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Page 9 of 13

  1. High abundance protein depletion is a major challenge in the study of serum/plasma proteomics. Prior to this study, most commercially available kits for depletion of highly abundant proteins had only been test...

    Authors: Bin Liu, Fang-hua Qiu, Courtney Voss, Yun Xu, Ming-zhe Zhao, Yan-xin Wu, Jing Nie and Zi-lian Wang

    Citation: Proteome Science 2011 9:24

    Content type: Research

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  2. Protection of pigs by vaccination against Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia, is hampered by the presence of 15 different serotypes. A DIVA subunit vaccine comprised o...

    Authors: Falk FR Buettner, Sarah A Konze, Alexander Maas and Gerald F Gerlach

    Citation: Proteome Science 2011 9:23

    Content type: Research

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  3. Proteomics may help us better understand the changes of multiple proteins involved in oncogenesis and progression of prostate cancer(PCa) and identify more diagnostic and prognostic biomarkers. The aim of this...

    Authors: Chuanyu Sun, Chao Song, Zhicheng Ma, Ke Xu, Yang Zhang, Hong Jin, Shijun Tong, Weihong Ding, Guowei Xia and Qiang Ding

    Citation: Proteome Science 2011 9:22

    Content type: Research

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  4. Bladder transitional cell carcinoma (BTCC) is the fourth most frequent neoplasia in men, clinically characterized by high recurrent rates and poor prognosis. Availability of urinary tumor biomarkers represents...

    Authors: Hongjie Li, Changying Li, Huili Wu, Ting Zhang, Jin Wang, Shixin Wang and Jiwu Chang

    Citation: Proteome Science 2011 9:21

    Content type: Research

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  5. Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (SELDI-TOF-MS) is a frequently used technique for cancer biomarker research. The specificity of biomarkers detected by SELDI can be...

    Authors: Pei-Sung Hsu, Yu-Shan Wang, Su-Chen Huang, Yi-Hsien Lin, Chih-Chia Chang, Yuk-Wah Tsang, Jiunn-Song Jiang, Shang-Jyh Kao, Wu-Ching Uen and Kwan-Hwa Chi

    Citation: Proteome Science 2011 9:20

    Content type: Research

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  6. Serum is an ideal source of biomarker discovery and proteomic profiling studies are continuously pursued on serum samples. However, serum is featured by high level of protein glycosylations that often cause io...

    Authors: Atsuhiko Toyama, Hidewaki Nakagawa, Koichi Matsuda, Nobuhisa Ishikawa, Nobuoki Kohno, Yataro Daigo, Taka-Aki Sato, Yusuke Nakamura and Koji Ueda

    Citation: Proteome Science 2011 9:18

    Content type: Research

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  7. Low-abundance proteins are difficultly observed on the two-dimensional gel electrophoresis (2-DE) maps of urine proteome, because they are usually obscured by high-abundance proteins such as albumin and immuno...

    Authors: Chih-Ming Lu, Yu-Jen Wu, Cheng-Chi Chen, Jue-Liang Hsu, Jiing-Chuan Chen, Jeff Yi-Fu Chen, Chun-Hsiung Huang and Ying-Chin Ko

    Citation: Proteome Science 2011 9:17

    Content type: Methodology

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  8. Genomics, transcriptomics and proteomics of glioblastoma multiforme (GBM) have recently emerged as possible tools to discover therapeutic targets and biomarkers for new therapies including immunotherapy. It is...

    Authors: Brigitte Collet, Nathalie Guitton, Stephan Saïkali, Tony Avril, Charles Pineau, Abderrahmane Hamlat, Jean Mosser and Véronique Quillien

    Citation: Proteome Science 2011 9:16

    Content type: Research

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  9. Suitable biomarkers associated with the development of delirium are still not known. Urinary proteomics has successfully been applied to identify novel biomarkers associated with various disease states, but it...

    Authors: Mark van den Boogaard, Rachel PL van Swelm, Frans GM Russel, Suzanne Heemskerk, Johannes G van der Hoeven, Rosalinde Masereeuw and Peter Pickkers

    Citation: Proteome Science 2011 9:13

    Content type: Research

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  10. Total soluble proteome alterations of white rot fungus Phanerochaete chrysosporium in response to different doses (25, 50 and 100 μM) of Pb (II) were characterized by 2DE in combination with MALDI-TOF-MS.

    Authors: Volkan Yıldırım, Servet Özcan, Dörte Becher, Knut Büttner, Michael Hecker and Gülay Özcengiz

    Citation: Proteome Science 2011 9:12

    Content type: Research

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  11. Avian infectious bronchitis (IB) is one of the most serious diseases of economic importance in chickens; it is caused by the avian infectious coronavirus (IBV). Information remains limited about the comparativ...

    Authors: Zhongzan Cao, Zongxi Han, Yuhao Shao, Heyuan Geng, Xiangang Kong and Shengwang Liu

    Citation: Proteome Science 2011 9:11

    Content type: Research

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  12. Wheat flour is one of the world's major food ingredients, in part because of the unique end-use qualities conferred by the abundant glutamine- and proline-rich gluten proteins. Many wheat flour proteins also p...

    Authors: Frances M Dupont, William H Vensel, Charlene K Tanaka, William J Hurkman and Susan B Altenbach

    Citation: Proteome Science 2011 9:10

    Content type: Research

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  13. Labeling whole Arabidopsis (Arabidopsis thaliana) plants to high enrichment with 13C for proteomics and metabolomics applications would facilitate experimental approaches not possible by conventional methods. Suc...

    Authors: Wen-Ping Chen, Xiao-Yuan Yang, Geoffrey L Harms, William M Gray, Adrian D Hegeman and Jerry D Cohen

    Citation: Proteome Science 2011 9:9

    Content type: Methodology

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  14. The aqueous humor (AH), a liquid of the anterior and posterior chamber of the eye, comprises many proteins with various roles and important biological functions. Many of these proteins have not been identified...

    Authors: Miroslava Stastna, Ashley Behrens, Peter J McDonnell and Jennifer E Van Eyk

    Citation: Proteome Science 2011 9:8

    Content type: Research

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  15. Transmissible spongiform encephalopathy diseases are untreatable, uniformly fatal degenerative syndromes of the central nervous system that can be transmitted both within as well as between species. The bovine...

    Authors: Margot Plews, Lise Lamoureux, Sharon LR Simon, Catherine Graham, Viola Ruddat, Stefanie Czub and J David Knox

    Citation: Proteome Science 2011 9:6

    Content type: Research

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  16. Hepatitis E is endemic to resource-poor regions, where it manifests as sporadic cases and large waterborne outbreaks. The disease severity ranges from acute self-limited hepatitis with low mortality to fulmina...

    Authors: Shikha Taneja, Imran Ahmad, Somdutta Sen, Saravanan Kumar, Reena Arora, Vijay K Gupta, Rakesh Aggarwal, Krishnamoorthy Narayanasamy, Vanga S Reddy and Shahid Jameel

    Citation: Proteome Science 2011 9:5

    Content type: Research

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  17. Airway surface liquid, often referred to as mucus, is a thin layer of fluid covering the luminal surface that plays an important defensive role against foreign particles and chemicals entering the lungs. Airwa...

    Authors: Mehboob Ali, Erik P Lillehoj, Yongsung Park, Yoshiyuki Kyo and K Chul Kim

    Citation: Proteome Science 2011 9:4

    Content type: Research

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  18. Hair bulge progenitor cells (HBPCs) are multipotent stem cells derived from the bulge region of mice vibrissal hairs. The purified HBPCs express CD34, K15 and K14 surface markers. It has been reported that HBP...

    Authors: Winifred WY Yau, Mei Kuen Tang, Elve Chen, YaoYao, Ivan WC Wong, Henry SS Lee and Kenneth KH Lee

    Citation: Proteome Science 2011 9:3

    Content type: Research

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  19. We describe a method to identify metabolites of proteins that eliminates endogenous background by using stable isotope labeled matrices. This technique allows selective screening of the intact therapeutic mole...

    Authors: Charles B Reilly, Sri H Ramarathinam, Nicholas A Williamson and Anthony W Purcell

    Citation: Proteome Science 2011 9:2

    Content type: Methodology

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  20. C-reactive protein (CRP) is a predictor of cardiovascular risk. It circulates as a pentameric protein in plasma. Recently, a potential dissociation mechanism from the disc-shaped pentameric CRP (pCRP) into sin...

    Authors: Steffen U Eisenhardt, Jonathon Habersberger, Karen Oliva, Graeme I Lancaster, Mustafa Ayhan, Kevin J Woollard, Holger Bannasch, Greg E Rice and Karlheinz Peter

    Citation: Proteome Science 2011 9:1

    Content type: Research

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  21. Reverse phase protein arrays (RPPA) have been demonstrated to be a useful experimental platform for quantitative protein profiling in a high-throughput format. Target protein detection relies on the readout ob...

    Authors: Heiko A Mannsperger, Stefan Uhlmann, Christian Schmidt, Stefan Wiemann, Özgür Sahin and Ulrike Korf

    Citation: Proteome Science 2010 8:69

    Content type: Methodology

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  22. Citrus is one of the most important and widely grown commodity fruit crops. In this study a label-free LC-MS/MS based shot-gun proteomics approach was taken to explore three main stages of citrus fruit develop...

    Authors: Ehud Katz, Mario Fon, Richard A Eigenheer, Brett S Phinney, Joseph N Fass, Dawei Lin, Avi Sadka and Eduardo Blumwald

    Citation: Proteome Science 2010 8:68

    Content type: Research

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  23. Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables that exerts anti-oxidant, anti-inflammatory, anti-cancer and radio-sensitizing activities. Nonetheless, the mechanism responsible for SFN...

    Authors: Chan-Hee Lee, Soo-Jin Jeong, Sun-Mi Yun, Ji-Hyun Kim, Hyo-Jung Lee, Kwang Seok Ahn, Suk-Hyun Won, Hyun Seok Kim, Hyo-Jeong Lee, Kyoo-Seok Ahn, Shudong Zhu, Chang-Yan Chen and Sung-Hoon Kim

    Citation: Proteome Science 2010 8:67

    Content type: Research

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  24. Numerous gel-based softwares exist to detect protein changes potentially associated with disease. The data, however, are abundant with technical and structural complexities, making statistical analysis a diffi...

    Authors: Jeffrey C Miecznikowski, Senthilkumar Damodaran, Kimberly F Sellers and Richard A Rabin

    Citation: Proteome Science 2010 8:66

    Content type: Research

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  25. Previous studies suggested that dietary tannin ingestion may induce changes in mouse salivary proteins in addition to the primarily studied proline-rich proteins (PRPs). The aim of the present study was to det...

    Authors: Elsa Lamy, Gonçalo Graça, Gonçalo da Costa, Catarina Franco, Fernando Capela e Silva, Elvira Sales Baptista and Ana Varela Coelho

    Citation: Proteome Science 2010 8:65

    Content type: Research

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  26. Restoration of rooting competence is important for rejuvenation in Sequoia sempervirens (D. Don) Endl and is achieved by repeatedly grafting Sequoia shoots after 16 and 30 years of cultivation in vitro.

    Authors: Ing-Feng Chang, Peng-Jen Chen, Chin-Hui Shen, Tsung-Ju Hsieh, Ya-Wen Hsu, Bau-Lian Huang, Ching-I Kuo, Yu-Ting Chen, Hsiu-An Chu, Kai-Wun Yeh and Li-Chun Huang

    Citation: Proteome Science 2010 8:64

    Content type: Research

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  27. Cervicovaginal fluid has an important function in the homeostasis and immunity of the lower female genital tract. Analysis of the cervicovaginal fluid proteome may therefore yield important information about t...

    Authors: Geert Zegels, Geert AA Van Raemdonck, Wiebren AA Tjalma and Xaveer WM Van Ostade

    Citation: Proteome Science 2010 8:63

    Content type: Review

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  28. The removal of high-abundance proteins from plasma is an efficient approach to investigating flow-through proteins for biomarker discovery studies. Most depletion methods are based on multiple immunoaffinity m...

    Authors: Kyunggon Kim, Jiyoung Yu, Hophil Min, Hyunsoo Kim, Byungwook Kim, Hyeong Gon Yu and Youngsoo Kim

    Citation: Proteome Science 2010 8:62

    Content type: Methodology

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  29. Protein biomarkers will play a pivotal role in the future of personalized medicine for both diagnosis and treatment decision-making. While the results of several pre-clinical and small-scale clinical studies h...

    Authors: C Bart Rountree, Colleen A Van Kirk, Hanning You, Wei Ding, Hien Dang, Heather D VanGuilder and Willard M Freeman

    Citation: Proteome Science 2010 8:61

    Content type: Research

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  30. Sporulation, characteristic for some bacteria such as Bacillus subtilis, has not been entirely defined yet. Protein phosphatase E (PrpE) and small, acid soluble spore proteins (SASPs) influence this process. Neve...

    Authors: Katarzyna Macur, Caterina Temporini, Gabriella Massolini, Jolanta Grzenkowicz-Wydra, Michał Obuchowski and Tomasz Bączek

    Citation: Proteome Science 2010 8:60

    Content type: Research

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  31. Streptomycin (SM) is a broad spectrum antibiotic and is an important component of any anti-tuberculosis therapy regimen. Several mechanisms have been proposed to explain the emergence of resistance but still o...

    Authors: Prashant Sharma, Bhavnesh Kumar, Yash Gupta, Neelja Singhal, Vishwa Mohan Katoch, Krishnamurthy Venkatesan and Deepa Bisht

    Citation: Proteome Science 2010 8:59

    Content type: Research

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  32. Diagnosis of ovarian carcinoma is in urgent need for new complementary biomarkers for early stage detection. Proteins that are aberrantly excreted in the urine of cancer patients are excellent biomarker candid...

    Authors: Siti S Abdullah-Soheimi, Boon-Kiong Lim, Onn H Hashim and Adawiyah S Shuib

    Citation: Proteome Science 2010 8:58

    Content type: Research

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  33. Brain capillary endothelial cells (BCECs) form the physiological basis of the blood-brain barrier (BBB). The barrier function is (at least in part) due to well-known proteins such as transporters, tight juncti...

    Authors: Gwënaël Pottiez, Barbara Deracinois, Sophie Duban-Deweer, Roméo Cecchelli, Laurence Fenart, Yannis Karamanos and Christophe Flahaut

    Citation: Proteome Science 2010 8:57

    Content type: Research

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  34. Platelets are small anucleated blood particles that play a key role in the control of bleeding. Platelets need to be activated to perform their functions and participate in hemostasis. The process of activatio...

    Authors: Pavel Májek, Zuzana Reicheltová, Jana Štikarová, Jiří Suttnar, Alžběta Sobotková and Jan E Dyr

    Citation: Proteome Science 2010 8:56

    Content type: Research

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  35. Citrus canker is a disease caused by Xantomonas citri subsp.citri (Xac), and has emerged as one of the major threats to the worldwide citrus crop because it affects all commercial citrus varieties, decreases the ...

    Authors: Márcia R Soares, Agda P Facincani, Rafael M Ferreira, Leandro M Moreira, Julio CF de Oliveira, Jesus A Ferro, Maria IT Ferro, Rogério Meneghini and Fábio C Gozzo

    Citation: Proteome Science 2010 8:55

    Content type: Research

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  36. The formation of the molluscan shell is regulated to a large extent by a matrix of extracellular macromolecules that are secreted by the shell forming tissue, the mantle. This so called "calcifying matrix" is ...

    Authors: Benjamin Marie, Arul Marie, Daniel J Jackson, Lionel Dubost, Bernard M Degnan, Christian Milet and Frédéric Marin

    Citation: Proteome Science 2010 8:54

    Content type: Research

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  37. Prion diseases are fatal neurodegenerative disorders that accompany an accumulation of the disease-associated form(s) of prion protein (PrPSc) in the central nervous system. The neuropathological changes in the b...

    Authors: Fumiko Shinkai-Ouchi, Yoshio Yamakawa, Hideyuki Hara, Minoru Tobiume, Masahiro Nishijima, Kentaro Hanada and Ken'ichi Hagiwara

    Citation: Proteome Science 2010 8:53

    Content type: Research

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  38. The extracellular proteome or secretome of symbiotic bacteria like Rhizobium etli is presumed to be a key element of their infection strategy and survival. Rhizobia infect the roots of leguminous plants and estab...

    Authors: Niurka Meneses, Guillermo Mendoza-Hernández and Sergio Encarnación

    Citation: Proteome Science 2010 8:51

    Content type: Research

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  39. Currently, presence of Moraxella sp. in internal organs of fish is not considered detrimental for fish farming. However, bacterial colonization of internal organs can affect fish wellness and decrease growth rate...

    Authors: Maria Filippa Addis, Roberto Cappuccinelli, Vittorio Tedde, Daniela Pagnozzi, Iolanda Viale, Mauro Meloni, Fulvio Salati, Tonina Roggio and Sergio Uzzau

    Citation: Proteome Science 2010 8:50

    Content type: Research

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  40. The nematode Caenorhabditis elegans is both sensitive and tolerant to hypoxic stress, particularly when the evolutionarily conserved hypoxia response pathway HIF-1/EGL-9/VHL is involved. Hypoxia-induced changes i...

    Authors: Hualing Li, Changhong Ren, Jinping Shi, Xingyi Hang, Feilong Zhang, Yan Gao, Yonghong Wu, Langlai Xu, Changsheng Chen and Chenggang Zhang

    Citation: Proteome Science 2010 8:49

    Content type: Research

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  41. Enterococci have emerged as the third most common cause of nosocomial infections, requiring bactericidal antimicrobial therapy. Although vancomycin resistance is a major problem in clinics and has emerged in a...

    Authors: Hajer Radhouani, Patrícia Poeta, Luís Pinto, Júlio Miranda, Céline Coelho, Carlos Carvalho, Jorge Rodrigues, María López, Carmen Torres, Rui Vitorino, Pedro Domingues and Gilberto Igrejas

    Citation: Proteome Science 2010 8:48

    Content type: Research

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  42. Steroid-induced adipogenesis increases fat-cell volume and pressure in bone marrow. This may be a contributing factor in some forms of osteonecrosis. In this observational study, we aimed to determine the prot...

    Authors: Sing Chung Li, Ching Yu Lin, Tzong Fu Kuo, Yun Ho Lin, Chia Chun Chen, Way Neng Lin and Wing P Chan

    Citation: Proteome Science 2010 8:47

    Content type: Research

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  43. The phytopathogenic fungus Diplodia seriata, whose genome remains unsequenced, produces severe infections in fruit trees (fruit blight) and grapevines. In this crop is recognized as one of the most prominent path...

    Authors: Rebeca Cobos, Carlos Barreiro, Rosa María Mateos and Juan-José R Coque

    Citation: Proteome Science 2010 8:46

    Content type: Research

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  44. The silkworm Bombyx mori is a lepidopteran insect with four developmental stages: egg, larva (caterpillar), pupa, and adult. The hemolymph of the silkworm is in an open system that circulates among all organs, an...

    Authors: Yong Hou, Yong Zou, Fei Wang, Jing Gong, Xiaowu Zhong, Qingyou Xia and Ping Zhao

    Citation: Proteome Science 2010 8:45

    Content type: Research

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