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Volume 11 Supplement 1

Selected articles from the IEEE International Conference on Bioinformatics and Biomedicine 2012: Proteome Science


Edited by Fang-Xiang Wu, Jianxin Wang and Xiaohua Hu

Publication of this supplement has not been supported by sponsorship. Information about the source of funding for the publication charges can be found in the individual articles. Articles have undergone the journal's standard peer review process for supplements. The Supplement Editors declare that they have no competing interests.

IEEE International Conference on Bioinformatics and Biomedicine 2012. Go to conference site.

Philadelphia, PA, USA4-7 October 2012

  1. Today large scale genome sequencing technologies are uncovering an increasing amount of new genes and proteins, which remain uncharacterized. Experimental procedures for protein function prediction are low thr...

    Authors: Alfredo Benso, Stefano Di Carlo, Hafeez ur Rehman, Gianfranco Politano, Alessandro Savino and Prashanth Suravajhala
    Citation: Proteome Science 2013 11(Suppl 1):S1
  2. Protein-protein interactions (PPIs) play a key role in understanding the mechanisms of cellular processes. The availability of interactome data has catalyzed the development of computational approaches to eluc...

    Authors: Young-Rae Cho, Marco Mina, Yanxin Lu, Nayoung Kwon and Pietro H Guzzi
    Citation: Proteome Science 2013 11(Suppl 1):S3
  3. β-turns are secondary structure type that have essential role in molecular recognition, protein folding, and stability. They are found to be the most common type of non-repetitive structures since 25% of amino ....

    Authors: Murtada Khalafallah Elbashir, Jianxin Wang, Fang-Xiang Wu and Lusheng Wang
    Citation: Proteome Science 2013 11(Suppl 1):S5
  4. Membrane proteins perform essential roles in diverse cellular functions and are regarded as major pharmaceutical targets. The significance of membrane proteins has led to the developing dozens of resources rel...

    Authors: Min-Sung Kim and Gwan-Su Yi
    Citation: Proteome Science 2013 11(Suppl 1):S7
  5. To understand the function of protein complexes and their association with biological processes, a lot of studies have been done towards analyzing the protein-protein interaction (PPI) networks. However, the a...

    Authors: Chengwei Lei, Saleh Tamim, Alexander JR Bishop and Jianhua Ruan
    Citation: Proteome Science 2013 11(Suppl 1):S9
  6. The sequence database searching has been the dominant method for peptide identification, in which a large number of peptide spectra generated from LC/MS/MS experiments are searched using a search engine agains...

    Authors: Xijun Liang, Zhonghang Xia, Xinnan Niu, Andrew J Link, Liping Pang, Fang-Xiang Wu and Hongwei Zhang
    Citation: Proteome Science 2013 11(Suppl 1):S10
  7. Differences in sample collection, biomolecule extraction, and instrument variability introduce bias to data generated by liquid chromatography coupled with mass spectrometry (LC-MS). Normalization is used to a...

    Authors: Mohammad R Nezami Ranjbar, Yi Zhao, Mahlet G Tadesse, Yue Wang and Habtom W Ressom
    Citation: Proteome Science 2013 11(Suppl 1):S13
  8. Phosphorylation site assignment of high throughput tandem mass spectrometry (LC-MS/MS) data is one of the most common and critical aspects of phosphoproteomics. Correctly assigning phosphorylated residues help...

    Authors: Fahad Saeed, Trairak Pisitkun, Jason D Hoffert, Sara Rashidian, Guanghui Wang, Marjan Gucek and Mark A Knepper
    Citation: Proteome Science 2013 11(Suppl 1):S14
  9. The immune system must detect a wide variety of microbial pathogens, such as viruses, bacteria, fungi and parasitic worms, to protect the host against disease. Antigenic peptides displayed by MHC II (class II ...

    Authors: Wen-Jun Shen, Shaohong Zhang and Hau-San Wong
    Citation: Proteome Science 2013 11(Suppl 1):S15
  10. Tandem affinity purification coupled with mass-spectrometry (TAP/MS) analysis is a popular method for the identification of novel endogenous protein-protein interactions (PPIs) in large-scale. Computational an...

    Authors: Xiaoyun Sun, Pengyu Hong, Meghana Kulkarni, Young Kwon and Norbert Perrimon
    Citation: Proteome Science 2013 11(Suppl 1):S16
  11. Biomedical extraction based on supervised machine learning still faces the problem that a limited labeled dataset does not saturate the learning method. Many supervised learning algorithms for bio-event extrac...

    Authors: Jian Wang, Qian Xu, Hongfei Lin, Zhihao Yang and Yanpeng Li
    Citation: Proteome Science 2013 11(Suppl 1):S17
  12. Proteins are essential biological molecules which play vital roles in nearly all biological processes. It is the tertiary structure of a protein that determines its functions. Therefore the prediction of a pro...

    Authors: Jyh-Jong Tsay and Shih-Chieh Su
    Citation: Proteome Science 2013 11(Suppl 1):S19
  13. Protein interaction networks (PINs) are known to be useful to detect protein complexes. However, most available PINs are static, which cannot reflect the dynamic changes in real networks. At present, some rese...

    Authors: Qianghua Xiao, Jianxin Wang, Xiaoqing Peng and Fang-Xiang Wu
    Citation: Proteome Science 2013 11(Suppl 1):S20
  14. Many computational approaches have been developed to detect protein complexes from protein-protein interaction (PPI) networks. However, these PPI networks are always built from high-throughput experiments. The...

    Authors: Bo Xu, Hongfei Lin, Kavishwar B Wagholikar, Zhihao Yang and Hongfang Liu
    Citation: Proteome Science 2013 11(Suppl 1):S21

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