance is a difficult problem in lung cancer treatment. Studying the molecular mechanisms of drug resistance can help to develop corresponding ...
Proteome Science 2016 14:12
Published on: 8 September 2016
Research
Metal-organic frameworks (MOFs - MIL-101) are the most exciting, high profiled developments in nanotechnology in the last ten years, and it attracted considerable attention owing to their uniform nanoporosity,...
Proteome Science 2016 14:11
Published on: 6 September 2016
Research
Cervical cancer (CC) is the fourth most common cancer in women worldwide with an estimated 528,000 new cases in 2012. The same year México had an incidence of 13,960 and a mortality of 4769 cases. There are se...
Proteome Science 2016 14:10
Published on: 5 September 2016
Research
The molecular mechanism underlying broiler fat deposition is still poorly understood.
Proteome Science 2016 14:9
Published on: 1 September 2016
Research
RAW 264.7 cells can differentiate into osteoclasts when cultured in medium supplemented with 1 % FBS. However, the proteomic changes in the development of RAW 264.7 cells into osteoclasts in low serum culture ...
Proteome Science 2016 14:8
Published on: 31 March 2016
Research
Cystatin C (CysC) is an endogenous cysteine protease inhibitor that can be used to assess the progression of kidney function. Recent studies demonstrate that CysC is a more specific indicator of glomerular fil...
Proteome Science 2016 14:7
Published on: 25 March 2016
Research
Maternal Embryonic Leucine Zipper Kinase (MELK) is a serine/threonine kinase involved in cell cycle, differentiation, proliferation, and apoptosis. These multiple features are consistent with it being a potent...
Proteome Science 2016 14:6
Published on: 11 March 2016
Research
The cellular immune response for Mycobacterium tuberculosis (M. tuberculosis) infection remained incompletely understood. To uncover membrane proteins involved in this infection mechanism, an integrated approach ...
Proteome Science 2016 14:5
Published on: 8 March 2016
Methodology
Kidney stone matrix protein composition is an important yet poorly understood aspect of nephrolithiasis. We hypothesized that this proteome is considerably more complex than previous reports have indicated and...
Proteome Science 2016 14:4
Published on: 27 February 2016
Research
Non-alcoholic fatty liver disease (NAFLD) is a clinical frequent disease. However, its pathogenesis still needs further study, especially the mechanism at the molecular level. The recent identified novel prote...
Proteome Science 2016 14:3
Published on: 3 February 2016
Research
Rice bacterial blight (BB) caused by Xanthomonas oryzae pv.oryzae (Xoo) is one of the most devastating bacterial diseases in rice-growing regions worldwide. The rice-Xoo interaction is a classical model for study...
Proteome Science 2016 14:2
Published on: 2 February 2016
Research
Snake venom is a source of many pharmacologically important molecules. Agkistrodon bilineatus commonly known as Cantil, is spread over Central America particularly in Mexico and Costa Rica. From the venom of Agki...
Proteome Science 2016 14:1
Published on: 14 January 2016
Research
The periodontal disease is caused by a set of inflammatory disorders characterized by periodontal pocket formation that lead to tooth loss if untreated. The proteomic profile and related molecular conditions o...
Proteome Science 2015 13:33
Published on: 30 December 2015
Research
Intrauterine growth restriction (IUGR) may program metabolic alterations affecting physiological functions and lead to diseases in later life. The adipose tissue is an important organ influencing energy homeos...
Proteome Science 2015 13:32
Published on: 2 December 2015
Research
Membrane microdomains represent dynamic membrane nano-assemblies enriched in signaling molecules suggesting their active involvement in not only physiological but also pathological molecular processes. The hyp...
Proteome Science 2015 13:30
Published on: 1 December 2015
Research
It has been discussed if the adverse health effect associated with the ingestion of trans fatty acids correlates with the food source, as the composition of the isomers varies in different foods. We have investig...
Proteome Science 2015 13:31
Published on: 1 December 2015
Research
The proteins of avian eggshell organic matrices are thought to control the mineralization of the eggshell in the shell gland (uterus). Proteomic analysis of such matrices identified many candidates for such a ...
Proteome Science 2015 13:29
Published on: 1 December 2015
Research
The oil palm Elaeis guineensis Jacq. which produces the highest yield per unit land area of the oil crops is the most important commercial oil crop in South East Asia. The fleshy mesocarp of oil palm fruit, where...
Proteome Science 2015 13:28
Published on: 26 November 2015
Research
At low temperatures, rice grains have a reduced germination rate and grow more slowly, which delays the emergence of rice seedlings from the paddy water surface and significantly increases seedling mortality. ...
Proteome Science 2015 13:27
Published on: 18 November 2015
Research
The harmful consequences of in utero irradiation on learning and memory have been recognised but the molecular mechanisms behind the damage are still unknown.
Proteome Science 2015 13:26
Published on: 16 November 2015
Research
Bats are recognised as an important reservoir for a number of highly pathogenic zoonotic viruses. While many of these viruses cause severe and often fatal disease in humans, bats are able to coexist with these...
Proteome Science 2015 13:25
Published on: 2 November 2015
Research
Histones and their post-translational modifications impact cellular function by acting as key regulators in the maintenance and remodeling of chromatin, thus affecting transcription regulation either positivel...
Proteome Science 2015 13:24
Published on: 24 September 2015
Methodology
Protein immunoprecipitation (IP) coupled with MS provides means to interrogate protein complexes and their posttranslational modifications (PTMs). In a typical protein IP assay antibodies are conjugated to pro...
Proteome Science 2015 13:23
Published on: 2 September 2015
Research article
Eggshell mineralization in commercially important species such as chicken, turkey or quail is of interest as a general model of calcium carbonate biomineralization. Knowledge of proteins and molecular mechanis...
Proteome Science 2015 13:22
Published on: 27 August 2015
Research article
The calcitic brachipod shells contain proteins that play pivotal roles in shell formation and are important in understanding the evolution of biomineralization. Here, we performed a large-scale exploration of ...
Proteome Science 2015 13:21
Published on: 15 August 2015
Proteome Science is affiliated with the Korean Human Proteome Organization (KHUPO). KHUPO is a global leader in both domestic and global proteomics research, establishing an industry-academia-government joint cooperation system to effectively carry out global proteome projects and research such as the human genome project
