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  1. The immune system must detect a wide variety of microbial pathogens, such as viruses, bacteria, fungi and parasitic worms, to protect the host against disease. Antigenic peptides displayed by MHC II (class II ...

    Authors: Wen-Jun Shen, Shaohong Zhang and Hau-San Wong
    Citation: Proteome Science 2013 11(Suppl 1):S15
    Content type: Research Published on:

    This article is part of a Supplement: Volume 11 Supplement 1

  2. Aeromonas salmonicida subsp. salmonicida, the etiologic agent of furunculosis, is a major pathogen of fisheries worldwide. Despite the identification of several virulence factors the pathogenesis is still poorly...

    Authors: Philippe Vanden Bergh, Manfred Heller, Sophie Braga-Lagache and Joachim Frey
    Citation: Proteome Science 2013 11:44
    Content type: Research Published on:

  3. Osteoarthritis (OA) is a destructive joint disease and there are no known biomarkers available for an early diagnosis. To identify potential disease biomarkers and gain further insight into the disease mechani...

    Authors: Johan Stenberg, Ulla Rüetschi, Eva Skiöldebrand, Johan Kärrholm and Anders Lindahl
    Citation: Proteome Science 2013 11:43
    Content type: Research Published on:

  4. Aeromonas salmonicida subsp. salmonicida, the etiologic agent of furunculosis, is a major pathogen of fisheries worldwide. Several virulence factors have been described, but the type-three secretion system (T3SS...

    Authors: Philippe Vanden Bergh, Manfred Heller, Sophie Braga-Lagache and Joachim Frey
    Citation: Proteome Science 2013 11:42
    Content type: Research Published on:

  5. Fusarium wilt of banana is one of the most destructive diseases in the world. This disease has caused heavy losses in major banana production areas. Except for molecular breeding methods based on plant defense...

    Authors: Xingshen Li, Tingting Bai, Yunfeng Li, Xiaolei Ruan and Huaping Li
    Citation: Proteome Science 2013 11:41
    Content type: Research Published on:

  7. Post treatment minimal residual disease (MRD) determination contributes to impending relapse prediction, chemotherapy response and clinical outcomes assessment, guiding clinicians to develop reasonable and eff...

    Authors: Ju Bai, Aili He, Wanggang Zhang, Chen Huang, Juan Yang, Yun Yang, Jianli Wang and Yang Zhang
    Citation: Proteome Science 2013 11:39
    Content type: Research Published on:

  8. Cell surface glycoprotein sialylation is one of the most ubiquitous glycan modifications found on higher eukaryotes. The surface sialylation pattern of cells is influenced by the cellular environment but also ...

    Authors: Ville I Parviainen, Sakari Joenväärä, Niina Tohmola and Risto Renkonen
    Citation: Proteome Science 2013 11:38
    Content type: Research Published on:

  9. Liver perfusates exhibit theoretical advantages regarding the discovery of disease biomarkers because they contain proteins that readily enter the blood-stream, and perfusion preserves the disease state in its...

    Authors: Yang Zhang, Menglin Li, Lilong Wei, Lisi Zhu, Siqi Hu, Shuzhen Wu, Sucan Ma and Youhe Gao
    Citation: Proteome Science 2013 11:37
    Content type: Research Published on:

  10. Two-dimensional gel electrophoresis (2DE) is one of the most popular methods in proteomics. Currently, most 2DE experiments are performed using immobilized pH gradient (IPG) in the first dimension; however, so...

    Authors: Rimantas Slibinskas, Raimundas Ražanskas, Rūta Zinkevičiūtė and Evaldas Čiplys
    Citation: Proteome Science 2013 11:36
    Content type: Research Published on:

  12. Aims of the research were to devise a proteome map of the chicken Pectoralis superficialis muscle, as resolved by two-dimensional gel electrophoresis, and to characterize protein expression changes in the soluble...

    Authors: Enrico Zanetti, Antonio Masi, Micaela Pivato, Serena Tolin, Anna Rita Trentin, Cem Guler, Servet Yalçin and Martino Cassandro
    Citation: Proteome Science 2013 11:34
    Content type: Research Published on:

  13. We report here a new type of protein chip to detect antibodies in sera. This chip method was used to a prototype created to detect hepatocellular carcinoma (HCC) -related autoantibodies in the sera of hepatiti...

    Authors: Junko Akada, Shuichi Kamei, Akane Ito, Moe Ito, Takao Kitagawa, Hiroko Furumoto, Yukari Kato, Michiko Tamesa, Motonari Takashima, Mutsunori Shirai, Hirofumi Yamano, Masaaki Oka, Yasuhiro Kuramitsu and Kazuyuki Nakamura
    Citation: Proteome Science 2013 11:33
    Content type: Methodology Published on:

  14. (−)-Epigallocatechin-3-gallate (EGCG), the most abundant catechin found in green tea, effectively reduces body weight and tissue and blood lipid accumulation. To explore the mechanism by which EGCG inhibits ce...

    Authors: Zhonghua Liu, Qin Li, Jianan Huang, Qionglin Liang, Yujun Yan, Haiyan Lin, Wenjun Xiao, Yong Lin, Sheng Zhang, Bin Tan and Guoan Luo
    Citation: Proteome Science 2013 11:32
    Content type: Research Published on:

  15. Transmissible gastroenteritis coronavirus (TGEV) is an enteropathogenic coronavirus that causes diarrhea in pigs, which is correlated with high morbidity and mortality in suckling piglets. Information remains ...

    Authors: Xin Zhang, Hong-Yan Shi, Jian-Fei Chen, Da Shi, Hong-Wu Lang, Zhong-Tian Wang and Li Feng
    Citation: Proteome Science 2013 11:31
    Content type: Research Published on:

  16. Hepatic fibrosis is an inevitable process in the progression of chronic HBV infection to hepatic cirrhosis, but its detailed mechanism is still unknown. Clinic serum biomarkers of HBV hepatic cirrhosis were sc...

    Authors: Bin Zhang, Zi Wang, Bin Deng, Xiaoqiong Wu, Jing Liu and Xueping Feng
    Citation: Proteome Science 2013 11:30
    Content type: Research Published on:

  17. A.BY/SnJ mice are used to study pathological alterations in the heart due to enteroviral infections. Since age is a well-known factor influencing the susceptibility of mice to infection, response to stress and...

    Authors: Krishnatej Nishtala, Truong Quoc Phong, Leif Steil, Martina Sauter, Manuela Gesell Salazar, Reinhard Kandolf, Stephan B Felix, Uwe Völker, Karin Klingel and Elke Hammer
    Citation: Proteome Science 2013 11:29
    Content type: Research Published on:

  18. The spore-bearing alkaliphilic Bacillus species constitute a large, heterogeneous group of microorganisms, important for their ability to produce enzymes, antibodies and metabolites of potential medical use. Some...

    Authors: Rosa Lippolis, Rosa Anna Siciliano, Maria Fiorella Mazzeo, Anna Abbrescia, Antonio Gnoni, Anna Maria Sardanelli and Sergio Papa
    Citation: Proteome Science 2013 11:28
    Content type: Research Published on:

  19. Aortic aneurysm is an increasingly common vascular disorder with fatal implication. However, there is no established diagnosis other than that based on aneurysmal size. For this purpose, serum protein biomarke...

    Authors: Kazumi Satoh, Tomoko Maniwa, Teiji Oda and Ken-ichi Matsumoto
    Citation: Proteome Science 2013 11:27
    Content type: Research Published on:

  20. Plant cells are routinely exposed to various pathogens and environmental stresses that cause cell wall perturbations. Little is known of the mechanisms that plant cells use to sense these disturbances and tran...

    Authors: Hana Mujahid, Feng Tan, Jian Zhang, Babi Ramesh Reddy Nallamilli, Ken Pendarvis and Zhaohua Peng
    Citation: Proteome Science 2013 11:26
    Content type: Research Published on:

  21. Salvia splendens Ker-Gawl, most commonly used in China to add a splash of brilliant color to the surroundings during the warm season, is subject to heat stress, which can greatly affect its growth and yield.

    Authors: Hui Liu, Guozheng Shen, Xianping Fang, Qiaojuan Fu, Kangkang Huang, Yi Chen, Hong Yu, Yun Zhao, Le Zhang, Liang Jin and Songlin Ruan
    Citation: Proteome Science 2013 11:25
    Content type: Research Published on:

    The Erratum to this article has been published in Proteome Science 2013 11:35

  23. There is great interest in the design of small molecules that selectively target minor grooves of duplex DNA for controlling specific gene expression implicated in a disease. The design of chiral small molecul...

    Authors: Ya-ting Yang, Chun-Yu Lin, Jingyueh Jeng and Chi-Wi Ong
    Citation: Proteome Science 2013 11:23
    Content type: Research Published on:

  24. Mapping of proteins involved in normal eye functions is a prerequisite to identify pathological changes during eye disease processes. We therefore analysed the proteome of human vitreous by applying in-depth p...

    Authors: Sebastian Aretz, Tim U Krohne, Kerstin Kammerer, Uwe Warnken, Agnes Hotz-Wagenblatt, Marion Bergmann, Boris V Stanzel, Tore Kempf, Frank G Holz, Martina Schnölzer and Jürgen Kopitz
    Citation: Proteome Science 2013 11:22
    Content type: Research Published on:

  25. Here we describe a novel approach used to identify the constituents of protein complexes with high fidelity, using the integrin-associated scaffolding protein PINCH as a test case. PINCH is comprised of five L...

    Authors: Masaaki Yoshigi, Stephen M Pronovost and Julie L Kadrmas
    Citation: Proteome Science 2013 11:21
    Content type: Methodology Published on:

  26. Bee venom has been used to relieve pain and to treat inflammatory diseases, including rheumatoid arthritis, in humans. To better understand the mechanisms of the anti-inflammatory and anti-atherosclerosis effe...

    Authors: Hyun-Ji Cho, Jeong-Han Kang, Kwan-Kyu Park, Jung-Yoon Choe, Yoon-Yub Park, Yong-Suk Moon, Il-Kyung Chung, Hyeun-Wook Chang, Cheorl-Ho Kim, Yung Hyun Choi, Wun-Jae Kim, Sung-Kwon Moon and Young-Chae Chang
    Citation: Proteome Science 2013 11:20
    Content type: Research Published on:

  27. Experimental autoimmune encephalomyelitis (EAE) is an autoimmune, inflammatory disease of the central nervous system that is widely used as a model of multiple sclerosis (MS). Mitochondrial dysfunction appears...

    Authors: Sausan Azzam, Laurie Broadwater, Shuo Li, Ernest J Freeman, Jennifer McDonough and Roger B Gregory
    Citation: Proteome Science 2013 11:19
    Content type: Research Published on:

  28. Neural Stem Cells (NSCs) are a distinct group of cells present in the embryonic and adult mammalian central nervous system (CNS) that are able to differentiate into neurons, astrocytes and oligodendrocytes. As...

    Authors: Ariel B Abraham, Robert Bronstein, Emily I Chen, Antonius Koller, Lorenza Ronfani, Mirjana Maletic-Savatic and Stella E Tsirka
    Citation: Proteome Science 2013 11:18
    Content type: Research Published on:

  29. SDS-PAGE followed by in-gel digestion (IGD) is a popular workflow in mass spectrometry-based proteomics. In GeLC-MS/MS, a protein lysate of a biological sample is separated by SDS-PAGE and each gel lane is sli...

    Authors: Sander R Piersma, Marc O Warmoes, Meike de Wit, Inge de Reus, Jaco C Knol and Connie R Jiménez
    Citation: Proteome Science 2013 11:17
    Content type: Methodology Published on:

  31. Vigna mungo, a tropical leguminous plant, highly susceptible to yellow mosaic disease caused by Mungbean Yellow Mosaic India Virus (MYMIV) resulting in high yield penalty. The molecular events occurring during c...

    Authors: Subrata Kundu, Dipjyoti Chakraborty, Anirban Kundu and Amita Pal
    Citation: Proteome Science 2013 11:15
    Content type: Research Published on:

  32. Refractory anemia and refractory anemia with ringed sideroblasts are two myelodysplastic syndrome (MDS) subgroups linked with anemia. MDS is a group of heterogeneous oncohematological bone marrow disorders cha...

    Authors: Pavel Májek, Zuzana Riedelová-Reicheltová, Jiří Suttnar, Klára Pečánková, Jaroslav Čermák and Jan E Dyr
    Citation: Proteome Science 2013 11:14
    Content type: Research Published on:

  33. The comprehensive analysis of human kidney glomerulus we previously performed using highly purified glomeruli, provided a dataset of 6,686 unique proteins representing 2,966 distinct genes. This dataset, howev...

    Authors: Zenyui Cui, Yutaka Yoshida, Bo Xu, Ying Zhang, Masaaki Nameta, Sameh Magdeldin, Tomoo Makiguchi, Toshikazu Ikoma, Hidehiko Fujinaka, Eishin Yaoita and Tadashi Yamamoto
    Citation: Proteome Science 2013 11:13
    Content type: Research Published on:

  34. Derived from Hobbit as the female parent and Zao5241 as the male parent, the elite soybean cultivar Jidou17 is significantly higher yielding and shows enhanced qualities and stronger resistance to non-biologic...

    Authors: Jun Qin, Feng Gu, Duan Liu, Changcheng Yin, Shuangjin Zhao, Hao Chen, Jianan Zhang, Chunyan Yang, Xu Zhan and Mengchen Zhang
    Citation: Proteome Science 2013 11:12
    Content type: Research Published on:

  35. Glycogen is a branched polysaccharide of glucose residues, consisting of α-1-4 glycosidic linkages with α-1-6 branches that together form multi-layered particles ranging in size from 30 nm to 300 nm. Glycogen ...

    Authors: David Stapleton, Chad Nelson, Krishna Parsawar, Marcelo Flores-Opazo, Donald McClain and Glendon Parker
    Citation: Proteome Science 2013 11:11
    Content type: Research Published on:

  36. This study examined the effect of storage temperature on the protein profile of human plasma. Plasma samples were stored for 13 days at -80°C, -20°C, +4°C and room temperature (20-25°C) prior to proteomic anal...

    Authors: Sara Pasella, Angela Baralla, Elisabetta Canu, Sara Pinna, James Vaupel, Marta Deiana, Claudio Franceschi, Giovannella Baggio, Angelo Zinellu, Salvatore Sotgia, Giuseppe Castaldo, Ciriaco Carru and Luca Deiana
    Citation: Proteome Science 2013 11:10
    Content type: Research Published on:

  37. Meat quality is a complex trait influenced by a range of factors with post mortem biochemical processes highly influential in defining ultimate quality. High resolution two-dimensional DIfference Gel Electrophore...

    Authors: Alessio Di Luca, Giuliano Elia, Anne Maria Mullen and Ruth M Hamill
    Citation: Proteome Science 2013 11:9
    Content type: Research Published on:

  38. Flour quality is largely determined by the gluten proteins, a complex mixture of proteins consisting of high molecular weight-glutenin subunits (HMW-GS), low molecular weight-glutenin subunits (LMW-GS), and α-...

    Authors: William J Hurkman, Charlene K Tanaka, William H Vensel, Roger Thilmony and Susan B Altenbach
    Citation: Proteome Science 2013 11:8
    Content type: Research Published on:

  39. A number of Tuber species are ecologically important. The fruiting bodies of some of these also have value as a cooking ingredient due to the fact that they possess exceptional flavor and aromatic properties. In ...

    Authors: Federico Vita, Valentina Lucarotti, Emanuele Alpi, Raffaella Balestrini, Antonietta Mello, Angela Bachi, Massimo Alessio and Amedeo Alpi
    Citation: Proteome Science 2013 11:7
    Content type: Research Published on:

  40. Arthrospira (Spirulina) platensis as a representative species of cyanobacteria has been recognized and used worldwide as a source of protein in the food, which possesses some unusual and valuable physiological c...

    Authors: Huili Wang, Yanmei Yang, Wei Chen, Li Ding, Peizhen Li, Xiaokai Zhao, Xuedong Wang, Aiying Li and Qiyu Bao
    Citation: Proteome Science 2013 11:6
    Content type: Research Published on:

  41. Mass spectrometry, an analytical technique that measures the mass-to-charge ratio of ionized atoms or molecules, dates back more than 100 years, and has both qualitative and quantitative uses for determining c...

    Authors: JA Koziol, NM Griffin, F Long, Y Li, M Latterich and JE Schnitzer
    Citation: Proteome Science 2013 11:5
    Content type: Methodology Published on:

  42. Cancer cell migration is fundamentally required for breast tumour invasion and metastasis. The insulin-like growth factor 1 tyrosine kinase receptor (IGF-1R) and the chemokine G-protein coupled receptor, CXCR4...

    Authors: Meizhi Niu, Manuela Klingler-Hoffmann, Julie A Brazzatti, Briony Forbes, Chareeporn Akekawatchai, Peter Hoffmann and Shaun R McColl
    Citation: Proteome Science 2013 11:4
    Content type: Research Published on:

  43. Deinococcus deserti VCD115 has been isolated from Sahara surface sand. This radiotolerant bacterium represents an experimental model of choice to understand adaptation to harsh conditions encountered in hot arid...

    Authors: Alain Dedieu, Elodie Sahinovic, Philippe Guérin, Laurence Blanchard, Sylvain Fochesato, Bruno Meunier, Arjan de Groot and Jean Armengaud
    Citation: Proteome Science 2013 11:3
    Content type: Research Published on:

  44. Beech bark disease is an insect-fungus complex that damages and often kills American beech trees and has major ecological and economic impacts on forests of the northeastern United States and southeastern Cana...

    Authors: Mary E Mason, Jennifer L Koch, Marek Krasowski and Judy Loo
    Citation: Proteome Science 2013 11:2
    Content type: Research Published on:

  46. Nitric oxide (NO) mediates its function through the direct modification of various cellular targets. S-nitrosylation is a post-translational modification of cysteine residues by NO that regulates protein funct...

    Authors: Akira T Komatsubara, Tomoya Asano, Hiroki Tsumoto, Kazuharu Shimizu, Takumi Nishiuchi, Masanori Yoshizumi and Kentaro Ozawa
    Citation: Proteome Science 2012 10:74
    Content type: Research Published on:

  47. Various factors shape the response of plants to herbivorous insects, including wounding patterns, specific chemical effectors and feeding habits of the attacking herbivore. Here we performed a comparative prot...

    Authors: Marc-Olivier Duceppe, Conrad Cloutier and Dominique Michaud
    Citation: Proteome Science 2012 10:73
    Content type: Research Published on:

  48. Perilla (Perilla frutescens) oil is very rich in α-linolenic acid, an omega-3 fatty acid. As it is widely reported that omega-3 fatty acid supplementation improves cognitive function in children and adults, feedi...

    Authors: Jinwoo Lee, Sunmin Park, Ju-Young Lee, Yeong Keun Yeo, Jong Sang Kim and Jinkyu Lim
    Citation: Proteome Science 2012 10:72
    Content type: Research Published on:

  49. Microarray technology may offer a new opportunity to gain insight into disease-specific global protein expression profiles. The present study was performed to apply a serum antibody microarray to screen for di...

    Authors: Philipp Mahlknecht, Sylvia Stemberger, Fabienne Sprenger, Johannes Rainer, Eva Hametner, Rudolf Kirchmair, Christoph Grabmer, Christoph Scherfler, Gregor K Wenning, Klaus Seppi, Werner Poewe and Markus Reindl
    Citation: Proteome Science 2012 10:71
    Content type: Research Published on:

  50. The urinary proteome has been widely used for biomarker discovery. A urinary proteome database from normal humans can provide a background for discovery proteomics and candidate proteins/peptides for targeted ...

    Authors: Xuejiao Liu, Chen Shao, Lilong Wei, Jindan Duan, Shuzhen Wu, Xuewang Li, Mingxi Li and Wei Sun
    Citation: Proteome Science 2012 10:70
    Content type: Research Published on:
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