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  1. Maternal Embryonic Leucine Zipper Kinase (MELK) is a serine/threonine kinase involved in cell cycle, differentiation, proliferation, and apoptosis. These multiple features are consistent with it being a potent...

    Authors: Suely Kazue Nagahashi Marie, Sueli Mieko Oba-Shinjo, Roseli da Silva, Marcela Gimenez, Gisele Nunes Reis, Jean-Pierre Tassan, Jose Cesar Rosa and Miyuki Uno
    Citation: Proteome Science 2016 14:6
    Content type: Research Published on:

  2. The cellular immune response for Mycobacterium tuberculosis (M. tuberculosis) infection remained incompletely understood. To uncover membrane proteins involved in this infection mechanism, an integrated approach ...

    Authors: Chiu-Ping Kuo, Kuo-Song Chang, Jue-Liang Hsu, I-Fang Tsai, Andrew Boyd Lin, Tsai-Yin Wei, Chien-Liang Wu and Yen-Ta Lu
    Citation: Proteome Science 2016 14:5
    Content type: Research Published on:

  3. Kidney stone matrix protein composition is an important yet poorly understood aspect of nephrolithiasis. We hypothesized that this proteome is considerably more complex than previous reports have indicated and...

    Authors: Frank A. Witzmann, Andrew P. Evan, Fredric L. Coe, Elaine M. Worcester, James E. Lingeman and James C. Williams Jr
    Citation: Proteome Science 2016 14:4
    Content type: Methodology Published on:

  5. Rice bacterial blight (BB) caused by Xanthomonas oryzae pv.oryzae (Xoo) is one of the most devastating bacterial diseases in rice-growing regions worldwide. The rice-Xoo interaction is a classical model for study...

    Authors: Xian Chen, Zhiping Deng, Chulang Yu, Chengqi Yan and Jianping Chen
    Citation: Proteome Science 2016 14:2
    Content type: Research Published on:

  6. Snake venom is a source of many pharmacologically important molecules. Agkistrodon bilineatus commonly known as Cantil, is spread over Central America particularly in Mexico and Costa Rica. From the venom of Agki...

    Authors: Aisha Munawar, Anum Zahid, Amr Negm, Ahmed Akrem, Patrick Spencer and Christian Betzel
    Citation: Proteome Science 2016 14:1
    Content type: Research Published on:

  7. The periodontal disease is caused by a set of inflammatory disorders characterized by periodontal pocket formation that lead to tooth loss if untreated. The proteomic profile and related molecular conditions o...

    Authors: Emanuela Monari, Aurora Cuoghi, Elisa Bellei, Stefania Bergamini, Andrea Lucchi, Aldo Tomasi, Pierpaolo Cortellini, Davide Zaffe and Carlo Bertoldi
    Citation: Proteome Science 2015 13:33
    Content type: Research Published on:

  8. Intrauterine growth restriction (IUGR) may program metabolic alterations affecting physiological functions and lead to diseases in later life. The adipose tissue is an important organ influencing energy homeos...

    Authors: Adriana Pereira de Souza, Amanda Paula Pedroso, Regina Lúcia Harumi Watanabe, Ana Paula Segantine Dornellas, Valter Tadeu Boldarine, Helen Julie Laure, Claudia Maria Oller do Nascimento, Lila Missae Oyama, José Cesar Rosa and Eliane Beraldi Ribeiro
    Citation: Proteome Science 2015 13:32
    Content type: Research Published on:

  9. It has been discussed if the adverse health effect associated with the ingestion of trans fatty acids correlates with the food source, as the composition of the isomers varies in different foods. We have investig...

    Authors: Toke P. Krogager, Lone Vendel Nielsen, Derya Kahveci, Thomas F. Dyrlund, Carsten Scavenius, Kristian W. Sanggaard and Jan J. Enghild
    Citation: Proteome Science 2015 13:31
    Content type: Research Published on:

  10. Membrane microdomains represent dynamic membrane nano-assemblies enriched in signaling molecules suggesting their active involvement in not only physiological but also pathological molecular processes. The hyp...

    Authors: Viorel-Iulian Suica, Elena Uyy, Raluca Maria Boteanu, Luminita Ivan and Felicia Antohe
    Citation: Proteome Science 2015 13:30
    Content type: Research Published on:

  12. The oil palm Elaeis guineensis Jacq. which produces the highest yield per unit land area of the oil crops is the most important commercial oil crop in South East Asia. The fleshy mesocarp of oil palm fruit, where...

    Authors: Tony Eng Keong Ooi, Wan Chin Yeap, Leona Daniela Jeffery Daim, Boon Zean Ng, Fong Chin Lee, Ainul Masni Othman, David Ross Appleton, Fook Tim Chew and Harikrishna Kulaveerasingam
    Citation: Proteome Science 2015 13:28
    Content type: Research Published on:

  14. The harmful consequences of in utero irradiation on learning and memory have been recognised but the molecular mechanisms behind the damage are still unknown.

    Authors: Stefan J. Kempf, Christine von Toerne, Stefanie M. Hauck, Michael J. Atkinson, Mohammed A. Benotmane and Soile Tapio
    Citation: Proteome Science 2015 13:26
    Content type: Research Published on:

  15. Bats are recognised as an important reservoir for a number of highly pathogenic zoonotic viruses. While many of these viruses cause severe and often fatal disease in humans, bats are able to coexist with these...

    Authors: Lawrence Mok, James W. Wynne, Kris Ford, Brian Shiell, Antony Bacic and Wojtek P. Michalski
    Citation: Proteome Science 2015 13:25
    Content type: Research Published on:

  16. Histones and their post-translational modifications impact cellular function by acting as key regulators in the maintenance and remodeling of chromatin, thus affecting transcription regulation either positivel...

    Authors: Pawel Olszowy, Maire Rose Donnelly, Chanho Lee and Pawel Ciborowski
    Citation: Proteome Science 2015 13:24
    Content type: Research Published on:

  17. Protein immunoprecipitation (IP) coupled with MS provides means to interrogate protein complexes and their posttranslational modifications (PTMs). In a typical protein IP assay antibodies are conjugated to pro...

    Authors: Michal Mikula, Tymon Rubel, Jakub Karczmarski, Malgorzata Statkiewicz, Karol Bomsztyk and Jerzy Ostrowski
    Citation: Proteome Science 2015 13:23
    Content type: Methodology Published on:

  19. The calcitic brachipod shells contain proteins that play pivotal roles in shell formation and are important in understanding the evolution of biomineralization. Here, we performed a large-scale exploration of ...

    Authors: Yukinobu Isowa, Isao Sarashina, Kenshiro Oshima, Keiji Kito, Masahira Hattori and Kazuyoshi Endo
    Citation: Proteome Science 2015 13:21
    Content type: Research article Published on:

  20. The mouse epididymis performs an essential role in sperm maturation, but global protein expression data in mouse epididymis are still lacking. Here, we reported the first in-depth gel-based profiling of mouse ...

    Authors: Xin Liu, Fu-Jun Liu, Shao-Hua Jin, Xiao-Fang Shen and Yan-Wei Wang
    Citation: Proteome Science 2015 13:20
    Content type: Research article Published on:

  22. Differentiated cell nuclei can be reprogrammed to a pluripotent state in several ways, including incubation with oocyte extracts, transfer into enucleated oocytes, and induced pluripotent stem cell technology....

    Authors: Qi Zhao, Zheng Guo, Shanhua Piao, Chunsheng Wang and Tiezhu An
    Citation: Proteome Science 2015 13:18
    Content type: Research Published on:

  23. Vitellogenin (Vtg) is the major egg yolk protein (YP) in most oviparous species and may be useful as an indicator in ecotoxicological testing at the biochemical level. In this study, we obtained detailed infor...

    Authors: Natalia A Petushkova, Galina P Kuznetsova, Olesya V Larina, Yulia S Kisrieva, Natalia F Samenkova, Oxana P Trifonova, Yuliana V Miroshnichenko, Konstantin V Zolotarev, Irina I Karuzina, Olga M Ipatova and Andrey V Lisitsa
    Citation: Proteome Science 2015 13:17
    Content type: Research article Published on:

  24. Cultivation of osteoclasts is a basic tool for investigating osteolytic bone diseases. Fetal bovine serum (FBS) is the standard supplement used for in vitro cell culture medium. Typically, the serum volume fracti...

    Authors: Qi Xiong, Lihai Zhang, Lingli Xin, Yanpan Gao, Ye Peng, Peifu Tang and Wei Ge
    Citation: Proteome Science 2015 13:16
    Content type: Research article Published on:

  25. As the rapid growth of the commercialized acreage in genetically modified (GM) crops, the unintended effects of GM crops’ biosafety assessment have been given much attention. To investigate whether transgenic ...

    Authors: Limin Wang, Xuchu Wang, Xiang Jin, Ruizong Jia, Qixing Huang, Yanhua Tan and Anping Guo
    Citation: Proteome Science 2015 13:15
    Content type: Research article Published on:

  26. Transgelin2, one of cytoskeletal actin binding proteins has recently been suggested to be involved in the formation of immune synapses. Although detailed function of transgelin2 is largely unknown, interaction...

    Authors: Se Hwan Jang, Chang-Duk Jun and Zee-Yong Park
    Citation: Proteome Science 2015 13:14
    Content type: Research Published on:

  27. Using auditory discrimination learning in gerbils, we have previously shown that activation of auditory-cortical D1/D5 dopamine receptors facilitates mTOR-mediated, protein synthesis-dependent mechanisms of me...

    Authors: Nicole Reichenbach, Ulrike Herrmann, Thilo Kähne, Horst Schicknick, Rainer Pielot, Michael Naumann, Daniela C Dieterich, Eckart D Gundelfinger, Karl-Heinz Smalla and Wolfgang Tischmeyer
    Citation: Proteome Science 2015 13:13
    Content type: Research article Published on:

  28. Pseudoprogression disease (PsPD) is commonly observed during glioblastoma (GBM) follow-up after adjuvant therapy. Because it is difficult to differentiate PsPD from true early progression of GBM, we have used ...

    Authors: Peng Zhang, Zhengguang Guo, Yang Zhang, Zhixian Gao, Nan Ji, Danqi Wang, Lili Zou, Wei Sun and Liwei Zhang
    Citation: Proteome Science 2015 13:12
    Content type: Research article Published on:

  29. Neks are serine-threonine kinases that are similar to NIMA, a protein found in Aspergillus nidulans which is essential for cell division. In humans there are eleven Neks which are involved in different biological...

    Authors: Fernanda Luisa Basei, Gabriela Vaz Meirelles, Germanna Lima Righetto, Deivid Lucas dos Santos Migueleti, Juliana Helena Costa Smetana and Jörg Kobarg
    Citation: Proteome Science 2015 13:11
    Content type: Research article Published on:

  30. Knowledge of the mouse salivary proteome is not well documented and as a result, very limited. Currently, several salivary proteins remain unidentified and for some others, their function yet to be determined....

    Authors: Anne A Blanchard, Peyman Ezzati, Dmitry Shamshurin, Andreea C Nistor, Etienne Leygue, John A Wilkins and Yvonne Myal
    Citation: Proteome Science 2015 13:10
    Content type: Research article Published on:

  31. Ammonia is a well-known toxicant both existing in atmospheric and aquatic system. So far, most studies of ammonia toxicity focused on mammals or aquatic animals. With the development of poultry industry, ammon...

    Authors: Jize Zhang, Cong Li, Xiangfang Tang, Qingping Lu, Renna Sa and Hongfu Zhang
    Citation: Proteome Science 2015 13:9
    Content type: Research article Published on:

  32. In this study, we searched for proteins that change their expression in the olfactory bulb (oB) of rats during ontogenesis. Up to now, protein expression differences in the developing animal are not fully unde...

    Authors: Michael Wille, Antje Schümann, Michael Kreutzer, Michael O Glocker, Andreas Wree, Grit Mutzbauer and Oliver Schmitt
    Citation: Proteome Science 2015 13:8
    Content type: Research article Published on:

  33. While formation of mineralized tissue is characteristic of many animal taxa, the proteins that interact with mineral are diverse and appear in many cases to be of independent origin. Extracellular matrix prote...

    Authors: Ryan W Seaver and Brian T Livingston
    Citation: Proteome Science 2015 13:7
    Content type: Research article Published on:

  34. Adrenal glands are essential endocrine organs composed of two embryological distinct tissues. Morphological changes during their development are well described, but less understood with regard to their molecul...

    Authors: Gry H Dihazi, Gerhard A Mueller, Abdul R Asif, Marwa Eltoweissy, Johannes T Wessels and Hassan Dihazi
    Citation: Proteome Science 2015 13:6
    Content type: Research article Published on:

    The Correction to this article has been published in Proteome Science 2018 16:10

  35. Finding the best extraction method of proteins from lysed cells is the key step for detection and identification in all proteomics applications. These are important to complement the knowledge about the mechan...

    Authors: Carolina B Malafaia, Myrzânia L Guerra, Túlio D Silva, Patrícia MG Paiva, Elineide B Souza, Maria TS Correia and Márcia V Silva
    Citation: Proteome Science 2015 13:5
    Content type: Methodology Published on:

  36. Peroxiredoxin V (Prdx V) plays a major role in preventing oxidative damage as an effective antioxidant protein within a variety of cells through peroxidase activity. However, the function of Prdx V is not limi...

    Authors: Sun Hee Ahn, Hee-Young Yang, Gia Buu Tran, Joseph Kwon, Kyu-Yeol Son, Suhee Kim, Quoc Thuong Dinh, Seunggon Jung, Ha-Mi Lee, Kyoung-Oh Cho and Tae-Hoon Lee
    Citation: Proteome Science 2015 13:4
    Content type: Research article Published on:

  37. Pyrenophora tritici-repentis is a phytopathogenic fungus which causes tan spot on wheat. Some races of P. tritici-repentis produce host-specific toxins which present symptoms of chlorosis or ne...

    Authors: Jacqueline Day, Roman Daniel Gietz and Christof Rampitsch
    Citation: Proteome Science 2015 13:3
    Content type: Research article Published on:

  38. Despite the overall success of prostate specific antigen (PSA) in screening and detection of prostate cancer (PCa), its use has been limited due to the lack of specificity. The principal driving goal currently...

    Authors: Katarina Davalieva, Sanja Kiprijanovska, Selim Komina, Gordana Petrusevska, Natasha Chokrevska Zografska and Momir Polenakovic
    Citation: Proteome Science 2015 13:2
    Content type: Research article Published on:

  39. Chemoresistance remains a significant challenge in chronic myelogenous leukemia (CML) management, which is one of the most critical prognostic factors. Elucidation the molecular mechanisms underlying the resis...

    Authors: Shi Qinghong, Gao Shen, Song Lina, Zhao Yueming, Li Xiaoou, Wu Jianlin, He Chengyan, Li Hongjun and Zhao Haifeng
    Citation: Proteome Science 2015 13:1
    Content type: Research article Published on:

  40. We investigated the effects of mycophenolate mofetil (MMF) on kidney function and on protein phosphorylation in a mouse model for the human Alport syndrome.

    Authors: Darinka Todorova Petrova, Frank Christian Schultze, Gunnar Brandhorst, Klaus-Dieter Luchs, Christof Lenz, Henning Urlaub, Diana Rubel, Oliver Gross, Philip D Walson and Michael Oellerich
    Citation: Proteome Science 2014 12:56
    Content type: Research article Published on:

  41. The total protein contents of rice seeds are significantly higher in the three wild rice species (Oryza rufipogon Grill., Oryza officinalis Wall. and Oryza meyeriana Baill.) than in the cultivated rice (Oryza sat...

    Authors: Chunmiao Jiang, Zaiquan Cheng, Cheng Zhang, Tengqiong Yu, Qiaofang Zhong, J Qingxi Shen and Xingqi Huang
    Citation: Proteome Science 2014 12:51
    Content type: Research article Published on:

  42. Osteoarthritis (OA) is a chronic degenerative disease of the articular cartilage, and its diagnosis is based on symptoms and radiological signs that are only present in the late stages of the disease. Due to t...

    Authors: Nancy Marbella Parra-Torres, Febe Elena Cázares-Raga and Juan Bautista Kouri
    Citation: Proteome Science 2014 12:55
    Content type: Research article Published on:

  43. Mass spectrometry-based proteomics experiments generate spectra that are rich in information. Often only a fraction of this information is used for peptide/protein identification, whereas a significant proport...

    Authors: Trung Nghia Vu, Aida Mrzic, Dirk Valkenborg, Evelyne Maes, Filip Lemière, Bart Goethals and Kris Laukens
    Citation: Proteome Science 2014 12:54
    Content type: Methodology Published on:

  44. Transcription factors bind to response elements on the promoter regions of genes to regulate transcriptional activity. One of the major problems with identifying transcription factors is their low abundance re...

    Authors: Linda I Nagore, YanWen Zhou, Robert J Nadeau, YinShan Jia and Harry W Jarrett
    Citation: Proteome Science 2014 12:53
    Content type: Research article Published on:

  45. Pancreatic cancer development is associated with characteristic alterations like desmoplastic reaction and immune escape which are mediated by the cell-cell communication mechanism and by the microenvironment ...

    Authors: Susanne Klein-Scory, Mahnaz Moradian Tehrani, Christina Eilert-Micus, Kamila A Adamczyk, Nathalie Wojtalewicz, Martina Schnölzer, Stephan A Hahn, Wolff Schmiegel and Irmgard Schwarte-Waldhoff
    Citation: Proteome Science 2014 12:50
    Content type: Research article Published on:

  46. The cytokine MIF (Macrophage Migration Inhibitory Factor) has diverse physiological roles and is present at elevated concentrations in numerous disease states. However, its molecular heterogeneity has not been...

    Authors: Nisha D Sherma, Chad R Borges, Olgica Trenchevska, Jason W Jarvis, Douglas S Rehder, Paul E Oran, Randall W Nelson and Dobrin Nedelkov
    Citation: Proteome Science 2014 12:52
    Content type: Research article Published on:

  47. Acute coronary syndrome is the major cause of death in developed countries. Despite its high prevalence, there is still a strong need for new biomarkers which permit faster and more accurate diagnostics and ne...

    Authors: Carlos M Laborde, Sergio Alonso-Orgaz, Laura Mourino-Alvarez, José Moreu, Fernando Vivanco, Luis R Padial and María G Barderas
    Citation: Proteome Science 2014 12:43
    Content type: Research Published on:

  48. The rapid progress of proteomics over the past years has allowed the discovery of a large number of potential biomarker candidates to improve early tumor diagnosis and therapeutic response, thus being further ...

    Authors: Ionela Daniela Popescu, Elena Codrici, Lucian Albulescu, Simona Mihai, Ana-Maria Enciu, Radu Albulescu and Cristiana Pistol Tanase
    Citation: Proteome Science 2014 12:47
    Content type: Research article Published on:

  49. The zootechnical performance of three different commercial feeds and their impact on liver and serum proteins of gilthead sea bream (Sparus aurata, L.) were assessed in a 12 week feeding trial. The three feeds, n...

    Authors: Stefania Ghisaura, Roberto Anedda, Daniela Pagnozzi, Grazia Biosa, Simona Spada, Elia Bonaglini, Roberto Cappuccinelli, Tonina Roggio, Sergio Uzzau and Maria Filippa Addis
    Citation: Proteome Science 2014 12:44
    Content type: Research article Published on:

  50. Visceral leishmaniasis (VL) is a deadly parasitic diseases caused by Leishmania donovani; it is a major health problem in many countries. A lack of proper understanding of the disease biology, poor diagnostic met...

    Authors: Arup Kumar Bag, Sutapa Saha, Shyam Sundar, Bibhuti Saha, Abhijit Chakrabarti and Chitra Mandal
    Citation: Proteome Science 2014 12:48
    Content type: Research article Published on:
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