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  1. Cervical intraepithelial neoplasia (CIN) grades 2 and 3 are usually grouped and treated in the same way as "high grade", in spite of their different risk to cancer progression and spontaneous regression rates....

    Authors: Kai-Erik Uleberg, Ane Cecilie Munk, Cato Brede, Einar Gudlaugsson, Bianca van Diermen, Ivar Skaland, Anais Malpica, Emiel AM Janssen, Anne Hjelle and Jan PA Baak
    Citation: Proteome Science 2011 9:36
  2. A large variety of proteins involved in inflammation, coagulation, lipid-oxidation and lipid metabolism have been associated with high-density lipoprotein (HDL) and it is anticipated that changes in the HDL pr...

    Authors: Johannes HM Levels, Pierre Geurts, Helen Karlsson, Raphaël Marée, Stefan Ljunggren, Louise Fornander, Louis Wehenkel, Mats Lindahl, Erik SG Stroes, Jan A Kuivenhoven and Joost CM Meijers
    Citation: Proteome Science 2011 9:34
  3. Cytokinin is a plant hormone that plays a crucial role in several processes of plant growth and development. In recent years, major breakthroughs have been achieved in the elucidation of the metabolism, the si...

    Authors: Anne Cortleven, Jean-Paul Noben and Roland Valcke
    Citation: Proteome Science 2011 9:33
  4. Actinobacillus pleuropneumoniae (APP) is one of the most important swine pathogens worldwide. Identification and characterization of novel antigenic APP vaccine candidates are underway. In the present study, we ...

    Authors: Wei Zhang, Jing Shao, Guangjin Liu, Fang Tang, Yan Lu, Zhipeng Zhai, Yang Wang, Zongfu Wu, Huochun Yao and Chengping Lu
    Citation: Proteome Science 2011 9:32
  5. Diagnosis of esophageal squamous cell carcinoma (SCC) may improve with early diagnosis. Currently it is difficult to diagnose SCC in the early stage because there is a limited number of tumor markers available.

    Authors: Akiko Kagaya, Hideaki Shimada, Tooru Shiratori, Mari Kuboshima, Kazue Nakashima-Fujita, Mari Yasuraoka, Takanori Nishimori, Shunsuke Kurei, Takahisa Hachiya, Akihiro Murakami, Yutaka Tamura, Fumio Nomura, Takenori Ochiai, Hisahiro Matsubara, Masaki Takiguchi and Takaki Hiwasa
    Citation: Proteome Science 2011 9:31
  6. Mass spectrometry-based proteomics has reached a stage where it is possible to comprehensively analyze the whole proteome of a cell in one experiment. Here, the employment of stable isotopes has become a stand...

    Authors: Stefan P Albaum, Hannes Hahne, Andreas Otto, Ute Haußmann, Dörte Becher, Ansgar Poetsch, Alexander Goesmann and Tim W Nattkemper
    Citation: Proteome Science 2011 9:30
  7. Proteomic research in the field of parathyroid tissues is limited by the very small dimension of the glands and by the low incidence of cancer lesions (1%). Formalin-fixed paraffin-embedded (FFPE) tissue speci...

    Authors: Elena Donadio, Laura Giusti, Filomena Cetani, Ylenia Da Valle, Federica Ciregia, Gino Giannaccini, Elena Pardi, Federica Saponaro, Liborio Torregrossa, Fulvio Basolo, Claudio Marcocci and Antonio Lucacchini
    Citation: Proteome Science 2011 9:29
  8. In vitro maturation (IVM) of mammalian oocytes is divided into the GV (germinal vesicle stage), MI (metaphase I stage) and MII (metaphase II stage) stages, and only fully mature oocytes have acquired the abili...

    Authors: Jumi Kim, Ji-Su Kim, Young-Joo Jeon, Dong-Wook Kim, Tae-Ho Yang, Yunjo Soh, Hak Kyo Lee, Nag-Jin Choi, Soo-Bong Park, Kang Seok Seo, Hyung Min Chung, Dong-Seok Lee and Jung-Il Chae
    Citation: Proteome Science 2011 9:28
  9. An encouraging approach for the diagnosis and effective therapy of immunological pathologies, which would include cancer, is the identification of proteins and phosphorylated proteins. Disease proteomics, in p...

    Authors: Elena López, Isabel López, Antonio Ferreira and Julia Sequí
    Citation: Proteome Science 2011 9:27

    The Retraction Note to this article has been published in Proteome Science 2013 11:16

  10. Strawberries (Fragaria ananassa) reproduce asexually through stolons, which have strong tendencies to form adventitious roots at their second node. Understanding how the development of the proximal (I-1) and dist...

    Authors: Xianping Fang, Huasheng Ma, Dezhao Lu, Hong Yu, Wenguo Lai and Songlin Ruan
    Citation: Proteome Science 2011 9:26
  11. Atherosclerosis is considered the major cause of the dramatic increase in cardiovascular mortality among patients suffering from chronic kidney disease (CKD). Although the close connection between atherosclero...

    Authors: Magdalena Luczak, Dorota Formanowicz, Elzbieta Pawliczak, Maria Wanic-Kossowska, Andrzej Wykretowicz and Marek Figlerowicz
    Citation: Proteome Science 2011 9:25
  12. High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been test...

    Authors: Bin Liu, Fang-hua Qiu, Courtney Voss, Yun Xu, Ming-zhe Zhao, Yan-xin Wu, Jing Nie and Zi-lian Wang
    Citation: Proteome Science 2011 9:24
  13. Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes. A DIVA subunit vaccine comprised o...

    Authors: Falk FR Buettner, Sarah A Konze, Alexander Maas and Gerald F Gerlach
    Citation: Proteome Science 2011 9:23
  14. Proteomics may help us better understand the changes of multiple proteins involved in oncogenesis and progression of prostate cancer(PCa) and identify more diagnostic and prognostic biomarkers. The aim of this...

    Authors: Chuanyu Sun, Chao Song, Zhicheng Ma, Ke Xu, Yang Zhang, Hong Jin, Shijun Tong, Weihong Ding, Guowei Xia and Qiang Ding
    Citation: Proteome Science 2011 9:22
  15. Bladder transitional cell carcinoma (BTCC) is the fourth most frequent neoplasia in men, clinically characterized by high recurrent rates and poor prognosis. Availability of urinary tumor biomarkers represents...

    Authors: Hongjie Li, Changying Li, Huili Wu, Ting Zhang, Jin Wang, Shixin Wang and Jiwu Chang
    Citation: Proteome Science 2011 9:21
  16. Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SELDI-TOF-MS) is a frequently used technique for cancer biomarker research. The specificity of biomarkers detected by SELDI can be...

    Authors: Pei-Sung Hsu, Yu-Shan Wang, Su-Chen Huang, Yi-Hsien Lin, Chih-Chia Chang, Yuk-Wah Tsang, Jiunn-Song Jiang, Shang-Jyh Kao, Wu-Ching Uen and Kwan-Hwa Chi
    Citation: Proteome Science 2011 9:20
  17. Serum is an ideal source of biomarker discovery and proteomic profiling studies are continuously pursued on serum samples. However, serum is featured by high level of protein glycosylations that often cause io...

    Authors: Atsuhiko Toyama, Hidewaki Nakagawa, Koichi Matsuda, Nobuhisa Ishikawa, Nobuoki Kohno, Yataro Daigo, Taka-Aki Sato, Yusuke Nakamura and Koji Ueda
    Citation: Proteome Science 2011 9:18
  18. Low-abundance proteins are difficultly observed on the two-dimensional gel electrophoresis (2-DE) maps of urine proteome, because they are usually obscured by high-abundance proteins such as albumin and immuno...

    Authors: Chih-Ming Lu, Yu-Jen Wu, Cheng-Chi Chen, Jue-Liang Hsu, Jiing-Chuan Chen, Jeff Yi-Fu Chen, Chun-Hsiung Huang and Ying-Chin Ko
    Citation: Proteome Science 2011 9:17
  19. Genomics, transcriptomics and proteomics of glioblastoma multiforme (GBM) have recently emerged as possible tools to discover therapeutic targets and biomarkers for new therapies including immunotherapy. It is...

    Authors: Brigitte Collet, Nathalie Guitton, Stephan Saïkali, Tony Avril, Charles Pineau, Abderrahmane Hamlat, Jean Mosser and Véronique Quillien
    Citation: Proteome Science 2011 9:16
  20. Suitable biomarkers associated with the development of delirium are still not known. Urinary proteomics has successfully been applied to identify novel biomarkers associated with various disease states, but it...

    Authors: Mark van den Boogaard, Rachel PL van Swelm, Frans GM Russel, Suzanne Heemskerk, Johannes G van der Hoeven, Rosalinde Masereeuw and Peter Pickkers
    Citation: Proteome Science 2011 9:13
  21. Total soluble proteome alterations of white rot fungus Phanerochaete chrysosporium in response to different doses (25, 50 and 100 μM) of Pb (II) were characterized by 2DE in combination with MALDI-TOF-MS.

    Authors: Volkan Yıldırım, Servet Özcan, Dörte Becher, Knut Büttner, Michael Hecker and Gülay Özcengiz
    Citation: Proteome Science 2011 9:12
  22. Avian infectious bronchitis (IB) is one of the most serious diseases of economic importance in chickens; it is caused by the avian infectious coronavirus (IBV). Information remains limited about the comparativ...

    Authors: Zhongzan Cao, Zongxi Han, Yuhao Shao, Heyuan Geng, Xiangang Kong and Shengwang Liu
    Citation: Proteome Science 2011 9:11
  23. Wheat flour is one of the world's major food ingredients, in part because of the unique end-use qualities conferred by the abundant glutamine- and proline-rich gluten proteins. Many wheat flour proteins also p...

    Authors: Frances M Dupont, William H Vensel, Charlene K Tanaka, William J Hurkman and Susan B Altenbach
    Citation: Proteome Science 2011 9:10
  24. Labeling whole Arabidopsis (Arabidopsis thaliana) plants to high enrichment with 13C for proteomics and metabolomics applications would facilitate experimental approaches not possible by conventional methods. Suc...

    Authors: Wen-Ping Chen, Xiao-Yuan Yang, Geoffrey L Harms, William M Gray, Adrian D Hegeman and Jerry D Cohen
    Citation: Proteome Science 2011 9:9
  25. The aqueous humor (AH), a liquid of the anterior and posterior chamber of the eye, comprises many proteins with various roles and important biological functions. Many of these proteins have not been identified...

    Authors: Miroslava Stastna, Ashley Behrens, Peter J McDonnell and Jennifer E Van Eyk
    Citation: Proteome Science 2011 9:8
  26. Transmissible spongiform encephalopathy diseases are untreatable, uniformly fatal degenerative syndromes of the central nervous system that can be transmitted both within as well as between species. The bovine...

    Authors: Margot Plews, Lise Lamoureux, Sharon LR Simon, Catherine Graham, Viola Ruddat, Stefanie Czub and J David Knox
    Citation: Proteome Science 2011 9:6
  27. Hepatitis E is endemic to resource-poor regions, where it manifests as sporadic cases and large waterborne outbreaks. The disease severity ranges from acute self-limited hepatitis with low mortality to fulmina...

    Authors: Shikha Taneja, Imran Ahmad, Somdutta Sen, Saravanan Kumar, Reena Arora, Vijay K Gupta, Rakesh Aggarwal, Krishnamoorthy Narayanasamy, Vanga S Reddy and Shahid Jameel
    Citation: Proteome Science 2011 9:5
  28. Airway surface liquid, often referred to as mucus, is a thin layer of fluid covering the luminal surface that plays an important defensive role against foreign particles and chemicals entering the lungs. Airwa...

    Authors: Mehboob Ali, Erik P Lillehoj, Yongsung Park, Yoshiyuki Kyo and K Chul Kim
    Citation: Proteome Science 2011 9:4
  29. Hair bulge progenitor cells (HBPCs) are multipotent stem cells derived from the bulge region of mice vibrissal hairs. The purified HBPCs express CD34, K15 and K14 surface markers. It has been reported that HBP...

    Authors: Winifred WY Yau, Mei Kuen Tang, Elve Chen, YaoYao, Ivan WC Wong, Henry SS Lee and Kenneth KH Lee
    Citation: Proteome Science 2011 9:3
  30. We describe a method to identify metabolites of proteins that eliminates endogenous background by using stable isotope labeled matrices. This technique allows selective screening of the intact therapeutic mole...

    Authors: Charles B Reilly, Sri H Ramarathinam, Nicholas A Williamson and Anthony W Purcell
    Citation: Proteome Science 2011 9:2
  31. C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentameric protein in plasma. Recently, a potential dissociation mechanism from the disc-shaped pentameric CRP (pCRP) into sin...

    Authors: Steffen U Eisenhardt, Jonathon Habersberger, Karen Oliva, Graeme I Lancaster, Mustafa Ayhan, Kevin J Woollard, Holger Bannasch, Greg E Rice and Karlheinz Peter
    Citation: Proteome Science 2011 9:1
  32. Reverse phase protein arrays (RPPA) have been demonstrated to be a useful experimental platform for quantitative protein profiling in a high-throughput format. Target protein detection relies on the readout ob...

    Authors: Heiko A Mannsperger, Stefan Uhlmann, Christian Schmidt, Stefan Wiemann, Özgür Sahin and Ulrike Korf
    Citation: Proteome Science 2010 8:69
  33. Citrus is one of the most important and widely grown commodity fruit crops. In this study a label-free LC-MS/MS based shot-gun proteomics approach was taken to explore three main stages of citrus fruit develop...

    Authors: Ehud Katz, Mario Fon, Richard A Eigenheer, Brett S Phinney, Joseph N Fass, Dawei Lin, Avi Sadka and Eduardo Blumwald
    Citation: Proteome Science 2010 8:68
  34. Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables that exerts anti-oxidant, anti-inflammatory, anti-cancer and radio-sensitizing activities. Nonetheless, the mechanism responsible for SFN...

    Authors: Chan-Hee Lee, Soo-Jin Jeong, Sun-Mi Yun, Ji-Hyun Kim, Hyo-Jung Lee, Kwang Seok Ahn, Suk-Hyun Won, Hyun Seok Kim, Hyo-Jeong Lee, Kyoo-Seok Ahn, Shudong Zhu, Chang-Yan Chen and Sung-Hoon Kim
    Citation: Proteome Science 2010 8:67
  35. Numerous gel-based softwares exist to detect protein changes potentially associated with disease. The data, however, are abundant with technical and structural complexities, making statistical analysis a diffi...

    Authors: Jeffrey C Miecznikowski, Senthilkumar Damodaran, Kimberly F Sellers and Richard A Rabin
    Citation: Proteome Science 2010 8:66
  36. Previous studies suggested that dietary tannin ingestion may induce changes in mouse salivary proteins in addition to the primarily studied proline-rich proteins (PRPs). The aim of the present study was to det...

    Authors: Elsa Lamy, Gonçalo Graça, Gonçalo da Costa, Catarina Franco, Fernando Capela e Silva, Elvira Sales Baptista and Ana Varela Coelho
    Citation: Proteome Science 2010 8:65
  37. Restoration of rooting competence is important for rejuvenation in Sequoia sempervirens (D. Don) Endl and is achieved by repeatedly grafting Sequoia shoots after 16 and 30 years of cultivation in vitro.

    Authors: Ing-Feng Chang, Peng-Jen Chen, Chin-Hui Shen, Tsung-Ju Hsieh, Ya-Wen Hsu, Bau-Lian Huang, Ching-I Kuo, Yu-Ting Chen, Hsiu-An Chu, Kai-Wun Yeh and Li-Chun Huang
    Citation: Proteome Science 2010 8:64
  38. Cervicovaginal fluid has an important function in the homeostasis and immunity of the lower female genital tract. Analysis of the cervicovaginal fluid proteome may therefore yield important information about t...

    Authors: Geert Zegels, Geert AA Van Raemdonck, Wiebren AA Tjalma and Xaveer WM Van Ostade
    Citation: Proteome Science 2010 8:63
  39. The removal of high-abundance proteins from plasma is an efficient approach to investigating flow-through proteins for biomarker discovery studies. Most depletion methods are based on multiple immunoaffinity m...

    Authors: Kyunggon Kim, Jiyoung Yu, Hophil Min, Hyunsoo Kim, Byungwook Kim, Hyeong Gon Yu and Youngsoo Kim
    Citation: Proteome Science 2010 8:62
  40. Protein biomarkers will play a pivotal role in the future of personalized medicine for both diagnosis and treatment decision-making. While the results of several pre-clinical and small-scale clinical studies h...

    Authors: C Bart Rountree, Colleen A Van Kirk, Hanning You, Wei Ding, Hien Dang, Heather D VanGuilder and Willard M Freeman
    Citation: Proteome Science 2010 8:61
  41. Sporulation, characteristic for some bacteria such as Bacillus subtilis, has not been entirely defined yet. Protein phosphatase E (PrpE) and small, acid soluble spore proteins (SASPs) influence this process. Neve...

    Authors: Katarzyna Macur, Caterina Temporini, Gabriella Massolini, Jolanta Grzenkowicz-Wydra, Michał Obuchowski and Tomasz Bączek
    Citation: Proteome Science 2010 8:60
  42. Streptomycin (SM) is a broad spectrum antibiotic and is an important component of any anti-tuberculosis therapy regimen. Several mechanisms have been proposed to explain the emergence of resistance but still o...

    Authors: Prashant Sharma, Bhavnesh Kumar, Yash Gupta, Neelja Singhal, Vishwa Mohan Katoch, Krishnamurthy Venkatesan and Deepa Bisht
    Citation: Proteome Science 2010 8:59
  43. Diagnosis of ovarian carcinoma is in urgent need for new complementary biomarkers for early stage detection. Proteins that are aberrantly excreted in the urine of cancer patients are excellent biomarker candid...

    Authors: Siti S Abdullah-Soheimi, Boon-Kiong Lim, Onn H Hashim and Adawiyah S Shuib
    Citation: Proteome Science 2010 8:58
  44. Brain capillary endothelial cells (BCECs) form the physiological basis of the blood-brain barrier (BBB). The barrier function is (at least in part) due to well-known proteins such as transporters, tight juncti...

    Authors: Gwënaël Pottiez, Barbara Deracinois, Sophie Duban-Deweer, Roméo Cecchelli, Laurence Fenart, Yannis Karamanos and Christophe Flahaut
    Citation: Proteome Science 2010 8:57
  45. Platelets are small anucleated blood particles that play a key role in the control of bleeding. Platelets need to be activated to perform their functions and participate in hemostasis. The process of activatio...

    Authors: Pavel Májek, Zuzana Reicheltová, Jana Štikarová, Jiří Suttnar, Alžběta Sobotková and Jan E Dyr
    Citation: Proteome Science 2010 8:56

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