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  1. Polypterus senegalus can fully regenerate its pectoral lobed fins, including a complex endoskeleton, with remarkable precision. However, despite the enormous potential of this species for use in medical research,...

    Authors: Suxiang Lu, Qian Xiong, Kang Du, Xiaoni Gan, Xuzhen Wang, Liandong Yang, Ying Wang, Feng Ge and Shunping He

    Citation: Proteome Science 2019 17:6

    Content type: Research

    Published on:

  2. In previous study, we performed next-gene sequencing to investigate the differentially expressed transcripts of bovine follicular granulosa cells (GCs) at dominant follicle (DF) and subordinate follicle (SF) s...

    Authors: Shuning Hou, Qingling Hao, Zhiwei Zhu, Dongmei Xu, Wenzhong Liu, Lihua Lyu and Pengfei Li

    Citation: Proteome Science 2019 17:4

    Content type: Research

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  3. The periodontal ligament is essential for homeostasis of periodontal tissue. A hypoxic milieu of the periodontal tissue is generated under periodontitis or during orthodontic treatment, which affects the perio...

    Authors: Qiwen Li, Tao Luo, Wenxin Lu, Xiaoxiao Yi, Zhihe Zhao and Jun Liu

    Citation: Proteome Science 2019 17:3

    Content type: Research

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  4. The rumen microbiota is one of the most complex consortia of anaerobes, involving archaea, bacteria, protozoa, fungi and phages. They are very effective at utilizing plant polysaccharides, especially cellulose...

    Authors: Hana Sechovcová, Lucie Kulhavá, Kateřina Fliegerová, Mária Trundová, Daniel Morais, Jakub Mrázek and Jan Kopečný

    Citation: Proteome Science 2019 17:2

    Content type: Research

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  5. Non-alcoholic fatty liver disease (NAFLD) is caused by excessive accumulation of fat within the liver, leading to further severe conditions such as non-alcoholic steatohepatitis (NASH). Progression of healthy ...

    Authors: Peerut Chienwichai, Onrapak Reamtong, Usa Boonyuen, Trairak Pisitkun, Poorichaya Somparn, Prapin Tharnpoophasiam, Suwalee Worakhunpiset and Supachai Topanurak

    Citation: Proteome Science 2019 17:1

    Content type: Research

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  6. Abiotic stress reduces photosynthetic yield and plant growth, negatively impacting global crop production and is a major constraint faced by agriculture. However, the knowledge on the impact on plants under ex...

    Authors: Débora Parrine, Bo-Sen Wu, Bilal Muhammad, Keith Rivera, Darryl Pappin, Xin Zhao and Mark Lefsrud

    Citation: Proteome Science 2018 16:20

    Content type: Research

    Published on:

  7. Maize seedlings are constantly exposed to inorganic phosphate (Pi)-limited environments. To understand how maize cope with low Pi (LP) and high Pi (HP) conditions, physiological and global proteomic analysis o...

    Authors: Yanling Sun, Chunhua Mu and Xia Liu

    Citation: Proteome Science 2018 16:19

    Content type: Research

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  8. Calcitonin gene-related peptide (CGRP) contributes to bone formation by stimulating bone marrow stromal cell (BMSC) proliferation and differentiation. However, the proliferative and apoptotic effects of CGRP o...

    Authors: Jianqun Wu, Song Liu, Zhao Wang, Shenghui Ma, Huan Meng and Jijie Hu

    Citation: Proteome Science 2018 16:18

    Content type: Research

    Published on:

  9. The non-receptor tyrosine kinase, SRMS (Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites) is a member of the BRK family kinases (BFKs) which represents an evolution...

    Authors: Raghuveera Kumar Goel, Mona Meyer, Marta Paczkowska, Jüri Reimand, Frederick Vizeacoumar, Franco Vizeacoumar, TuKiet T. Lam and Kiven Erique Lukong

    Citation: Proteome Science 2018 16:16

    Content type: Research

    Published on:

  10. The sensory epithelium of the inner ear converts the mechanical energy of sound to electro-chemical energy recognized by the central nervous system. This process is mediated by receptor cells known as hair cel...

    Authors: Lancia N. F. Darville and Bernd H. A. Sokolowski

    Citation: Proteome Science 2018 16:15

    Content type: Research

    Published on:

  11. The practice of dehorning yak raises animal safety concerns, which have been addressed by selective breeding to obtain genetically hornless yak. The POLLED locus in yak has been studied extensively; however, l...

    Authors: Mingna Li, Xiaoyun Wu, Xian Guo, Pengjia Bao, Xuezhi Ding, Min Chu, Chunnian Liang and Ping Yan

    Citation: Proteome Science 2018 16:14

    Content type: Research

    Published on:

  12. Following publication of the original article [1]

    Authors: Christos Spanos, Elaina M. Maldonado, Ciarán P. Fisher, Petchpailin Leenutaphong, Ernesto Oviedo-Orta, David Windridge, Francisco J. Salguero, Alexandra Bermúdez-Fajardo, Mark E. Weeks, Caroline Evans, Bernard M. Corfe, Naila Rabbani, Paul J. Thornalley, Michael H. Miller, Huan Wang, John F. Dillon…

    Citation: Proteome Science 2018 16:13

    Content type: Correction

    Published on:

    The original article was published in Proteome Science 2018 16:4

  13. Fibroblast growth factor receptor 2 (FGFR2) play a vital role in skeletogenesis. However, the molecular mechanisms triggered by FGFR2 in osteoblasts are still not fully understood. In this study, proteomics an...

    Authors: Tianyi Cai, Baojin Wu, Xinjie Tang, Zhaoping Zhou, Junyi Yang, Ronghu Ke and Xiongzheng Mu

    Citation: Proteome Science 2018 16:12

    Content type: Research

    Published on:

  14. The shells of various Haliotis species have served as models of invertebrate biomineralization and physical shell properties for more than 20 years. A focus of this research has been the nacreous inner layer of t...

    Authors: Karlheinz Mann, Nicolas Cerveau, Meike Gummich, Monika Fritz, Matthias Mann and Daniel J. Jackson

    Citation: Proteome Science 2018 16:11

    Content type: Research

    Published on:

  15. Upon publication of the original article [1], Marwa Eltoweissy noticed that her affiliation: “3. Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt” was missing. This affiliati...

    Authors: Gry H. Dihazi, Gerhard A. Mueller, Abdul R. Asif, Marwa Eltoweissy, Johannes T. Wessels and Hassan Dihazi

    Citation: Proteome Science 2018 16:10

    Content type: Correction

    Published on:

    The original article was published in Proteome Science 2015 13:6

  16. Previous studies have shown that lamprey buccal glands contain some regulators related to anticoagulation, nociception, and immune responses due to the blood sucking habit. Regrettably, the protein expression ...

    Authors: Bowen Li, Meng Gou, Jianmei Han, Xiaofei Yuan, Yingying Li, Tiesong Li, Qi Jiang, Rong Xiao and Qingwei Li

    Citation: Proteome Science 2018 16:9

    Content type: Research

    Published on:

  17. Euphorbia lathyris L., a Traditional Chinese medicine (TCM), is commonly used for the treatment of hydropsy, ascites, constipation, amenorrhea, and scabies. Semen Euphorbiae Pulveratum, which is another type of E...

    Authors: Yu Zhang, Yingzi Wang, Shaojing Li, Xiuting Zhang, Wenhua Li, Shengxiu Luo, Zhenyang Sun and Ruijie Nie

    Citation: Proteome Science 2018 16:8

    Content type: Research

    Published on:

  18. The aminoglycoside antibiotic gentamicin is an ototoxic drug and has been used experimentally to investigate cochlear damage induced by noise.

    Authors: Elisa Ghelfi, Yohann Grondin, Emil J. Millet, Adam Bartos, Magda Bortoni, Clara Oliveira Gomes dos Santos, Humberto J. Trevino-Villarreal, Rosalinda Sepulveda and Rick Rogers

    Citation: Proteome Science 2018 16:7

    Content type: Research

    Published on:

  19. The finite marine resources make it difficult for us to obtain enough fish oil (FO) used in aquatic feeds. Another sustainable ingredients should be found to substitute FO. The effects of replacing FO with veg...

    Authors: Banghong Wei, Zhigang Yang, Yongxu Cheng, Jianyi Wang and Junyu Zhou

    Citation: Proteome Science 2018 16:6

    Content type: Research

    Published on:

  20. Protein kinase C ζ (PKCζ), an isoform of the atypical protein kinase C, is a pivotal regulator in cancer. However, the molecular and cellular mechanisms whereby PKCζ regulates tumorigenesis and metastasis are ...

    Authors: Chunyu Hou, Yuan Li, Huiqin Liu, Mengjiao Dang, Guoxuan Qin, Ning Zhang and Ruibing Chen

    Citation: Proteome Science 2018 16:5

    Content type: Research

    Published on:

  21. Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. However, its molecular pathogenesis is incompletely characterized and clinical biomarkers remain scarce. The aims of these ...

    Authors: Christos Spanos, Elaina M. Maldonado, Ciarán P. Fisher, Petchpailin Leenutaphong, Ernesto Oviedo-Orta, David Windridge, Francisco J. Salguero, Alexandra Bermúdez-Fajardo, Mark E. Weeks, Caroline Evans, Bernard M. Corfe, Naila Rabbani, Paul J. Thornalley, Michael H. Miller, Huan Wang, John F. Dillon…

    Citation: Proteome Science 2018 16:4

    Content type: Research

    Published on:

    The Correction to this article has been published in Proteome Science 2018 16:13

  22. Epithelial ovarian cancer is the second most lethal gynecological cancer worldwide. Ascites can be found in all clinical stages, however in advanced disease stages IIIC and IV it is more frequent and could be ...

    Authors: Alfredo Toledo-Leyva, Julio César Villegas-Pineda, Sergio Encarnación-Guevara, Dolores Gallardo-Rincón and Patricia Talamás-Rohana

    Citation: Proteome Science 2018 16:3

    Content type: Research

    Published on:

  23. Acrolein (allyl Aldehyde) as one of smoke irritant exacerbates chronic airway diseases and increased in sputum of patients with asthma and chronic obstructive lung disease. But underlying mechanism remains unr...

    Authors: Pureun-Haneul Lee, Byeong-Gon Kim, Sun-Hye Lee, George D. Leikauf and An-Soo Jang

    Citation: Proteome Science 2018 16:2

    Content type: Research

    Published on:

  24. Fungi are constantly exposed to nitrogen limiting environments, and thus the efficient regulation of nitrogen metabolism is essential for their survival, growth, development and pathogenicity. To understand ho...

    Authors: Yeonyee Oh, Suzanne L. Robertson, Jennifer Parker, David C. Muddiman and Ralph A. Dean

    Citation: Proteome Science 2017 15:20

    Content type: Research

    Published on:

  25. Alfalfa (Medicago sativa) is the most extensively cultivated forage legume in the world, and salinity stress is the most problematic environmental factors limiting alfalfa production. To evaluate alfalfa tissue v...

    Authors: Junbo Xiong, Yan Sun, Qingchuan Yang, Hong Tian, Heshan Zhang, Yang Liu and Mingxin Chen

    Citation: Proteome Science 2017 15:19

    Content type: Research

    Published on:

  26. Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no corre...

    Authors: Carmine Mancone, Alessio Grimaldi, Giulia Refolo, Isabella Abbate, Gabriella Rozera, Dario Benelli, Gian Maria Fimia, Vincenzo Barnaba, Marco Tripodi, Mauro Piacentini and Fabiola Ciccosanti

    Citation: Proteome Science 2017 15:18

    Content type: Research

    Published on:

  27. Identifying selective kinase inhibitors remains a major challenge. The design of bivalent inhibitors provides a rational strategy for accessing potent and selective inhibitors. While bivalent kinase inhibitors...

    Authors: Margaret L. Wong, Jason Murphy, Edmund Harrington, Carrie M. Gower, Rishi K. Jain, Markus Schirle and Jason R. Thomas

    Citation: Proteome Science 2017 15:17

    Content type: Research

    Published on:

  28. Determining small molecule—target protein interaction is essential for the chemical proteomics. One of the most important keys to explore biological system in chemical proteomics field is finding first-class m...

    Authors: Kyungtae Kang, Jongmin Park and Eunha Kim

    Citation: Proteome Science 2017 15:15

    Content type: Review

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  29. Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that are crucial for biomedical research and drug discovery. Various techniques have been used to study specific protei...

    Authors: Dhiraj P. Murale, Seong Cheol Hong, Md. Mamunul Haque and Jun-Seok Lee

    Citation: Proteome Science 2017 15:14

    Content type: Review

    Published on:

  30. Liver models that closely mimic the in vivo microenvironment are useful for understanding liver functions, capabilities, and intercellular communication processes. Three-dimensional (3D) liver models assembled...

    Authors: Lucas T. Vu, Sophia M. Orbach, W. Keith Ray, Margaret E. Cassin, Padmavathy Rajagopalan and Richard F. Helm

    Citation: Proteome Science 2017 15:12

    Content type: Research

    Published on:

  31. Unlike humans, there is currently no publicly available reference mass spectrometry-based circulating acellular proteome data for sheep, limiting the analysis and interpretation of a range of physiological cha...

    Authors: Saul Chemonges, Rajesh Gupta, Paul C. Mills, Steven R. Kopp and Pawel Sadowski

    Citation: Proteome Science 2017 15:11

    Content type: Research

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  32. Drought (Water deficit, WD) poses a serious threat to extensively economic losses of trees throughout the world. Chinese dwarf cherry (Cerasus humilis) is a good perennial plant for studying the physiological and...

    Authors: Zepeng Yin, Jing Ren, Lijuan Zhou, Lina Sun, Jiewan Wang, Yulong Liu and Xingshun Song

    Citation: Proteome Science 2017 15:9

    Content type: Research

    Published on:

  33. Data from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that en...

    Authors: Jonatan Eriksson, Simone Andersson, Roger Appelqvist, Elisabet Wieslander, Mikael Truedsson, May Bugge, Johan Malm, Magnus Dahlbäck, Bo Andersson, Thomas E. Fehniger and György Marko-Varga

    Citation: Proteome Science 2017 15:8

    Content type: Research

    Published on:

  34. Hepatitis B virus (HBV) is a global health problem, and infected patients if left untreated may develop cirrhosis and eventually hepatocellular carcinoma. This study aims to enlighten pathways associated with ...

    Authors: Seyma Katrinli, Kamil Ozdil, Abdurrahman Sahin, Oguzhan Ozturk, Gozde Kir, Ahmet Tarik Baykal, Emel Akgun, Omer Sinan Sarac, Mehmet Sokmen, H. Levent Doğanay and Gizem Dinler Doğanay

    Citation: Proteome Science 2017 15:7

    Content type: Research

    Published on:

  35. Reactive oxygen species (ROS) production is an early event in the immune response of plants. ROS production affects the redox-based modification of cysteine residues in redox proteins, which contribute to prot...

    Authors: Kazuko Morino, Mayumi Kimizu and Masayuki Fujiwara

    Citation: Proteome Science 2017 15:6

    Content type: Research

    Published on:

  36. Malaria continues to be a great public health concern due to the significant mortality and morbidity associated with the disease especially in developing countries. Microparticles (MPs), also called plasma mem...

    Authors: Samuel Antwi-Baffour, Jonathan Kofi Adjei, Francis Agyemang-Yeboah, Max Annani-Akollor, Ransford Kyeremeh, George Awuku Asare and Ben Gyan

    Citation: Proteome Science 2017 15:5

    Content type: Research

    Published on:

  37. Eggshells which consist largely of calcareous outer shell and shell membranes, constitute a significant part of poultry hatchery waste. The shell membranes (ESM) not only contain proteins that originate from e...

    Authors: N. C. Rath, R. Liyanage, S. K. Makkar and J. O. Lay Jr.

    Citation: Proteome Science 2017 15:4

    Content type: Research

    Published on:

  38. Non-starch polysaccharide enzymes (NSPEs) have long been used in monogastric animal feed production to degrade non-starch polysaccharides (NSPs) to oligosaccharides in order to promote growth performance and g...

    Authors: Jize Zhang, Yang Gao, Qingping Lu, Renna Sa and Hongfu Zhang

    Citation: Proteome Science 2017 15:3

    Content type: Research

    Published on:

  39. The degradation of the steppe of Inner Mongolia, due to overgrazing, has resulted in ecosystem damage as well as extensive reductions in sheep production. The growth performance of sheep is greatly reduced bec...

    Authors: Weibo Ren, Xiangyang Hou, Yuqing Wang, Warwick Badgery, Xiliang Li, Yong Ding, Huiqin Guo, Zinian Wu, Ningning Hu, Lingqi Kong, Chun Chang, Chao Jiang and Jize Zhang

    Citation: Proteome Science 2017 15:2

    Content type: Research

    Published on:

  40. Proteomic matrix-assisted laser desorption/ionisation (MALDI) linear time-of-flight (TOF) mass spectrometry (MS) may be used to produce protein profiles from biological samples with the aim of discovering biom...

    Authors: Tyman E. Stanford, Christopher J. Bagley and Patty J. Solomon

    Citation: Proteome Science 2016 14:19

    Content type: Methodology

    Published on:

  41. Myoglobin (Mb) is a sarcoplasmic heme protein primarily responsible for meat color and its chemistry is species specific. 4-hydroxy-2-nonenal (HNE) is a cytotoxic lipid derived aldehyde detected in meat and wa...

    Authors: Naveena B. Maheswarappa, K. Usha Rani, Y. Praveen Kumar, Vinayak V. Kulkarni and Srikanth Rapole

    Citation: Proteome Science 2016 14:18

    Content type: Research

    Published on:

  42. Human follicular fluid (FF) is a unique biological fluid in which the oocyte develops in vivo, and presents an optimal source for non-invasive biochemical predictors. Oocyte quality directly influences the emb...

    Authors: Fang Chen, Carl Spiessens, Thomas D’Hooghe, Karen Peeraer and Sebastien Carpentier

    Citation: Proteome Science 2016 14:17

    Content type: Research

    Published on:

  43. Daurian ground squirrels (Spermophilus dauricus) deviate from significant increase of protein catabolism and loss of myofibrillar contents during long period of hibernation inactivity.

    Authors: Hui Chang, Shan-Feng Jiang, Kai Dang, Hui-Ping Wang, Shen-Hui Xu and Yun-Fang Gao

    Citation: Proteome Science 2016 14:16

    Content type: Research

    Published on:

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